Effects of setting and number of observations on generalizability of parent-child interactions in childhood obesity treatment

The generalizability of behaviors across observational conditions is a critical issue in behavioral assessment. Generalizability theory was used to examine two aspects of audio recorded parent-child interactions recorded over 6 days of home measurement and 1 day of laboratory measurement in a behavioral treatment program for childhood obesity. Families audiotaped parent-child home meetings during which they reviewed self-monitored diet and exercise records that were coded for the following types of interactions: praise statements, negative statements, prompts for new behaviors, and statements promoting problem solving. A similar meeting was audiotaped in our laboratory. The first question explored was the number of measurements needed to generalize to the universe of the six home measures. Results showed an increase in generalizability over measurements for each behavioral category. Using generalizability coefficients of .60 or more, praise, negative comments and prompts, respectively, could be reliably observed based on 1, 4, or 4 days of measurement. Second, the effects of setting (laboratory versus home) were assessed for 1 day of measurement in each environment. Again using generalizability coefficients of .60, generalizability analysis showed that the lab setting could not be generalized to the home setting based on 1 day of measurement, with generalizability coefficients ranging from .27 for negative comments to .57 for praise. Results suggest that 4 days of behavioral assessment in the home can be used to establish generalizable data for all the dependent measures studied. However, generalizability coefficients suggested that 1 day of laboratory measurement was not adequate to generalize to typical home behavior.This research was supported in part by Grant NIH HD 23713 awarded to the third author.     

Warmup in free-operant avoidance as a function of the response-shock = shock-shock interval

Warmup effects, the repeated within-session transitions from ineffective to effective avoidance, were examined with rats on free-operant shock-delay procedures. The shock-shock and response-shock intervals were kept equal as they were varied. As measured by both response rates and shock rates, the magnitude of within-session change in performance was inversely related to the size of the manipulated intervals. The duration of warmup tended to decrease as the intervals were increased. This finding, that increased shock frequencies do not shorten the warmup, appears to be inconsistent with all interpretations of the warmup that have been offered to date. Late-session performances replicated general features of prior experiments, but differed with respect to details of secondary conclusions in previous reports. These differences may stem from the selection of especially proficient avoiders for previous experiments.     

The concept of the death drive: A clinical perspective

This paper discusses Freud 's theory of the death drive in the light of clinical experience with severely self-destructive personality disorders, and contemporary object relations theory. Repetition compulsion, sadism and masochism, negative therapeutic reaction, suicide in depressed and in non-depressed patients, and destructive group processes are explored from this perspective. The paper concludes that the concept of the death drive is clinically relevant, but that this condition needs to be traced to the general dominance of aggressive affects as the primary etiological factor; only under severely pathological circumstances does this dominance lead to a focused drive to self-destruct.     

CREATING SINGLE‐SUBJECT DESIGN GRAPHS IN MICROSOFT EXCEL™ 2007

Over 10 years have passed since the publication of Carr and Burkholder's (1998) technical article on how to construct single‐subject graphs using Microsoft Excel. Over the course of the past decade, the Excel program has undergone a series of revisions that make the Carr and Burkholder paper somewhat difficult to follow with newer versions. The present article provides task analyses for constructing various types of commonly used single‐subject design graphs in Microsoft Excel 2007. The task analyses were evaluated using a between‐subjects design that compared the graphing skills of 22 behavior‐analytic graduate students using Excel 2007 and either the Carr and Burkholder or newly developed task analyses. Results indicate that the new task analyses yielded more accurate and faster graph construction than the Carr and Burkholder instructions.     

贫困问题:基于心理学的视角

贫困心理学,是在心理学视角下研究贫困问题的一种新研究取向,是心理学在贫困领域的最新运用。现阶段贫困心理学研究主要集中在主观幸福感、心理健康、行为决策等三个方面。贫困文化理论、稀缺理论、自我损耗论分别从贫困文化、稀缺心态以及意志力资源视角解释了贫困产生的心理机制。在摆脱贫困过程中需要打破贫困循环,未来贫困心理学研究需要进一步探讨贫困的产生机制、神经生理机制,贫困心理学的本土化研究以及心理学在扶贫工作中的应用等。     

From Assessment to Design: What Is Really Needed in Technology Accompaniment to Achieve Subject Constitution?

Based on the argument that technologies mediate human experience and praxis, the idea of technology accompaniment has been suggested as an approach to developing human-tech relations. In light of this idea, this paper argues, firstly, that when technologies inevitably have moral relevance in influencing human perceptions and actions, the constitution of a moral subject has much to do with shaping technological mediation deliberately and creatively. While there is not always a direct connection between what humans know and what humans do, technological mediation can help to strengthen people’s motivation to do the right thing. Subsequently, we examine two approaches that have often been suggested for realizing subject-constitution-with-technology: one is Technology Assessment, and the other is Mediation Design. Although the former can equip people with knowledge about technological mediation, it is relatively weak when it comes to directly producing moral behavior. In contrast, the latter not only exerts a more direct impact on user behavior but may also improve people’s moral knowledge. Nonetheless, both approaches face the general challenge of moral education. As moral knowledge does not guarantee moral behavior, knowing facts and theories about technological mediation may not lead to subject constitution as a result of the development of the human-tech relationship. To overcome this difficulty, an extension of the latter approach is proposed. The design of meta-mediation has great potential to shift users’ attention to the aforementioned mediating effect of technology-in-use and, thereby, users’ subject constitution can be enabled.     

论道德惩罚及其目的

道德惩罚作为一种非强制性的制裁手段对于规约和范导道德行为体的行为有着重要的作用。道德惩罚通过公共舆论、传统习俗、内心信念和道德良心等对违背道德法则的行为或坏的道德品质予以谴责,对社会道德风尚产生不良影响的行为体的道德权利予以限制和剥夺,从而促使该道德行为体实现由恶向善的转化,达到维护道德良知的、重申道德秩序的目的。     

Synchrnoic consciousness from a neurological point of view: the philosophical foundations for neuroethics

Daniel Kolak’s theory of synchronic consciousness according to which the entire range of dissociative phenomena, from pathologies such as MPD and schizophrenia to normal dream states, are best explained in terms of consciousness becoming simultaneously identified as many selves, has revolutionary therapeutic implications for neurology and psychiatry. All these selves, according to Kolak—even the purely imaginary ones that exist as such only in our dreams—are not just conscious but also self-conscious, with beliefs, intentions, living lives informed by memories (confabulatory, in the case of the fictional ones) and personal histories. Kolak’s derivation of psychiatrically relevant aspects of his theory—a neurological rendition of a Kantian transcendental argument—can be given a straightforward neurological, and therefore open to scientific scrutiny, interpretation that would then more easily lend itself to the clinical setting in which these perplexing phenomena, along with their purveyors, must live and cope. This will be the main focus of this paper.     

Review of Nie Minli’s Being and Substance: On Aristotle’s Metaphysics Z1–9

In his new book Being and Substance: A Study of Aristotle’s Metaphysics Z1–9, Nie Minli, taking a holistic perspective, argues that the primary substance—that is, the individual in Categories—is identical to form, which is the primary substance in Metaphysics Z, and that Z3 has finished arguing what the real candidate of substance is and the inserted Z7–9 texts are the “core and key” of the entire book. In spite of his excellent scholarship and masterful interpretation of Metaphysics Z4–6, Z7, Categories 1–5 and Physics Α, Nie offers insufficient textual support for his interpretation of the primary substance in Metaphysics Z and the content of Z3. Although substance is the subject (hypokeimenon) and a “this” (tode ti) in Categories, it is the ultimate subject (hypokeimenon eschaton) and a “this” (tode ti) and separable (choriston) in Metaphysics. As the ultimate subject, substance is form and matter but not the individual. As a “this” (tode ti) and separable (choriston), substance is form; moreover, the primary substance is form. In my view, that form is substance in Z3 serves more as a plan or outline needed to prove in the following than as a definite conclusion. This article also points out that tode ti in Z8, 1033b21 refers to the individual but not the form. Homōnuma in Z9 cannot be understood as “sharing the same name but with different meaning,” but, rather, simply as “having the same name.”     

幽门螺杆菌cagA基因多态性对临床结局的影响:东亚菌株和西方菌株

CagA蛋白是幽门螺杆菌最重要的毒力因子之一.目前已证实cagA基因存在东亚及西方两种亚型.幽门螺杆菌产生CagA蛋白,注入胃上皮细胞后在其羧基端EPIYA重复序列区进行酪氨酸磷酸化,进而与SHP-2酪氨酸磷酸化酶相互作用,参与上皮细胞的信号传导,导致细胞骨架结构的重排,引起细胞表面形状的改变和细胞动力的增强,造成细胞异常的增殖和运动,在胃癌的发生中起了主要作用.cagA基因的羧基端EPIYA重复序列被认为是区分东亚型和西方型菌株的分子标记,东亚型CagA与SHP-2亲和力大于西方型,最终影响着不同CagA+菌株感染的临床表现.