The cortisol awakening response and the big five personality dimensions

The present study investigated the association between the big five personality dimensions and the cortisol awakening response (CAR), a physiological parameter reflective of HPA axis activity. One hundred and seven participants completed the big five inventory (BFI; John, Donahue, & Kentle, 1991) and collected salivary cortisol samples at 0, 30, and 60 min after awakening on a weekday morning. The cortisol awakening response under the curve (CARauc) and the cortisol awakening response with respect to increase (CARi) were used as outcome variables in the statistical analyses. Hierarchical linear regression analyses were conducted using the data of 92 participants. Gender and age were included as covariates in block one of the regressions, followed by the personality dimensions in block two. Extraversion emerged as a significant predictor of CARauc. No other personality dimensions were significantly predictive of CARauc or CARi. Interestingly, gender emerged as the strongest predictor in the CARauc, with females exhibiting greater cortisol release across the awakening period than males. Our results suggest that extraversion and gender may be particularly important variables to consider in the regulation of the HPA axis.     

On Chimeras

This essay is a critical response to Neville Cobbe's article “Cross‐Species Chimeras: Exploring a Possible Christian Perspective.” New technologies, particularly biotechnologies, raise major concerns in society. In the absence of good ethical thinking on these issues, bad ethical thinking becomes regnant. Two common types of bad ethical thinking are (1) confusing whatever disturbs people with genuine ethical issues and (2) confusing religious issues with ethical ones. Cobbe's article commits the former type of error with regard to the possibility of a mouse created with human brain neurons. I analyze and discuss that error and also raise questions about Cobbe's attempt to analyze the creation of chimeras from a Christian perspective.     

THE USE OF RESPONSE PREVENTION TO ELIMINATE NOCTURNAL THUMBSUCKING

The effects of a response prevention strategy consisting of the fading of restraint and the removal of reinforcers on nocturnal thumbsucking behavior was evaluated in four experiments. In the first experiment, nocturnal thumbsucking was restrained for approximately 1 week by having each of two boys wear a boxing glove to bed. Next they wore absorbent cotton over the thumb for 11 nights. During the last phase in this condition, they wore a fingertip bandage over the thumb for 10 to 11 nights. The response prevention package completely eliminated thumbsucking behavior in both boys. In the second experiment, the removal of reinforcers alone for nocturnal thumbsucking had little or no effect on the thumbsucking behavior of three girls whereas the later introduction of the entire package completely suppressed thumbsucking in all three girls. In the third experiment, the package was evaluated in the absence of the glove restraint condition. The results showed that the treatment package was effective in the absence of the glove restraint condition for all three children. The final experiment examined whether the package could be effective if the absorbent cotton condition was abruptly removed without using the fingertip bandage condition. The results showed the treatment to be effective with one of two boys, but not the other.     

腹部手术后舒芬太尼持续硬膜外镇痛与静脉镇痛的比较

采用双盲、前瞻性研究,在 60例年龄30岁～50岁,ASAⅠ-Ⅱ级,BMI（Body mass index体重指数）＜30kg/m^2,择期行下腹部手术患者中施行舒芬太尼术后镇痛。随机分为2组：硬膜外镇痛组（E组）和静脉镇痛组（Ⅰ组）,比较舒芬太尼术后持续静脉输注与静脉输注的半数有效浓度及副作用。结果显示E组舒芬太尼持续硬膜外输注的EC50（median effective concentration 半数有效浓度）为0.87μg/ml,95%的可信区间为0.79μg/ml～0.96 μg/ml ;Ⅰ组舒芬太尼持续静脉输注的EC50为0.63μg/ml,95%的可信区间为0.55μg/ml～0.70μg/ml ;恶心、呕吐、皮肤瘙痒发生率两组相似,Rammsay评分Ⅰ组＞E组。因此,舒芬太尼持续静脉输注的效价大于硬膜外输注,而硬膜外输注镇痛呼吸抑制副作用更少;并推测椎管内应用舒芬太尼主要作用部位仍在脊髓以上中枢。     

Unemployed people in search of a job: Reconsidering the role of search behavior

A three-wave longitudinal study of unemployed persons in Croatia was used to examine the antecedents of job-seeking behavior and reemployment. A series of demographic, motivational and job-constraint variables were posited to influence job-seeking behavior, which, in turn, was hypothesized to affect (re)employment. The participants were surveyed in 2003 (N = 1138), and their employment status was checked in 2004 (N = 601) and 2005 (N = 452). Regression analyzes supported only one slice of the model—the antecedent-job-search relations. All motivational variables, in particular employment commitment and perceived financial strain, proved to be relatively strong predictors of job-search intensity. However, they appeared to be only weakly related to the (re)employment outcome. Demographic variables—in particular education, age, and employment duration—appeared to be the main determinants of (re)employment, operating presumably through their influence on employers’ hiring decisions. It was suggested that existing theory and heuristic frameworks overstate the importance of job-seeking activity. Further research is suggested to examine why purposeful and proactive job searching does not pay more.     

Graded response model based on the logistic positive exponent family of models for dichotomous responses

Samejima (Psychometrika 65:319–335, 2000) proposed the logistic positive exponent family of models (LPEF) for dichotomous responses in the unidimensional latent space. The objective of the present paper is to propose and discuss a graded response model that is expanded from the LPEF, in the context of item response theory (IRT). This specific graded response model belongs to the general framework of graded response model (Samejima, Psychometrika Monograph, No. 17, 1969 and No. 18, 1972; Handbook of modern item response theory, Springer, New York, 1997; Encyclopedia of Social Measurement, Academic Press, San Diego, 2004), and, in particular to the heterogeneous case (Samejima, Psychometrika Monograph, No. 18, 1972). Thus, the model can deal with any number of ordered polytomous responses, such as letter grades (e.g., A, B, C, D, F), etc. For brevity, hereafter, the model will be called the LPEF graded response model, or LPEFG. This model reflects the opposing two principles contained in the LPEF for dichotomous responses, with the logistic model (Birnbaum, Statistical theories of mental test scores, Addison Wesley, Reading, 1968) as their transition, which provide a reasonable rationale for partial credits in LPEFG, among others.     

Reinforcer control by comparison-stimulus color and location in a delayed matching-to-sample task

Six pigeons were trained in a delayed matching-to-sample task involving bright- and dim-yellow samples on a central key, a five-peck response requirement to either sample, a constant 1.5-s delay, and the presentation of comparison stimuli composed of red on the left key and green on the right key or vice versa. Green-key responses were occasionally reinforced following the dimmer-yellow sample, and red-key responses were occasionally reinforced following the brighter-yellow sample. Reinforcer delivery was controlled such that the distribution of reinforcers across both comparison-stimulus color and comparison-stimulus location could be varied systematically and independently across conditions. Matching accuracy was high throughout. The ratio of left to right side-key responses increased as the ratio of left to right reinforcers increased, the ratio of red to green responses increased as the ratio of red to green reinforcers increased, and there was no interaction between these variables. However, side-key biases were more sensitive to the distribution of reinforcers across key location than were comparison-color biases to the distribution of reinforcers across key color. An extension of Davison and Tustin's (1978) model of DMTS performance fit the data well, but the results were also consistent with an alternative theory of conditional discrimination performance (Jones, 2003) that calls for a conceptually distinct quantitative model.     

Automatic imitation of intransitive actions

Previous research has indicated a potential discontinuity between monkey and human ventral premotor-parietal mirror systems, namely that monkey mirror systems process only transitive (object-directed) actions, whereas human mirror systems may also process intransitive (non-object-directed) actions. The present study investigated this discontinuity by seeking evidence of automatic imitation of intransitive actions--hand opening and closing--in humans using a simple reaction time (RT), stimulus-response compatibility paradigm. Left-right and up-down spatial compatibility were controlled by ensuring that stimuli were presented and responses executed in orthogonal planes, and automatic imitation was isolated from simple and complex orthogonal spatial compatibility by varying the anatomical identity of the stimulus hand and response hemispace, respectively. In all conditions, action compatible responding was faster than action incompatible responding, and no effects of spatial compatibility were observed. This experiment therefore provides evidence of automatic imitation of intransitive actions, and support for the hypothesis that human and monkey mirror systems differ with respect to the processing of intransitive actions.     

跨期选择的性质探索

跨期选择指人们对发生在不同时间点的价值做出的权衡与决策。大量研究证明, 跨期选择中人们存在普遍的时间折扣倾向, 即将未来的价值折扣后与当前价值进行权衡。跨期选择研究不仅与人类心智的起源与机制等基础科学问题密切相关, 也关系到国家公共政策的制定等现实问题。本项目拟采用实验室研究和大规模问卷调查结合的方法, 深入探索跨期选择的本质。一方面, 采用实验室研究法探讨影响跨期选择的重要因素, 以探索：(1) 跨期选择的效价及其与价值数量、延迟时间的交互作用及其心理机制; (2) 跨期选择中是否存在领域特异性及其心理机制; 另一方面, 通过全国范围的调查, 从而：(1) 建立中国城镇居民时间折扣率的常模; (2) 测量不同类型人群的时间折扣率, 以探讨跨期选择的性质与内涵。项目研究结果将有利于加深学界对跨期选择现象的理解。