The Effect of Differential Post-Weaning Environment on the Rigidity of an Animal's Behavior

Seventy-two first, second and third grade boys and girls were administered seriation problems involving different combinations of shape and color variation. Success rates and latency scores were influenced by shape variation, but not by color variation or grade level. The failure to obtain predicted interactions between the effects of grade level and stimulus variation was attributed to the clarity of the relevant stimulus dimension.     

The relationship between Big-5 personality traits and cognitive ability in older adults – a review

It is well established that fundamental aspects of cognition such as memory and speed of processing tend to decline with age; however, there is substantial between-individual variability in levels of cognitive performance in older adulthood and in rates of change in cognitive abilities over time. Recent years have seen an increasing number of studies concerned with examining personality characteristics as possible predictors of some of this variability in cognitive aging. The purpose of this article is to review the literature, and identify patterns of findings regarding the relationships between personality (focusing on the Big-5) and cognitive ability across nonclinical populations of older adults. Possible mechanisms underlying associations of personality characteristics with cognition are reviewed, and assessed in the context of the current literature. Some relatively consistent relationships are identified, including positive associations between openness and cognitive ability, and associations of conscientiousness with slower rates of cognitive decline. However, the relationships between several personality traits and cognitive abilities in older adults remain unclear. We suggest some approaches to research design and analysis that may help increase our understanding of how personality differences may contribute to cognitive aging.     

A meta‐analysis of serotonin metabolite 5‐HIAA and antisocial behavior

During the past 25 years, researchers have examined the relationship between neurochemical variables and antisocial behavior in human adults, but none has been studied more intensely than the serotonin metabolite 5‐hydroxyindoleacetic acid (5‐HIAA). The goal of the current study was to employ meta‐analytic procedures to quantitatively evaluate selected evidence on the relationship between 5‐HIAA and antisocial behavior. It was expected that antisocial groups would show reduced cerebrospinal fluid 5‐HIAA compared with non–antisocial groups. This study also aimed to assess moderators that could influence the relationship between 5‐HIAA and antisociality. An electronic search and strict inclusion criteria identified 20 reports used in this meta‐analysis. Results showed a significant overall mean effect size (ES = –.45, P < .05) in the direction of lowered 5‐HIAA in antisocial vs. non–antisocial groups. A significant moderating effect for age indicated that groups comprised of antisocial individuals younger than 30 years exhibited larger negative effect sizes (ES = –1.37, P < .05) than groups with older subjects (ES = –.31, P < .05). There were no moderating effects for gender, target of violence, history of suicide, and alcoholism. Age effects may help explain age‐related declines in crime. The fact that effects did not differ based on other moderating variables supports models of reduced serotonin in antisocial individuals, regardless of type of crime or psychiatric problems. Aggr. Behav. 28:299–316, 2002. © 2002 Wiley‐Liss, Inc.     

Clinical cut‐off point for the Distrust dimension of the Dimensional Clinical Personality Inventory 2 (IDCP‐2)

The Clinical Dimensional Personality Inventory 2 (IDCP ‐2) is a 206‐item self‐report tool developed for the assessment of 12 dimensions (divided into 47 factors) of personality pathology. One of the scales comprising the instrument, the Distrust scale, is intended to provide psychometric information on traits closely related to the Paranoid Personality Disorder (PPD ). In the present research, we used the Item Response Theory and the Receiver Operating Characteristic curve analysis to establish a clinical meaningful cutoff for the Distrust scale. Participants were 1,679 adults, among outpatients diagnosed with PPD , outpatients diagnosed with other PD s, and adults from the community. The Wright map revealed that outpatients were located at the very high levels on the latent continuum of the Distrust scale, with a very large effect size for the mean difference between patients and non‐patients. The ROC curve supported a cutoff at −1.00 score in theta standardization which yielded 0.87 of sensitivity and 0.54 of specificity. Findings from the present investigation suggest the IDCP ‐2 Distrust scale is useful as a screening tool of the core features of the PPD . We address potential clinical applications for the instrument and discuss limitations from the present study.     

Evidence for Free Radical-Mediated Reduction of Lymphocytic 5′-Ectonucleotidase During Stress

Previously we showed that stress and depression could result in a 50% lowering of lymphocytic 5-ectonucleotidase (NT) which could be resolved by a diet high in antioxidants. This study suggested that high levels of free radicals mediated by stress/depression may be involved in lowering NT activities. The aim of the present study was to assess whether oxygen radicals could directly affect NT and whether excess free radicals generated in stress/depression may affect tissue ascorbate stores. Exam-stressed students and depressed patients were compared respectively to these students at low stress and depressed patients on high antioxidant intakes. In this study, NT correlated positively with tissue ascorbate stores. A range of antioxidants were tested as possible inhibitors of oxy radical interaction with NT using nitroblue tetrazolium reduction to for-mazan with superoxide anion. At physiological plasma concentrations, ascorbate inhibited this reduction but dehydroascorbate, tocopherol, retinol, selenium, urate, and reduced glutathione were ineffective. Superoxide anion directly reduced lymphocytic NT activity and this effect was reversed by either 100 molar ascorbate in vitro or a high antioxidant intake in vivo. In conclusion, the low NT activities and ascorbate stores found in stressed/depressed people appear to be mediated by higher levels of free radicals reported in these subjects. These conclusions are consistent with published reports of (1) normal NT levels in melancholic patients on high antioxidant diets; (2) heightened inflammatory reponses during stress/depression; (3) low serum levels of zinc in depressed patients.     

A clinical trial of continuous, intermittent and overlearning ‘bell and pad’ treatments for nocturnal enuresis

Sixty-one enuretic children were allocated sequentially to ‘standard’, ‘intermittent’ or ‘overlearning’ bell and pad treatment. The results suggest that the ‘overlearning’ modification of standard treatment was successful in bringing about a reduction in the relapse rate. The present status and implications of research into nocturnal enuresis were discussed in the light of the results of the investigation.     

Women's reactions to discrimination from members of the same or opposite sex

The effects upon women's self-evaluations of experiencing varying severity of failure in interpersonal competition against male vs. female opponents were explored. The results supported the hypothesis that self-esteem in women is more vulnerable to interpersonal rejection from men as opposed to other women. Specifically, subjects reported lower self-esteem when severe failure was due to the actions of alleged, male opponents rather than female ones. Also, severe failure elicited less favorable self-evaluations than mild failure only when the female subjects confronted male opponents. Finally, contrary to a defensive self-presentation hypothesis, subjects did not respond to discrimination from men by presenting themselves as being discrepant from the stereotype of women. Instead, subjects who interpreted their failure as reflecting prejudice on the part of men evaluated themselves more favorably on positive traits underlying the female stereotype.