Mechanism of isoflavone aglycone's effect on cognitive performance of senescence-accelerated mice

This study investigated the effect of isoflavone aglycone (IA) on the learning and memory performance of senescence-accelerated mice, and explored its neural protective mechanism. Results showed that SAM-P/8 senescence-accelerated mice treated with IA performed significantly better in the Y-maze cognitive test than the no treatment control (P<0.05). The cortex AchE activity, serum SOD and GSH-Px activities were notably higher (P<0.05). MDA concentration and the β-secretase activity in the hippocampal tissue were both lower (P<0.05). Additionally, the number of hippocampal neurons was increased and cell morphology was significantly improved. Data suggested that IA could indirectly increase concentration of the cholinergic neural transmitter Ach through regulation of AchE, therefore improving the central cholinergic function and enhancing the learning and memory ability. By reducing the β-secretase activity, IA could decrease the formation and deposition of insoluble Adebris, relieve the resulted toxicity and damage to neurons, and thereby effectively protect the nervous system.     

Marcus Borg's Emerging Paradigm for Christianity: The Interplay of GLBT Readers,Religious Text,and Social Environment

This study considered how participants affiliated with a Christian church responded to and socially constructed information while reading and discussing Marcus Borg's book The Heart of Christianity: Rediscovering a Life of Faith. Borg argues that the traditional paradigm of American Christianity must be replayed with a more progressive Christianity. This church serves a largely (but not exclusively) gay, lesbian, bi-sexual, transgender congregation (GLBT). The entire reading church cohort consisted of twelve groups with 96 participants and an outside comparison group of six readers. Group 10 of the church groups was studied using a field-based, research-participant approach. Members of Reading Group 10 reacted positively to Borg and appeared to have personally accepted levels of social constructionism. Other reading groups reacted more negatively to Borg. Pastoral assessments of the effectiveness are also offered.     

The Role of Goal Orientations in Explaining Academic Cheating in Students With Learning Disabilities: An Application of the Cusp Catastrophe

The purpose of the present study was to predict and explain the academic cheating behaviors of elementary school students with learning disabilities (LD) by applying the cusp catastrophe model. Participants were 32 students with identified LD from state governmental agencies although all both them and the typical students participated in the experimental manipulation (N = 480). Academic cheating was assessed using an empirical paradigm where true achievement was subtracted from achievement in a test without proper invigilation. Data analysis supported the proposed cusp catastrophe models, where mastery-related motives acted as asymmetry and performance goals as bifurcation variables respectively. These findings were confirmed with application of the interactive goal hypothesis (Barron & Harackiewicz, 2001), where the interactive approach and avoidance performance goal term functioned as a splitting factor in the relationship between adaptive motivation and performance.     

Stigmatised Identity and Service Usage in Disadvantaged Communities: Residents', Community Workers' and Service Providers' Perspectives

The impact of community stigmatisation upon service usage has been largely overlooked from a social identity perspective. Specifically, the social identity‐mediated mechanisms by which stigmatisation hinders service use remain unspecified. The present study examines how service providers, community workers and residents recount their experience of the stigmatisation of local community identity and how this shapes residents' uptake of welfare, education and community support services. Twenty individual and group interviews with 10 residents, 16 community workers and six statutory service providers in economically disadvantaged communities in Limerick, Ireland, were thematically analysed. Analysis indicates that statutory service providers endorsed negative stereotypes of disadvantaged areas as separate and anti‐social. The awareness of this perceived division and the experience of ‘stigma consciousness’ was reported by residents and community workers to undermine trust, leading to under‐utilisation of community and government services. We argue that stigmatisation acts as a ‘social curse’ by undermining shared identity between service users and providers and so turning a potentially cooperative intragroup relationship into a fraught intergroup one. We suggest that tackling stigma in order to foster a sense of shared identity is important in creating positive and cooperative service interactions for both service users and providers. Copyright © 2014 John Wiley & Sons, Ltd.     

Fundamental Beliefs,Origin Explanations and Perceived Effectiveness of Protection Measures: Exploring Laypersons' Chains of Reasoning About Influenza

Laypersons' chains of reasoning in explaining recent influenza outbreaks are investigated. Drawing on social representations theory, fundamental worldviews, that is, the belief in a dangerous world (BDW), are postulated to anchor explanations of disease origins, which in turn affect perceived effectiveness of protection measures. Our study, based on a longitudinal survey among the general public in Switzerland, showed that the lower people's BDW scores, the more they appeal to natural origins to explain outbreaks and the more they perceive official protection measures as effective. The higher people's BDW scores, the more they explain outbreaks via hygienic origins, which are linked with out‐group discrimination measures, and conspiracy origins, which are linked with lower perceived effectiveness of aid intervention measures. Copyright © 2013 John Wiley & Sons, Ltd.     

Resisting and Conforming to the ‘Lesbian Look’: The Importance of Appearance Norms for Lesbian and Bisexual Women

Appearance is one way in which lesbian and bisexual identities and affiliation to lesbian, gay, bisexual (LGB) subculture can be demonstrated. ‘Butch’ and ‘androgynous’ styles have been used by lesbian women to communicate a non‐heterosexual identity. However, some LGB appearance researchers have argued that there has been a mainstreaming and diversification of lesbian style in the last couple of decades, which has resulted in less distinction between lesbian and straight looks. This research draws on the Social Identity approach to explore contemporary style in lesbian and bisexual communities. Fifteen lesbian and bisexual women took part in semi‐structured interviews which were analysed using thematic analysis. Although some participants reported a diversification of lesbian style, most used the term ‘butch’ to describe lesbian style, and a ‘boyish’ look was viewed as the most common contemporary lesbian style. By contrast, most participants could not identify distinct bisexual appearance norms. The data provide evidence of conflicting desires (and expectations) to visibly project social identity by conforming to specific lesbian styles, and to be an authentic, unique individual by resisting these subcultural styles. Copyright © 2013 John Wiley & Sons, Ltd.     

Can you tickle yourself if you swap bodies with someone else?

The effect of the body transfer illusion on the perceived strength of self- and externally-generated “tickle” sensations was investigated. As expected, externally generated movement produced significantly higher ratings of tickliness than those associated with self-generated movements. Surprisingly, the body transfer illusion had no influence on the ratings of tickliness, suggesting that highly surprising, and therefore hard to predict, experiences of body image and first-person perspective do not abolish the attenuation of tickle sensations. In addition, evidence was found that a version of the rubber hand illusion exists within the body transfer illusion. We situate our findings within the larger debate over sensory attenuation: (1) there is an attenuation of prediction errors that depends upon the context in which sensory input is predicted (i.e., efference copy), and (2) sensory attenuation is a necessary consequence of self-generated movement irrespective of context (i.e., active inference). The results support the notion of active inference.     

A model-based cluster analysis of social experiences in clinically anxious youth: links to emotional functioning

Social difficulties are commonly associated with anxiety disorders in youth, yet are not well specified in the literature. The aim of this study was to identify patterns of social experiences in clinically anxious children and examine the associations with indices of emotional functioning. A model-based cluster analysis was conducted on parent-, teacher-, and child-reports of social experiences with 64 children, ages 7–12 years (M = 8.86 years, SD = 1.59 years; 60.3% boys; 85.7% Caucasian) with a primary diagnosis of separation anxiety disorder, social phobia, and/or generalized anxiety disorder. Follow-up analyses examined cluster differences on indices of emotional functioning. Findings yielded three clusters of social experiences that were unrelated to diagnosis: (1) Unaware Children (elevated scores on parent- and teacher-reports of social difficulties but relatively low scores on child-reports, n = 12), (2) Average Functioning (relatively average scores across all informants, n = 44), and (3) Victimized and Lonely (elevated child-reports of overt and relational victimization and loneliness and relatively low scores on parent- and teacher-reports of social difficulties, n = 8). Youth in the Unaware Children cluster were rated as more emotionally dysregulated by teachers and had a greater number of diagnoses than youth in the Average Functioning group. In contrast, the Victimized and Lonely group self-reported greater frequency of negative affect and reluctance to share emotional experiences than the Average Functioning cluster. Overall, this study demonstrates that social maladjustment in clinically anxious children can manifest in a variety of ways and assessment should include multiple informants and methods.     

Évaluation de l’orthographe des élèves dysphasiques en situation de narration communicative : variations selon le type d’orthographe,lexicale versus morphologique

IntroductionThe overall goal of the study was to draw, in French language, a complete picture of spelling abilities in young students with SLI, enrolling in ordinary classes.ObjectiveThe main aim was to show how the developmental trajectories of lexical spelling and the morphological spelling are different when a large age span is observed (7 to 18 years old).MethodsThe spelling abilities were evaluated through a narrative communicative. Two groups of students with SLI (7–11 years and 12–18 years) were compared with two groups of typical students matched on chronological age.ResultsThe lexical spelling was acquired before the morphological spelling for SLI and typical participants. At 12–18 of age, the SLI participants did not produce more lexical errors than the typical group. For the lexical spelling, at 7–11 years, the SLI participants had a specific difficulty with the segmentation of the words: they produced words that do not exist in the language and which by definition have no morphological markers.ConclusionThe SLI participants need more time to learn than the typical participants. At 7–11 years, before learning of morphology, they must be able to control segmentation the segmentation of words. The low number of morphological errors in the school SLI group of 7–11 years is not necessarily a sign of difficulty. The increase in the number of errors at 12–18 years is the sign that this problem has been exceeded and that the learning of the written morphological markers can really begin.