条件位置范式在疼痛研究领域的应用

在疼痛领域,基础研究传统上主要关注疼痛的感觉维度和诱发痛的机制,对疼痛的情绪维度和临床上更常见的自发痛研究较少,这造成了基础研究和临床应用的脱节.条件位置范式的诞生在一定程度上解决了这一问题.条件位置范式是研究药物奖赏和成瘾的经典范式.近10年来,它开始被应用到疼痛研究领域.本文系统总结了目前条件位置范式在疼痛领域的研究进展,主要包括应用条件位置厌恶范式研究疼痛情绪、应用条件位置偏爱范式探索自发痛机制以及进行镇痛药物筛选.最后,结合已有的研究,提出了未来条件位置范式在疼痛领域的应用方向.     

Nicotine vs. ethanol discrimination: Extinction and spontaneous recovery of responding

Studies regarding extinction and spontaneous recovery of the discriminative stimulus effects of drugs are limited. Eight rats were initially trained to discriminate nicotine (0.4 mg/kg) vs. ethanol (800 mg/kg). For four rats, itraperitaneal (IP) administrations of nicotine fifteen minutes prior to fifteen-minute training sessions served as a discriminative stimulus (S^D) for predicting food-reinforced lever pressing (VI-1 min). On other sessions ethanol functioned in predicting nonreinforcement (S^Δ). The stimulus roles of the drugs were counterbalanced for the remaining four rats. S^Δ and S^D sessions alternated quasi-randomly with two daily sessions at 1000 and 1400 hours. Discriminative control was not disrupted following ten extinction sessions under a non-drug/saline condition, but was disrupted following extinction sessions under the original training drugs. Instances of spontaneous recovery (SR) occurred throughout extinction under the drug condtions. There was no evidence for SR two weeks following extinction, but partial recovery four weeks following the final extinction phase. Contextual status (context renewal) had neither a restorative or disruptive impact on extiguished or discriminated responding, respectively. Theser results support and extend the limited number of other studies by demonstrating extinction and spontaneous recovery of responding discriminated bytwo distinct drugs. Some theoretical interpretations regarding history effects and training in the context of drug discrimination are entertained.     

Neuropsychological aspects of facial asymmetry during emotional expression: A review of the normal adult literature

This review focuses on facial asymmetries during emotional expression. Facial asymmetry is defined as the expression intensity or muscular involvement on one side of the face (“hemiface”) relative to the other side and has been used as a behavioral index of hemispheric specialization for facial emotional expression. This paper presents a history of the neuropsychological study of facial asymmetry, originating with Darwin. Both quantitative and qualitative aspects of asymmetry are addressed. Next, neuroanatomical bases for facial expression are elucidated, separately for posed/voluntary and spontaneous/involuntary elicitation conditions. This is followed by a comprehensive review of 49 experiments of facial asymmetry in the adult literature, oriented around emotional valence (pleasantness/unpleasantness), elicitation condition, facial part, social display rules, and demographic factors. Results of this review indicate that the left hemiface is more involved than the right hemiface in the expression of facial emotion. From a neuropsychological perspective, these findings implicate the right cerebral hemisphere as dominant for the facial expression of emotion. In spite of the compelling evidence for right-hemispheric specialization, some data point to the possibility of differential hemispheric involvement as a function of emotional valence. An earlier version of this paper by the first author was presented at the XV Annual Symposium of the Society of Craniofacial Genetics, July 12, 1992, Stanford University, Palo Alto, CA.     

Incidental teaching of language in the preschool

"Incidental teaching" denotes a process whereby language skills of labelling and describing are learned in naturally occurring adult-child interactions. In the present study, 15-min daily samples of the spontaneous speech of 11 children were recorded during free play over eight months of preschool. After incidental teaching of compound sentences, increases in unprompted use of compound sentences were seen for all the children, first directed to teachers, and then to children, in accordance with who attended to the children's requests for play materials. The incidental teaching procedure also stimulated spontaneous variety in speech, and appears to have general applicability to child learning settings.     

社会层级的内隐刻板印象：权力与地位的不同作用

采用探测词再认范式,考察社会层级的内隐刻板印象。结果发现,在能力推理上,无论地位高低,个体对高权力推理为积极的反应时显著长于消极,对低权力推理为消极的反应时显著长于积极;在热情推理上,无论权力高低,个体对高地位推理为积极的反应时显著长于消极,对低地位推理为消极的反应时显著长于积极。这表明,权力和地位在热情和能力维度的刻板印象中起着不同的作用,其中权力正向预测能力,地位正向预测热情。     

自闭症幼儿自主性共同注意的实验研究

为探索和发现自闭症幼儿的自主性共同注意的特征,以6名自闭症幼儿,以及在心理年龄与之匹配的弱智和正常儿童各6名作为研究对象,以实验和准实验的方法,进行此研究。同时还以秒为单位对实验过程与结果进行编码分析。结果表明,自闭症幼儿的自主性视觉方向所及目标物多于人,而人的目标中叉更多地锁定同伴而非教师。自闭症幼儿在唤起他人共同注意时多以“拉”和“抱”来替代指点行为。自主性共同注意的发生率与情绪有密切关系。     

心理距离对自发特质推理的影响

采用错误再认范式,考察了心理距离是否影响个体对他人行为的自发特质推理。实验1采用2（配对类型：图片-可推测的特质词、图片-不可推测的特质词）× 2（空间距离：近、远）的混合设计,要求被试判断特质词是否在前面的行为句中出现过,以探讨自发特质推理形成情况。结果表明,与近空间距离相比,被试对远空间心理距离的行为主体产生了更多的自发特质推理。实验2采用2（配对类型：图片-可推测的特质词、图片-不可推测的特质词）× 2（时间距离：近、远）的混合设计,被试反应与实验1相同。结果发现,与近时间心理距离相比,被试对远时间心理距离的行为主体产生了更多的自发特质推理。实验结果提示远心理距离比近心理距离更利于自发特质推理,并在解释水平理论的框架内对结果进行了讨论。     

自发走神和有意走神及其与元认知的关系

走神包括有意走神和自发走神两种类型,元认知对二者的影响可能不同。研究使用两维度走神量表和元认知-30量表,对国内部分高校学生的走神和元认知(元认知信念、元认知加工和认知自信判断)进行调查,结果显示:(1)走神可以划分为有意走神和自发走神;(2)失控和危险感既能预测自发走神也能预测有意走神,但认知自信只能预测自发走神,认知的自我意识只能预测有意走神。说明元认知对自发走神和有意走神的影响存在差异。