尿微量白蛋白与急性缺血性脑卒中的关系研究

探讨尿微量白蛋白（MA）与急性缺血性脑卒中（AIS）的关系。选取2012年1月1日～2014年3月31日于大连大学附属新华医院神经内科住院的缺血性脑卒中患者175例为研究对象。分为试验组：A1S患者103例;对照组：非AIS患者72例。比较两组的一般资料和MA阳性率情况。结果试验组的MA阳性率为41．75％,显著高于对照组MA的阳性率20．83％（P〈0．05）。MA与AIS可能有相关性,MA可能是AIS的危险因素。     

Categories in the pigeon brain: A reverse engineering approach

Pigeons are well known for their visual capabilities as well as their ability to categorize visual stimuli at both the basic and superordinate level. We adopt a reverse engineering approach to study categorization learning: Instead of training pigeons on predefined categories, we simply present stimuli and analyze neural output in search of categorical clustering on a solely neural level. We presented artificial stimuli, pictorial and grating stimuli, to pigeons without the need of any differential behavioral responding while recording from the nidopallium frontolaterale (NFL), a higher visual area in the avian brain. The pictorial stimuli differed in color and shape; the gratings differed in spatial frequency and amplitude. We computed representational dissimilarity matrices to reveal categorical clustering based on both neural data and pecking behavior. Based on neural output of the NFL, pictorial and grating stimuli were differentially represented in the brain. Pecking behavior showed a similar pattern, but to a lesser extent. A further subclustering within pictorial stimuli according to color and shape, and within gratings according to frequency and amplitude, was not present. Our study gives proof‐of‐concept that this reverse engineering approach—namely reading out categorical information from neural data—can be quite helpful in understanding the neural underpinnings of categorization learning.     

德州地区进展性缺血性脑卒中相关危险因素的研究

探讨进展性缺血性脑卒中（SIP）的相关危险因素。选择德州市人民医院1999年～2009年163例SIP患者,首先对18个变量行单因素分析,然后对阳性变量行多因素Logistic逐步回归分析,筛选SIP发生的相关危险因素。高血压史、感染、加拿大卒中量表（CNS）评分、高血糖、TG、纤维蛋白原、脑水肿、颈动脉粥样硬化性狭窄...     

ICU长期机械通气患者撤机困难的因素分析

为探讨ICU长期机械通气患者撤机困难的原因,回顾性分析大连医科大学附属第一医院重症医学科的62例长期机械通气患者的临床资料,回顾撤机过程,分析其撤机成功或失败的原因。结果显示,62例长期机械通气患者,34例成功撤机;10例死亡;18例因各种原因出现撤机困难,其中运动神经元病1例,脑外术后2例,间质性肺病4例,慢性阻塞性...     

Effect of tDCS on Fine Motor Control of Patients in Subacute and Chronic Post-Stroke Stages

Abstract

In this study we compared the effects of transcranial direct current stimulation (tDCS) in the subacute and chronic stages of post-stroke recovery. Anodal/sham tDCS was applied to the primary motor cortex of stroke patients in these stages of recovery in a cross-over design. The Jebsen–Taylor hand function test was employed. The repeated-measure ANOVA showed significant influence of the stimulation type and test performance time (during/after tDCS) with no overall influence of recovery stage. The interaction TYPE*TIME*STAGE was significant. The effect after anodal tDCS in the subacute stage was significantly higher compared to the effects in all relevant conditions including the chronic stage. Therefore, tDCS treatment in the subacute stage of recovery can be superior, at least for some patients, to treatment in the chronic stage.     

The effects of gender differences on the usability of automotive on-board navigation systems – A comparison of 2D and 3D display

This study integrated gender with the user interface of automotive on-board navigation systems to analyze whether gender differences or 2D (2 dimensional) vs. 3D (3 dimensional) display affect the interface usability of an on-board car navigation system (CNS). An experimental design was adopted for collecting data from three tasks – locating points, planning routes, and searching polygons – each emphasizing a different aspect of way-finding. The participants reported their subjective usability via the System Usability Scale after each trial. Study results show that gender, the CNS interface the subject used, and a combination of both predict the usability of an on-board CNS. This study’s results provide a clearer understanding of whether manufacturers should develop interfaces that fit a CNS 2D or 3D display based on gender.     

Multi‐Criteria Ratios: What is the Unit?

When Analytic Hierarchy Process ratios are normalized to sum to unity, the unit of measure becomes obscure. This paper investigates this obscurity and whether ratio measurement is possible when there is no prior knowledge of the measurement unit. Initially, we look at ratio scales of tangible attributes of objects with well‐known measures. Then, ratio scales of unknown intangible attributes of objects are analysed. We discover that natural zero and a specific unit of measure are not necessarily used explicitly in deriving ratio scale measures. Nevertheless, the derived scale does have a derived unit of measurement. We conclude that although composite multi‐criteria answers are possible in ratio form, it is important to know that a unit of measure exists if ambiguities are to be avoided. Copyright © 2011 John Wiley & Sons, Ltd.