Relationships Between Cortisol,Optimism, and Perseverance Measured in Two Military Settings

Optimism and perseverance are 2 important assets for soldiers to be able to perform competently in high-risk environments and to complete complex and stressful tasks. Traditionally, optimism is measured using questionnaires and most frequently in a retrospective manner, for example, after a mission is completed. As such, ability to persevere in challenging environments is generally taken into account when it is too late, that is, when the soldier is showing severe signs of deficiency or failing to persevere. Therefore, there is a need for more objective measurements with which to predict perseverance. We conducted and present 2 studies in which the hormone cortisol seems to play a key role, relating with optimism, and possibly predicting perseverance. In the first study, we measured cortisol levels during a computer-simulated military training mission. A significant correlation between cortisol levels and optimism measured by the revised Life Orientation Test (LOT-R) Scale was found. In the second study, we followed 29 recruits through a demanding military training course required for joining the Dutch Air Mobile Brigade. The recruits who persevered and completed the course had a higher cortisol response to a stressful training event compared with those who leave the course. A regression model showed that a combination of the soldiers’ optimism and cortisol response best predicted perseverance. This study shows that a combination of attitudinal instruments and a biomarker has potential for predicting military training course attrition.     

Emotional distress and tobacco demand during the menstrual cycle in female smokers

Fluctuations in ovarian hormones over the menstrual cycle contribute to cigarette reward, however less is known about menstrual cycle influences on emotional distress in female smokers. We examined between-group differences in emotional distress (negative affectivity, emotion dysregulation, distress intolerance) and hypothetical cigarette purchasing (i.e. tobacco demand) among female smokers at three different menstrual stages. Women (n = 32) were non-treatment seeking daily smokers not on hormonal contraceptive, and were currently in their follicular (estradiol-dominant; n = 10), early-mid luteal (progesterone-dominant; n = 15), and late-luteal phase (decreasing progesterone/estradiol; n = 7). Effect sizes are reported given the small sample. Women in the late-luteal phase, relative to the follicular and early-mid luteal phases, reported higher levels of negative affectivity (d = 0.69), emotion dysregulation (d = 1.03), and distress intolerance (d = ?0.86). Compared to the early-mid luteal and late-luteal phases, women in the follicular phase reported the highest hypothetical cigarette consumption when cigarettes were free (d = 0.71) and made the largest maximum expenditures on cigarettes (d = 0.74). Findings offer preliminary evidence that the late-luteal phase is characterized by emotional distress, and the follicular phase is associated with elevated tobacco demand, which if replicated could implicate ovarian hormones in emotion-focused smoking.     

Differential diagnosis of steroid-dependent nephrotic syndrome with psychosis: Practical and ethical issues

The present case illustrates practical and ethical issues that can be encountered by clinical psychologists providing consultation services in medical settings. The neuropsychological consultation service was asked to evaluate a 22-year-old male with psychosis, steroid-dependent nephrotic syndrome, and a family history of schizophrenia. MRI revealedmarked cortical atrophy. Clinical findings were consistent with (1) steroid inducedapparent atrophy, which has been shown to be reversible with withdrawal of steroids; (2) uremia secondary to steroid withdrawal; (3) cortical atrophy, found in some schizophrenics; or (4) an atypical, diffuse degenerative disorder. Clinical interview and psychological testing revealed significant thought disorder, prominent delusions, somatic hallucinations, and mood disturbance. Deterioration in social and academic functioning was also present. Except for impaired attention and concentration, neuropsychological evaluation showed no clear evidence of brain-based dysfunction. Further, neuropsychological results effectively ruled out a degenerative process and were not consistent with a steroid effects profile. A conclusive differential diagnosis of steroid induced psychosis versus severe psychopathology would require withdrawal from steroids and antipsychotics. In addition to the practical and ethical issues of withholding antipsychotics, steroid withdrawal would require either dialysis or renal transplant surgery. Decision making regarding dialysis dependency and the possibility of postsurgical psychosis secondary to true psychopathology were salient issues to both the patient and the treatment team.     

Biological Bases of Maternal Attachment

In recent years, there has been growing interest in investigating the processes affecting caregiving behavior. Recent studies of human and nonhuman primates have suggested that hormones can account, at least in part, for changes in caregiving motivation during pregnancy and the postpartum period and for variability in caregiving motivation and behavior among individuals. Although hormones may not be the primary determinants of caregiving, future research cannot afford to overlook the contribution that biological processes can make to normative and pathological attachment and parenting.     

The Impact of Exercise on Hormones Is Related to Autonomic Reactivity to a Mental Task

This study examined the effects of an acute physical stressor on salivary testosterone (Tsal) and cortisol (Csal) and their relationship with the autonomic responsiveness to a mental task in fit young men (n = 30). Salivary testosterone (Tsal) and cortisol (Csal) levels were determined before and after a maximal bicycle exercise. Heart rate (HR) and skin conductance levels (SCL) were continuously recorded before, during, and after a Stroop task. Tsal and Csal levels diminished while HR and SCL increased in response to stressors in all the sample. When subjects were distributed in function of their endocrine response to the physical stressor, high Tsal responders showed higher HR reactivity than low responders, and high Csal responders showed higher SCL reactivity and lower reaction time in the Stroop task. These results show that the influence of an acute physical stressor on hormones is associated with the autonomic responses to a mental task.     

心律失常发生的别差异

临盘床中某些心律失常的发生具有性别差异。女性同男性相比,其平均静息心率快,QT间期长,QRS波群时间短,QRS电压低。女性有更高的病态窦房结综合征、不适当性窦性心动过速、房室结折返性心动过速、右室特发性室速和长QT间期综合征引起的心律失常事件的发生率。而男性房室传导阻滞、颈动脉窦综合征、房颤、旁路导致的室上性心动过速、预激综合征、室颤、猝死、Brugada综合征和触发型室速的发生率高。这些差异有的与心律失常伴发的器质性心脏病男女发生率不同有关,另外性激素对离子通道的功能、表达的影响以及自主神经张力的差异在这些差异的产生中也具有重要作用。了解这些差异对女性心律失常处理具有重要的指导作用。     

From steroids to nation states: An integrated evolutionary approach to violent crime

Most evolutionary psychologists emphasize the individual level of analysis concerning violent crime and other dependent variables. This paper outlines a strategy for evolutionary explanation of societal variation across time as well as space and applies it to crimes of violence. The central idea is that individual adaptations for reproductive competition play out differently depending both on developmental context and societal conditions, including the marriage market. Violent crimes (murders, rapes, and assaults) are substantially higher in countries with a relative scarcity of men according to research using INTERPOL and World Health Organization data [Barber, N. (2000a). The sex ratio as a predictor of cross-national variation in violent crime. Cross-Cultural Research, 34, 264–282, Barber, N. (2009). Countries with fewer males have more violent crime: Marriage markets and mating aggression. Aggressive Behavior, 35, 49–56]. This is an apparent contradiction given that males are more criminally violent and likely reflects increased direct mating competition that evokes increased testosterone production for humans as for other species. The empirical evidence is discussed in terms of direct reproductive competition and various alternative explanations, particularly the “culture of violence” and socialization experiences are considered.     

Relationships between testosterone metabolism in the brain,other endocrine variables and intermale aggression in mice

Relationships between some endocrine variables (plasma testosterone and estradiol; in vitro gonadal biosynthesis from pregnenolone precursor and adrenocortical biosynthesis from progesterone precursor; in vitro activity of 17β-hydroxysteroid de-hydrogenase (17β-HSDH) and of aromatizing enzymes in the subcellular fractions of the brain) and isolation-induced inter-male aggressiveness were studied. A significant positive correlation was found between fighting behavior, measured by the number of wins in a series of paired encounters, and the activity of brain 17β-HSDH. A significant inverse correlation was found between fighting behavior and the activity of aromatizing enzymes in the nuclear fraction of the brain. No significant correlations were found between fighting and the other endocrine variables investigated. These results may suggest that the conversions testosterone → androstenedione and testosterone → estradiol in the brain play a role in the control of inter-male fighting in the mouse. These results may also account for the effect of repeated wins and defeats on brain steroidogenesis.