Inter-hemispheric remapping between arm proprioception and vision of the hand is disrupted by single pulse TMS on the left parietal cortex

Parietal cortical areas are involved in sensori-motor transformations for their respective contralateral hemifield/body. When arms of the subjects are crossed while their gaze is fixed straight ahead, vision of the hand is processed by the hemisphere ipsilateral to the arm position and proprioception of the arm by the contralateral hemisphere. It induces interhemispheric transfer and remapping. Our objective was to investigate whether a single pulse TMS applied to the left parietal cortical area would disturb interhemispheric remapping in a similar case, and would increase a simple reaction time (RT) with respect to a control single pulse TMS applied to the frontal cortical area. Two LED were superimposed and located in front of the subjects on the saggital axis. Subjects were asked to carefully fixate on these LED during each trial. The lighting of the red LED was used as a warning signal. Following the green one was illuminated after a variable delay and served as a go-signal. The hand for the response was determined before the start of each trial. TMS was applied to the left parietal, the left frontal cortical areas, or not applied to the subject. Results revealed that: (1) Irrespective of its location, single pulse TMS induced a non-specific effect similar to a startle reflex and reduced RT substantially (15 ms on average) with respect to a control condition without TMS (mean value = 153 ms). (2) Irrespective of TMS, RT were shorter when the right or the left hand was positioned in the right visual hemi-field (i.e. normal and crossed positions respectively). (3) Finally, RT increased when single pulse TMS was applied to the left parietal area and when hands were crossed irrespective of which hand was used. We concluded that interhemispheric sensori-motor remapping was disrupted by a single pulse TMS that was applied to the left parietal cortex. This effect was also combined with some visual attention directed towards the hand located on the right visual hemi-field.     

Structure images of unaged martensite containing a high carbon content

Abstract

A highly tetragonal (large c/a ratio) martensite in a Fe-4 wt% Al-1·6 wt% Mn-2 wt% Calloy, which is not aged and considered to be as ‘fresh’ as possible, has been observed by high-resolution electron microscope. From the arrangement of atom rows in the [010] structure image and the corresponding electron diffraction pattern, it is concluded that carbon atoms are clustered on the (305) plane. The unit structure of these carbon-clustered regions is similar to that of the modulated structure observed in Fe-C alloys, although a periodic layer distribution of carbon atoms is not observed.     

心理行为干预对乳腺癌患者情绪反应及免疫功能的影响

按随机和匹配原则,将40名乳腺癌放疗患者分入干预组和对照组。对干预组患者进行为期4周的心理行为干预,对照组仅接受相应的医药治疗。以肿瘤病人情绪适应问卷(MAC)和免疫测试法研究患者干预前后的情绪反应和免疫功能,探讨心理行为干预对乳腺癌患者情绪反应和免疫功能的影响。结果发现,心理行为干预有利于提高患者NK细胞活性(NKCA);并有助于维持放疗期间患者的白细胞水平。     

数量化维度特征搜索的影响因素探索

有关数量化维度特征搜索的研究表明 ,目标搜索斜率 (反应时间对呈现项目数量函数的斜率 )是由目标与干扰子之间的差异决定的 ,然而以往研究中其差异的值取决于具体的实验条件。根据韦伯定律 ,笔者推测 ,目标搜索斜率应由目标与干扰子之间的相对差异 (C)决定 ,C为目标值 (T)与干扰子值 (D)的差值与该干扰子值的比值。当C值对应相等时 ,不同几何形状刺激的目标搜索斜率应无差异。为此笔者分别采用圆 (实验一 )和三角形 (实验二 )进行实验研究。实验结果支持了上述假设 ,并发现目标大于干扰子时的目标搜索斜率对C值的函数是单调递减函数     

父母对幼儿消极情绪的反应方式与幼儿情绪调节能力的关系

以西安市280名幼儿及其家长为被试,采用问卷法考察母亲、父亲对幼儿消极情绪的反应方式对幼儿情绪调节能力的单独效应和联合效应。结果发现：（1）母亲对幼儿消极情绪的支持反应正向预测幼儿的情绪调节能力,非支持反应负向预测幼儿的情绪调节能力;（2）父亲对幼儿消极情绪的支持反应和非支持反应显著预测女孩的情绪不稳;（3）在女孩的情绪调节能力上,母亲和父亲非支持反应的交互作用显著,部分支持了分歧模型。     

顿悟体验的特性、结构和功能基础

顿悟体验是伴随顿悟问题解决过程的心理和现象学体验,主要包含伴随题解闪现的啊哈体验和因思维定势自动激活而催生的僵局阶段体验。现有研究显示,顿悟体验可能是多类认知与情绪要素构成,兼具认知和情绪加工特性的多维复合体。加工流畅性可部分解释顿悟体验的产生机制,杏仁核、眶额区和脑岛等情绪和奖赏加工的脑区则可能是其脑功能基础。未来须用多元方法从新旧交替视角深化两阶段顿悟体验的研究。     

灾难给我们的心理留下了什么？ ——创伤心理的根源及创伤后应激反应的脑机制

创伤是指灾难性或创伤性事件给个体带来的伤害,不仅指身体受伤害,还包括心理伤害。创伤因素引发的强烈的情感反应和心理阴影会形成创伤心理,处理不当会进一步发展成创伤后应激障碍。本文主要从心理学的角度来探讨了创伤性事件引起的创伤心理及其形成的根源和创伤后应激反应的脑机制,最后根据心理学最新的相关研究结果提出干预建议,为有关部门的工作提供一定的参考     

A Two-Factor Model of Defensive Pessimism and Its Relations With Achievement Motives

The author first examined the underlying factor structure of the defensive pessimism construct and its relations with achievement motives. The author used a sample of 542 Singaporean undergraduate students and found that defensive pessimism is a 2-factor construct that comprises (a) negative expectation, in which individuals worry about possible pitfalls, and (b) reflectivity, in which individuals put forth efforts to prevent possible pitfalls. Then, the author used a sample of 160 Singaporean undergraduate students for Study 2, which supported the proposed model in which mastery predicted the reflectivity factor of defensive pessimism, competition predicted the negative-expectation factor of defensive pessimism indirectly through the mediation of fear of shame, and negative-expectation factor predicted the reflectivity factor of defensive pessimism because, for the defensive pessimists, the act of worrying helps them to respond to their anxiety by initiating the planning process to direct efforts to prevent potential disasters.     

Rank order in pairs of communally nursing female mice (Mus musculus domesticus) and Maternal Aggression Towards Conspecific Intruders of Differing Sex

This study examined social behavior between pairs of unfamiliar lactating females, with litters of the same age, at different periods after parturition (3, 7, and 17 days). Tests were generally followed by the formation of communal rearing nests, and subsequent maternal attack on intruders of differing sex was assessed. In all three intervals lactating females showed ritualized attack with formation of clear dominance-subordination relationships before combining litters into communal nests. The dominant females in 90% of cases started to retrieve alien pups into their nests. Agonistic behavior and communal nest formation were most rapid when pups were around 3 days old. Maternal attack on conspecific intruders was mainly displayed by the dominant lactating females. Male and female intruders were equally attacked (in terms of frequency and intensity of attack), but there was less such aggression when pups were around 17 days of age. Nevertheless the topography of biting attack employed against female and male conspecific intruders was different. Females were attacked using a strategy avoiding bites to the head and ventral surface (indicative of “offensive” behavior) whereas males were severely bitten on vulnerable body regions (indicative of “defensive” behavior).     

浅析当前临床科学决策的几个影响因素

随着循证医学在我国的发展和"医疗举证责任倒置"等相关法律的实施,我国临床医生在进行诊治决策时已逐步向临床科学决策迈进。而防御性医疗、不健全的医疗制度及相关法律等却严重影响着这一科学决策的转变过程。只有有效解决了导致干扰科学决策的各种社会影响因素,如扩大基本医疗保险的覆盖率,实施医疗风险保险制度,提高医务人员认知和职业素质,保障行医安全等,临床科学决策的真正落实就大有希望。