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排序方式: 共有622条查询结果,搜索用时 15 毫秒
111.
Jessica R. Donze Kenneth P. Tercyak 《Journal of clinical psychology in medical settings》2006,13(2):161-168
Few evidence-based health behavior interventions for adolescent survivors of childhood cancer currently exist. These interventions are necessary to address a range of lifestyle and behavioral factors (e.g., diet and physical activity, tobacco and alcohol use, excessive sun exposure) that may place survivors at increased risk for secondary cancers other chronic diseases. To address this need, the development and evaluation of a health promotion and disease prevention program for childhood cancer survivors is described, with an emphasis on the steps leading up to conducting a randomized controlled trial to test its efficacy. Data gathered from trial participants suggest the preliminary evaluation of the intervention is favorable. Trends and future directions in behavioral intervention research with childhood cancer survivors are discussed, along with the role of behavioral research in health promotion and disease prevention. 相似文献
112.
本文通过明晰的表格形式列出国际上不同国家历年麻醉药品的医疗消耗量,比较了发达国家与发展中国家的具体数据,并通过各国吗啡人均消耗量来揭示我国目前贯彻“癌症三阶梯止痛方案”与国际发达国家的差距。旨在强调对麻醉药品的管理,一方面要严格控制以免滥用造成危害,另一方面还要保证足够的医疗消耗。 相似文献
113.
子宫内膜癌是妇科常见的恶性肿瘤,发病机制不很清楚,早期诊断及治疗可改善预后,而目前的手术治疗方式损伤较大。Survivin是近年发现的新凋亡抑制基因,在多数恶性肿瘤组织中表达丰富,而在正常成人组织中不表达,这种表达特异性使其成为肿瘤诊断和基因治疗的新靶点。本文着重思考以Survivin为靶点的基因治疗方法在子宫内膜癌中的应用。 相似文献
114.
This study examined the impact of a genetics education module provided by Reach to Recovery peer volunteers. Participants
included 113 women with confirmed breast cancer diagnoses. Eighty-eight of these women (78%) completed a baseline survey,
participated in a peer-led intervention, and completed a follow-up survey. Approximately half of the women received an education
module that included a genetic component, while the other half did not. Results indicated that women who received the genetics
module had greater increases in genetics knowledge than the group that did not receive the module. However, follow-up interest
in genetic testing was not significantly different between the two groups. Results indicate that a peer-led genetics module
can increase knowledge about genetics. However, it does not appear to have a differential effect on genetic testing interest. 相似文献
115.
Palmero EI Ashton-Prolla P da Rocha JC Vargas FR Kalakun L Blom MB Azevedo SJ Caleffi M Giugliani R Schüler-Faccini L 《Journal of genetic counseling》2007,16(3):363-371
Hereditary breast cancer (HBC) accounts for 5–10% of breast cancer cases and it significantly increases the lifetime risk
of cancer. Our objective was to evaluate the sociodemographic variables, family history of cancer, breast cancer (BC) screening
practices and the risk profile of cancer affected or asymptomatic at-risk women that undergo genetic counseling for hereditary
breast cancer in public Brazilian cancer genetics services. Estimated lifetime risk of BC was calculated for asymptomatic
women using the Gail and Claus models. The majority of women showed a moderate lifetime risk of developing BC, with an average
risk of 19.7% and 19.9% by the Gail and Claus models, respectively. The average prior probability of carrying a BRCA1/2 gene mutation was 16.7% and overall only 32% fulfilled criteria for a hereditary breast cancer syndrome as assessed by family
history. We conclude that a significant number of individuals at high-risk for HBC syndromes may not have access to the benefits
of cancer genetic counseling in these centers. Contributing factors may include insufficient training of healthcare professionals,
disinformation of cancer patients; difficult access to genetic testing and/or resistance in seeking such services. The identification
and understanding of these barriers is essential to develop specific strategies to effectively achieve cancer risk reduction
in this and other countries were clinical cancer genetics is not yet fully established. 相似文献
116.
Utilization of cancer genetic risk assessment can be profoundly influenced by an individuals’ knowledge of risk assessment,
attitudes regarding illness and healthcare, and affective reactions derived from social norms. Race and ethnicity play a powerful
role in the development of an individual's attitudes and should be considered when attempting to understand a person's openness
to cancer genetic risk assessment (Lannin et al., 1998). Until recently, however, cancer screening and prevention programs have been primarily based on data from studies
conducted with the Caucasian population, yielding data that are not fully applicable to the African American community. In
the last several years, research findings regarding African American's knowledge, attitudes, and feelings about genetic counseling
and testing have grown (Matthews et al., 2000; Singer et al., 2004; Thompson et al., 2003). However, to the authors’ knowledge, these data have yet to be presented in a manner that both summarizes the barriers
that African Americans have reported regarding cancer genetic risk assessment, while at the same time suggesting methods individual
genetic counselors can utilize during community presentations to help address these barriers. This article will first summarize
previous empirical findings regarding African Americans’ knowledge, attitudes, and feelings about cancer genetic risk assessment.
The article will then apply adult learning theory to those findings to provide genetic counselors with practical, theory based
techniques to apply toward community based educational programs with African American groups. 相似文献
117.
Matthew J. Cordova Janine Giese-Davis Mitch Golant Carol Kronenwetter Chang Vickie David Spiegel 《Journal of clinical psychology in medical settings》2007,14(4):308-319
Diagnosis and treatment of cancer has been associated with both posttraumatic stress disorder (PTSD) symptoms and posttraumatic
growth (PTG). This cross-sectional study sought to assess the frequency, common predictors, and interrelationships of PTSD
symptoms and PTG in breast cancer survivors (n = 65). In this sample, symptoms of PTSD and reports of PTG were common and were not significantly related to one another.
Greater social constraints on talking about breast cancer and perception of cancer as a traumatic stressor were associated
with greater PTSD symptomatology. Younger age and perception of cancer as a traumatic stressor were associated with greater
PTG. Findings suggest the central role of subjective appraisal in adjustment to cancer. Psychosocial interventions should
be sensitive to the potential for PTG, both in treatment design and in assessment of outcomes. 相似文献
118.
Abraham P. Buunk Thecla M. Brakel Femke T.C. Bennenbroek Heidi E. Stiegelis Robbert Sanderman Alfons C. M. Van den Bergh Mariët Hagedoorn 《欧洲人格杂志》2009,23(6):475-487
The present study examined how the effects of three audiotapes containing different types of social comparison information on the mood of cancer patients depended on the level of neuroticism. On the procedural tape, a man and woman discussed the process of radiation therapy, on the emotion tape, they focussed on emotional reactions to their illness and treatment, while on the coping tape they focussed on the way they had been coping. A validation study among 115 students showed that the tapes were perceived as they were intended. The main study was conducted among 226 patients who were about to undergo radiation therapy. Compared to patients in the control group, as patients were higher in neuroticism, they reported less negative mood after listening to the procedural and the coping tape. Furthermore, as patients were higher in neuroticism, they reported less negative mood after listening to the coping tape than to the emotion tape. Copyright © 2009 John Wiley & Sons, Ltd. 相似文献
119.
癌痛治疗指南解析 总被引:4,自引:0,他引:4
对多国成人癌痛指南进行检索、回顾,发现近年癌痛治疗领域新进展和各国普遍遵循的共同原则,为临床医生改进癌痛治疗提供参考。采用现有的互联网临床实践指南检索平台,对成人癌痛指南进行检索,分析各国指南的异同之处,重点对疼痛评估、WHO三阶梯药物治疗及辅助治疗进行比较、归纳。全面的癌痛评估是指痛治疗的必要前提,也是众多癌痛指南强调的重点;按疼痛程度选择三阶梯镇痛药物仍是药物止痛的基本原则;口服途径是止痛治疗的首选给药途径;第一阶梯药物中阿司匹林的应用逐渐淡化,NSAIDs的毒性反应受到关注;第二阶梯药物的选择更灵活。应根据疼痛性质、患者的具体情况合理选择复合制荆。吗啡仍是强阿片类药物中的首选,可用于中、重度疼痛的治疗。因此,我国成人癌痛治疗需要改进,应重点推广全面的疼痛评估,提倡根据患者的具体情况合理、灵活的选择三阶梯药物,个体化治疗是止痛治疗的关键。 相似文献
120.
高危型别人乳头瘤病毒(HPV)感染在宫颈癌发生发展中具有重要作用。由于HPV L1蛋白结构特征及其精确的抗原特性,在粘附宿主细胞、识别病毒受体、协助病毒DNA的入胞转运中均发挥重要作用。检测患者宫颈损伤组织中L1蛋白的表达将有助于对患者是否具有传染性进行评估。本文将深刻思考HPV L1功能及其在感染机体并引发癌变的机制,以期更好的解读宫颈癌发病原理并最终应用于,强床治疗。 相似文献