The development of gyrification in childhood and adolescence

Gyrification is the process by which the brain undergoes changes in surface morphology to create sulcal and gyral regions. The period of greatest development of brain gyrification is during the third trimester of pregnancy, a period of time in which the brain undergoes considerable growth. Little is known about changes in gyrification during childhood and adolescence, although considering the changes in gray matter volume and thickness during this time period, it is conceivable that alterations in the brain surface morphology could also occur during this period of development. The formation of gyri and sulci in the brain allows for compact wiring that promotes and enhances efficient neural processing. If cerebral function and form are linked through the organization of neural connectivity, then alterations in neural connectivity, i.e., synaptic pruning, may also alter the gyral and sulcal patterns of the brain. This paper reviews developmental theories of gyrification, computational techniques for measuring gyrification, and the potential interaction between gyrification and neuronal connectivity. We also present recent findings involving alterations in gyrification during childhood and adolescence.     

儿童数概念发展的影响因素:表面相似性效应与标签效应

本研究主要考查表面相似性效应和标签效应对60名3～5岁儿童数概念发展的影响。实验通过等量匹配任务和数量比较任务测查儿童数概念的发展情况,其中等量匹配任务和数量比较任务都包括了一致和不一致两种条件以考查表面相似性效应对儿童数概念的影响,并通过给物取数任务、给数取物任务和等量匹配任务与数量比较任务的关系测查儿童使用数字标签的能力对儿童数概念形成与发展的影响。结果表明:(1)4岁和5岁组儿童完成等量匹配任务和数量比较任务的正确率显著高于3岁组儿童;(2)儿童在一致条件下完成等量匹配和数量比较任务的正确率显著高于不一致条件的正确率,表明物体的高表面相似性有利于儿童数概念的形成;(3)擅长使用数字标签的儿童完成等量匹配任务和数量比较任务的次数超过几率水平,使用数字标签有利于儿童数概念的发展。     

Facile route to synthesising mesoporous SBA-15 using phosphoric acid

A facile route has been developed to synthesise mesoporous SBA-15 using mild H₃PO₄ (replacing the most commonly used strong acid HC1) as the medium and the effects of H₃PO₄ concentration and synthesis temperature on the mesostructure and morphology of the resultant materials investigated. The results demonstrate that a more ordered structure can be obtained at low H₃PO₄ concentration (1–2?M), while a higher H₃PO₄ concentration (3–4?M) results in a less ordered structure. Furthermore, the morphology of SBA-15 particles transforms from rod-like to sphere-like with increasing H₃PO₄ concentration.     

语境和构词法线索对外国学生汉语词义猜测的作用

要求学习汉语的欧美和日本留学生对三种条件下(只有词没有语境、只有语境没有词、既有词也有语境)的语义半透明的双音复合词进行猜测, 考察语境和构词法线索在欧美和日本留学生汉语生词猜测中的作用。结果显示：在猜测词义中语境和构词法线索分别都能提供一定的信息, 但同时提供两种信息能得到更好的猜测; 语境和构词法线索在生词猜测过程中所起的作用不同, 语境能提供更多句法上的信息, 构词法能提供更多语义上的信息; 目标词的结构方式对生词猜测产生影响, 与动宾式生词相比, 偏正式生词的猜测较为容易且构词法线索在其中的作用较大; 母语文字背景可能影响词义猜测的效果, 日本留学生对于构词法、语境线索以及两者的整合都比欧美留学生好。     

白血病分型进展

白血病细胞因具有生物学的异质性、分化程度的差异性和细胞形态的多形性等特点,需要明确分型。而它的分型经历了FAB（法国、美国、英国协作组,French-American-British Co-operative group）分型、MIC（morphology,immunology and cytogenetic）分型,最后到MICM（morphology,immunology, cytogenetic and molecular）分型。     

Constrained canonical correlation

This paper explores some of the problems associated with traditional canonical correlation. A response surface methodology is developed to examine the stability of the derived linear functions, where one wishes to investigate how much the coefficients can change and still be in an -neighborhood of the globally optimum canonical correlation value. In addition, a discrete (or constrained) canonical correlation method is formulated where the derived coefficients of these linear functions are constrained to be in some small set, e.g., {1, 0, –1}, to aid in the interpretation of the results. An example concerning the psychographic responses of Wharton MBA students of the University of Pennsylvania regarding driving preferences and life-style considerations is provided.Wayne S. DeSarbo, Robert Jausman, Shen Lin, and Wesley Thompson are all Members of Technical Staff at Bell Laboratories. We wish to express our gratitude to the editor and reviewers of this paper for their insightful remarks.     

The relationship between phonological and morphological deficits in Broca's aphasia: further evidence from errors in verb inflection

A previous study of 10 patients with Broca's aphasia demonstrated that the advantage for producing the past tense of irregular over regular verbs exhibited by these patients was eliminated when the two sets of past-tense forms were matched for phonological complexity (Bird, Lambon Ralph, Seidenberg, McClelland, & Patterson, 2003). The interpretation given was that a generalised phonological impairment was central to the patients' language deficits, including their poor performance on regular past tense verbs. The current paper provides further evidence in favour of this hypothesis, on the basis of a detailed analysis of the errors produced by these same 10 patients in reading, repetition, and sentence completion for a large number of regular, irregular, and nonce verbs. The patients' predominant error types in all tasks and for all verb types were close and distant phonologically related responses. The balance between close and distant errors varied along three continua: the severity of the patient (more distant errors produced by the more severely impaired patients); the difficulty of the task (more distant errors in sentence completion>reading>repetition); the difficulty of the item (more distant errors for novel word forms than real verbs). A position analysis for these phonologically related errors revealed that vowels were most likely to be preserved and that consonant onsets and offsets were equally likely to be incorrect. Critically, the patients' errors exhibited a strong tendency to simplify the phonological form of the target. These results are consistent with the notion that the patients' relatively greater difficulty with regular past tenses reflects a phonological impairment that is sensitive to the complexity of spoken forms.     

Dissociations in performance on novel versus irregular items: single-route demonstrations with input gain in localist and distributed models

Four pairs of connectionist simulations are presented in which quasi-regular mappings are computed using localist and distributed representations. In each simulation, a control parameter termed input gain was modulated over the only level of representation that mapped inputs to outputs. Input gain caused both localist and distributed models to shift between regularity-based and item-based modes of processing. Performance on irregular items was selectively impaired in the regularity-based modes, whereas performance on novel items was selectively impaired in the item-based modes. Thus, the models exhibited double dissociations without separable processing components. These results are discussed in the context of analogous dissociations found in language domains such as word reading and inflectional morphology.     

子女越孝顺老年人越幸福吗?老年人孝道期待的作用

孝道是影响老年人幸福感的重要变量之一, 然而, 以往研究却得出相互矛盾的结论, 其中可能的重要原因之一是没有聚焦老年人孝道期待的实现程度。采用二次响应面回归分析探究老年人孝道期待和子女孝道支持行为之间的匹配度对老年人生活满意度和孤独感的影响。研究结果表明, 对于生活满意度而言, 和不匹配相比, 情感期待和情感支持以及联络期待和联络支持匹配时老年人生活满意度更高; 在期待和支持匹配的情况下, 生活满意度随信息期待和信息支持的增加而提高; 并且老年人的生活满意度仅随工具支持的增加而提高, 但与工具期待没有关系。对于孤独感而言, 在情感期待和情感支持二者不匹配时, 较于情感期待低于情感支持, 情感期待高于情感支持时老年人的孤独感更高; 孤独感仅随联络支持和信息支持的增加而降低, 与联络期待、信息期待、工具期待以及工具支持没有关系。该研究得出以下结论：老年人孝道期待的实现程度是提高其生活满意度的重要因素, 而情感期待高于情感支持是影响老年人孤独感的重要因素。     

Role of surface roughness in hysteresis during adhesive elastic contact

In experiments that involve contact with adhesion between two surfaces, as found in atomic force microscopy or nanoindentation, two distinct contact force (P) versus indentation-depth (h) curves are often measured depending on whether the indenter moves towards or away from the sample. The origin of this hysteresis is not well understood and is often attributed to moisture, plasticity or viscoelasticity. Here we report experiments which show that hysteresis can exist in the absence of these effects, and that its magnitude depends on surface roughness. We develop a theoretical model in which the hysteresis appears as the result of a series of surface instabilities, in which the contact area grows or recedes by a finite amount. The model can be used to estimate material properties from contact experiments even when the measured P–h curves are not unique.