How do we convert a number into a finger trajectory?

How do we understand two-digit numbers such as 42? Models of multi-digit number comprehension differ widely. Some postulate that the decades and units digits are processed separately and possibly serially. Others hypothesize a holistic process which maps the entire 2-digit string onto a magnitude, represented as a position on a number line. In educated adults, the number line is thought to be linear, but the “number sense” hypothesis proposes that a logarithmic scale underlies our intuitions of number size, and that this compressive representation may still be dormant in the adult brain. We investigated these issues by asking adults to point to the location of two-digit numbers on a number line while their finger location was continuously monitored. Finger trajectories revealed a linear scale, yet with a transient logarithmic effect suggesting the activation of a compressive and holistic quantity representation. Units and decades digits were processed in parallel, without any difference in left-to-right vs. right-to-left readers. The late part of the trajectory was influenced by spatial reference points placed at the left end, middle, and right end of the line. Altogether, finger trajectory analysis provides a precise cognitive decomposition of the sequence of stages used in converting a number to a quantity and then a position.     

Numerical approximation abilities correlate with and predict informal but not formal mathematics abilities

Previous research has found a relationship between individual differences in children’s precision when nonverbally approximating quantities and their school mathematics performance. School mathematics performance emerges from both informal (e.g., counting) and formal (e.g., knowledge of mathematics facts) abilities. It remains unknown whether approximation precision relates to both of these types of mathematics abilities. In the current study, we assessed the precision of numerical approximation in 85 3- to 7-year-old children four times over a span of 2 years. In addition, at the final time point, we tested children’s informal and formal mathematics abilities using the Test of Early Mathematics Ability (TEMA-3). We found that children’s numerical approximation precision correlated with and predicted their informal, but not formal, mathematics abilities when controlling for age and IQ. These results add to our growing understanding of the relationship between an unlearned nonsymbolic system of quantity representation and the system of mathematics reasoning that children come to master through instruction.     

Effect of Wii-Based Balance Training on Corticomotor Excitability Post Stroke

The objective was to examine the effectiveness of a 3-week balance training program using the Nintendo Wii Fit gaming system (Nintendo Wii Sports, Nintendo, Redmond, WA) on lower limb corticomotor excitability and other clinical measures in chronic stroke survivors. Ten individuals diagnosed with ischemic stroke with residual hemiparesis received balance training using the Wii Fit for 60 min/day, three times/week, for three weeks. At the end of training, an increase in interhemispheric symmetry of corticomotor excitability of the tibialis anterior muscle representations was noted (n = 9). Participants also showed improvements in reaction time, time to perform the Dual Timed-Up-and-Go test, and balance confidence. The training-induced balance in corticomotor excitability suggests that this Wii-based balance training paradigm has the potential to influence neural plasticity and thereby functional recovery.     

Neurodevelopmental Disorders Across the Lifespan: A Neuroconstructivist Approach.

Objectives. To investigate neuropsychological and neurobehavioral outcome in children with arterial ischemic stroke (AIS).

Background. Childhood stroke can have consequences on motor, cognitive, and behavioral development. We present a cross-sectional study of neuropsychological and neurobehavioral outcome at least one year poststroke in a uniquely homogeneous sample of children who had experienced AIS.

Method. Forty-nine children with AIS aged 6 to 18 years were recruited from a specialist clinic. Neuropsychological measures of intelligence, reading comprehension, attention, and executive function were administered. A triangulation of data collection included questionnaires completed by the children, their parents, and teachers, rating behavior, executive functions, and emotions.

Key Findings. Focal neuropsychological vulnerabilities in attention (response inhibition and dual attention) and executive function were found, beyond general intellectual functioning, irrespective of hemispheric side of stroke. Difficulties with emotional and behavioral regulation were also found. Consistent with an “early plasticity” hypothesis, earlier age of stroke was associated with better performance on measures of executive function.

Conclusions. A significant proportion of children poststroke are at long-term risk of difficulties with emotional regulation, executive function, and attention. Data also suggest that executive functions are represented in widespread networks in the developing brain and are vulnerable to unilateral injury.     

Cognitive Functioning,Behavior, and Quality of Life After Stroke in Childhood

Rationale: To provide a better understanding of cognitive functioning, motor outcome, behavior and quality of life after childhood stroke and to study the relationship between variables expected to influence rehabilitation and outcome (age at stroke, time elapsed since stroke, lateralization, location and size of lesion).

Methods: Children who suffered from stroke between birth and their eighteenth year of life underwent an assessment consisting of cognitive tests (WISC-III, WAIS-R, K-ABC, TAP, Rey-Figure, German Version of the CVLT) and questionnaires (Conner's Scales, KIDSCREEN).

Results: Twenty-one patients after stroke in childhood (15 males, mean 11;11 years, SD 4;3, range 6;10–21;2) participated in the study. Mean Intelligence Quotients (IQ) were situated within the normal range (mean Full Scale IQ 96.5, range IQ 79–129). However, significantly more patients showed deficits in various cognitive domains than expected from a healthy population (Performance IQ p?=?.000; Digit Span p?=?.000, Arithmetic's p?=?.007, Divided Attention p?=?.028, Alertness p?=?.002). Verbal IQ was significantly better than Performance IQ in 13 of 17 patients, independent of the hemispheric side of lesion. Symptoms of ADHD occurred more often in the patients' sample than in a healthy population (learning difficulties/inattention p?=?.000; impulsivity/hyperactivity p?=?.006; psychosomatics p?=?.006). Certain aspects of quality of life were reduced (autonomy p?=?.003; parents' relation p?=?.003; social acceptance p?=?.037). Three patients had a right-sided hemiparesis, mean values of motor functions of the other patients were slightly impaired (sequential finger movements p?=?.000, hand alternation p?=?.001, foot tapping p?=?.043). In patients without hemiparesis, there was no relation between the lateralization of lesion and motor outcome. Lesion that occurred in the midst of childhood (5–10 years) led to better cognitive outcome than lesion in the very early (0–5 years) or late childhood (10–18 years). Other variables such as presence of seizure, elapsed time since stroke and size of lesion had a small to no impact on prognosis.

Conclusion: Moderate cognitive and motor deficits, behavioral problems, and impairment in some aspects of quality of life frequently remain after stroke in childhood. Visuospatial functions are more often reduced than verbal functions, independent of the hemispheric side of lesion. This indicates a functional superiority of verbal skills compared to visuospatial skills in the process of recovery after brain injury. Compared to the cognitive outcome following stroke in adults, cognitive sequelae after childhood stroke do indicate neither the lateralization nor the location of the lesion focus. Age at stroke seems to be the only determining factor influencing cognitive outcome.     

Temperature-dependent crack surface tension

The fracture surface energy is calculated for a one-dimensional, exactly solvable model of a crack. The temperature dependence of the crack surface tension is determined on the basis of a self-consistent Einstein approach. It is found that lattice vibrations result in a strong reduction in the crack surface tension.     

Inhibitory stroke neighbour priming in character recognition and reading in Chinese

In alphabetic languages, prior exposure to a target word's orthographic neighbour influences word recognition in masked priming experiments and the process of word identification that occurs during normal reading. We investigated whether similar neighbour priming effects are observed in Chinese in 4 masked priming experiments (employing a forward mask and 33-ms, 50-ms, and 67-ms prime durations) and in an experiment that measured eye movements while reading. In these experiments, the stroke neighbour of a Chinese character was defined as any character that differed by the addition, deletion, or substitution of one or two strokes. Prime characters were either stroke neighbours or stroke non-neighbours of the target character, and each prime character had either a higher or a lower frequency of occurrence in the language than its corresponding target character. Frequency effects were observed in all experiments, demonstrating that the manipulation of character frequency was successful. In addition, a robust inhibitory priming effect was observed in response times for target characters in the masked priming experiments and in eye fixation durations for target characters in the reading experiment. This stroke neighbour priming was not modulated by the relative frequency of the prime and target characters. The present findings therefore provide a novel demonstration that inhibitory neighbour priming shown previously for alphabetic languages is also observed for nonalphabetic languages, and that neighbour priming (based on stroke overlap) occurs at the level of the character in Chinese.     

No strong evidence for lateralisation of word reading and face recognition deficits following posterior brain injury

Face recognition and word reading are thought to be mediated by relatively independent cognitive systems lateralised to the right and left hemispheres, respectively. In this case, we should expect a higher incidence of face recognition problems in patients with right hemisphere injury and a higher incidence of reading problems in patients with left hemisphere injury. We tested this hypothesis in a group of 31 patients with unilateral right or left hemisphere infarcts in the territory of the posterior cerebral arteries. In most domains tested (e.g., visual attention, object recognition, visuo-construction, motion perception), we found that both patient groups performed significantly worse than a matched control group. In particular, we found a significant number of face recognition deficits in patients with left hemisphere injury and a significant number of patients with word reading deficits following right hemisphere injury. This suggests that face recognition and word reading may be mediated by more bilaterally distributed neural systems than is commonly assumed.     

幼儿在集合比较中运用数数的实验研究

本研究中运用了两个实验探讨数数干预和测查条件对儿童在集合比较中运用数数的影响。干预对3岁儿童(M=3：9)没有影响。在平均年龄为4岁4个月时．干预组儿童比控制组儿童更倾向于用数数比较集合．自然组儿童也比传统组更倾向于用数数。许多4岁儿童在无干预时不用数数可能是因为,1)不知数数比视觉性比较更有效,或2)他们在集合比较中的数数极易受测查情景因素的影响。儿童在集合比较中的数数运用与他们的数数水平密切关联。