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81.
Frontostriatal networks play critical roles in grounding action semantics and syntactic skills. Indeed, their atrophy distinctively disrupts both domains, as observed in patients with Huntington's disease (HD) and Parkinson's disease, even during early disease stages. However, frontostriatal degeneration in these conditions may begin up to 15 years before the onset of clinical symptoms, opening avenues for pre‐clinical detection via sensitive tasks. Such a mission is particularly critical in HD, given that patients’ children have 50% chances of inheriting the disease. Against this background, we assessed whether deficits in the above‐mentioned domains emerge in subjects at risk to develop HD. We administered tasks tapping action semantics, object semantics, and two forms of syntactic processing to 18 patients with HD, 19 asymptomatic first‐degree relatives, and sociodemographically matched controls for each group. The patients evinced significant deficits in all tasks, but only those in the two target domains were independent of overall cognitive state. More crucially, relative to controls, the asymptomatic relatives were selectively impaired in action semantics and in the more complex syntactic task, with both patterns emerging irrespective of the subjects’ overall cognitive state. Our findings highlight the relevance of these dysfunctions as potential prodromal biomarkers of HD. Moreover, they offer theoretical insights into the differential contributions of frontostriatal hubs to both domains while paving the way for innovations in diagnostic procedures.  相似文献   
82.
Adam Pryor 《Dialog》2018,57(1):5-11
Despite the awe and wonder that discoveries related to astrobiology inspire, the sheer volume and diversity of new discoveries related to space science can become overwhelming without meaningful frames of reference by which to organize our understanding of these phenomena. I suggest that a critical feature of the future of “astrotheology” relates to how it serves as an organizing correlate to astrobiology and space research. Considering that the prefix astro‐ has an amplicative and abductive effect on the fields of study to which it is applied, I contend that astrotheology implies a creative and constructive shift in how we conceptualize meaningful human being for theology that parallels how astrobiology effects a creative and constructive shift in how we conceptualize living systems.  相似文献   
83.
I present a viable learning trajectory for prospective elementary teachers’ number sense development with a focus on whole-number place value, addition, and subtraction. I document a chronology of classroom mathematical practices in a Number and Operations course. The findings provide insights into prospective elementary teachers’ number sense development. These include the role of standard algorithms and their relationship to the evolution of classroom mathematical practices that involve reasoning flexibly about number composition, sums, and differences.  相似文献   
84.
This paper constructs a theory according to which an intention is not a mental state but an action at a certain developmental stage. I model intention on organic life, and thus intention stands to action as (e.g.) tadpole stands to frog. I then argue for this theory by showing how it overcomes three problems: intending while (1) merely preparing, (2) not taking any steps, and (3) the action is impossible. The problems vanish when we see that not all actions are mature. Just as some frogs (such as tadpoles) are immature frogs, some actions (such as intentions) are immature actions.  相似文献   
85.
In two studies we assessed the role of distinctiveness threat, group‐based emotions (angst, fear, and anger), and prejudice on people's willingness to engage in collective action against immigrant groups. In Study 1 (N = 222) White British participants were either informed that in the next 40 years the proportion of immigrants in the UK is unlikely to change (control condition) or that there will be more immigrants than White British people living in Britain (threat condition). We obtained support for a sequential multiple mediator model in which threat predicted British people's willingness to engage in collective action via the emotions first and then prejudice. This finding was replicated in Study 2 with an Italian sample (N = 283). These results enhance understanding of when and why advantaged groups undertake collective action against disadvantaged groups by demonstrating that distinctiveness threats and emotions promote such actions.  相似文献   
86.
Tool use is typically explored via actor-tool interactions. However, the target-object (that which is being acted on) may influence perceived action possibilities and thereby guide action. Three different tool-target-object pairings were tested (Experiment 1). The hammering action demonstrated the greatest sensitivity and therefore subsequently used to further investigate target-object pairings. The hammer was removed as an option and instructions were provided using pictorial (Experiment 2), written (Experiment 3), and both pictorial and written formats (Experiment 4). The designed tool is chosen when available (Experiment 1) and when removed as a choice (i.e., the hammer), participants perform the same action associated with the designed tool (i.e., hammering) regardless of instruction method (Experiments 2, 3, and 4).  相似文献   
87.
Terror management theory assumes that death arouses existential anxiety in humans which is suppressed in focal attention. Whereas most studies provide indirect evidence for negative affect under mortality salience by showing cultural worldview defenses and self‐esteem strivings, there is only little direct evidence for implicit negative affect under mortality salience. In the present study, we assume that this implicit affective reaction towards death depends on people's ability to self‐regulate negative affect as assessed by the personality dimension of action versus state orientation. Consistent with our expectations, action‐oriented participants judged artificial words to express less negative affect under mortality salience compared to control conditions whereas state‐oriented participants showed the reversed pattern.  相似文献   
88.
In this introduction to the special issue, we describe some of the rewards and challenges of community‐based arts initiatives for our discipline. We explore the inherent tensions between art and science that are reflected in community‐based arts activities. We pose larger questions about researching community‐based arts activities and defining the arts as a means of promoting social change. The diversity of populations, settings, and issues represented by the papers in the special issue are described and a common set of values, methods of inquiry and action are discussed.  相似文献   
89.
This study investigates the acquisition of integrated object manipulation and categorization abilities through a series of experiments in which human adults and artificial agents were asked to learn to manipulate two‐dimensional objects that varied in shape, color, weight, and color intensity. The analysis of the obtained results and the comparison of the behavior displayed by human and artificial agents allowed us to identify the key role played by features affecting the agent/environment interaction, the relation between category and action development, and the role of cognitive biases originating from previous knowledge.  相似文献   
90.
There is increased recognition of the importance of well-designed scholarship on how immigration status and policies impact migrants in the United States, including those who are unauthorized. Some researchers have looked to community-based and participatory methods to develop trust, place migrants’ voices at the forefront, and engage collaboratively in using research as a tool for social change. This article reviews three ethical ambiguities that emerged in the process of a series of participatory action research (PAR) projects with migrants in the United States, many of whom were unauthorized. Specifically, three themes are discussed: (a) the tension between the human desire to respond to injustices, and the challenges of doing so in ways that recognize one’s privilege and power as an outsider and supports the migrants’ agency and autonomy; (b) the complex definition, explanation, and dimensions of “risk”; and (c) the complexity of using a methodology (PAR) that prioritizes participants’ collective identity and community in the context of regulations that are designed primarily to protect individuals.  相似文献   
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