发挥中药在肿瘤症状处理中的作用——兼谈结直肠癌的中医“病证结合辨治”

改善症状是中医治疗晚期恶性肿瘤的优势,但简单的对症治疗显然体现不了中医的特色;辨证论治虽然是中医治疗的核心,但在对癌病本质的把握上缺乏理论和实践的支撑;单一的辨病论治强调以毒攻毒,却不能改善症状及预后。本文作者以对结直肠癌的治疗为例,认为抓主症,将病证与辨治相结合,有望较好地解决“症”“证”“病”三者的关系,在改善症状...     

基于机体反馈调控保护扭转肿瘤治疗思路

肿瘤的临床治疗经过漫长积极探索研究,中西医疗效均未取得成就性突破,本文穿越时空隧道,基于人类亿万年适应环境生存生物进化历程形成的精细反馈调控保护视角,循证机体实施反馈调控保护顽强延续生命依据,结合肿瘤病理生理机制,剖析肿瘤形成原因,追溯肿瘤临床治疗误区,扭转肿瘤治疗思路,引领肿瘤治疗新路径。     

肿瘤临床治疗中应关注肝脏

抗肿瘤细胞毒性药物有不同程度毒副作用,有些严重毒副反应是限制药物剂量或使用的直接原因。肝脏是药物代谢的主要器官,也是药物损伤的主要靶器官。随着临床肿瘤治疗关注治疗带来的副作用与关注疗效同等重要的发展,本文对抗肿瘤细胞毒性药物与肝损伤、发生机制、诊断、分型和临床治疗进展进行了阐述。     

对肿瘤排斥性抗原肽研究的哲学思考

对肿瘤抗原的认识历细了多个阶段,最后终于确定了它们的存在并以肿瘤排斥性抗原肽为研究的主要方向。伴随着免疫学等学科的发展,研究了ＴＲＡＰ的方法也在不断进步。大量ＴＲＡＰ的发现和应用,不仅为肿瘤病因学研究提供了实验基础,也为肿瘤免疫治疗拓展了新的途径。对ＴＲＡＰ的研究给了我们许多有益的哲学启示。     

抗血管生成与肿瘤休眠疗法

回顾抗血管生成与肿瘤休眠疗法的进展,研究肿瘤未成熟血管与实体肿瘤的关系,探讨抗血管生成疗法在肿瘤生长和转移中的作用。肿瘤新生血管在肿瘤的生长和转移中均有重要意义。现已证实,肿瘤的生长和转移具有血管依赖性,实体肿瘤生长至一定体积需要通过新生成的血管灌注获得营养,而且新生的未成熟血管结构缺陷,通透性增加,使得肿瘤 容易穿透而发生血行转移。     

Education for the Heart and Mind: Feminist Pedagogy and the Religion and Science Curriculum

Feminist educators and theorists are stretching the boundaries of what it means to do religion and science. They are also expanding the theoretical and practical frameworks through which we might present curricula in thosefields. In this paper, I reflect on the implications of feminist pedagogies for the interdisciplinary field of religion and science. I begin with a brief discussion of feminist approaches to education and the nature of the feminist classroom as a setting for action. Next, I present some theoretical and practical issues to consider when developing a feminist praxis and an antisexist curriculum. This leads into a discussion of the role of language and critical reflection in the religion and science classroom, the risks associated with reflective discourse, and considerations in the use of 'feminist' teaching tools such as small group work, journals, and portfolio assessment. Iconclude with a reflection on how feminist pedagogy promotes an epistemology that speaks to the hearts and minds of participants in the dialogue of religion and science.     

In the beginning was the rhyme? A reflection on Hulme,Hatcher, Nation,Brown, Adams,and Stuart (2002)

Phonological sensitivity at different grain sizes is a good predictor of reading acquisition in all languages. However, prior to any explicit tuition in alphabetic knowledge, phonological sensitivity develops at the larger grain sizes-syllables, onsets, and rimes-in all languages so far studied. There are also developmental differences in the grain size of lexical representations and reading strategies across orthographies. Phoneme-level skills develop fastest in children acquiring orthographically consistent languages with a simple syllabic (CV) structure, such as Finnish and Italian. For English, however, both "large" and "small" units are important for the successful acquisition of literacy.     

Scharffs' Application of Hopper's Concept: “Incohesion: Aggregation/Massification”

We begin by stating our understanding of the concepts presented in Hopper's paper, then comment on the clinical illustration, and conclude by describing two group situations in which we have applied the concepts we have taken from Hopper's paper. Hopper's fourth basic assumption applies to our work as individual psychoanalysts, family therapists, and group leaders because it integrates psychoanalytic and social understanding. We demonstrate how and why we find Hopper's idea to be a useful advance.     

肿瘤疫苗治疗肿瘤的前景

肿瘤疫苗的发展已经历了一个多世纪,20世纪50年代,人们开始了自体肿瘤疫苗的研究.使肿瘤疫苗(主动性免疫治疗)成为继手术、放疗、化疗之后的肿瘤治疗方法.肿瘤疫苗作为主动特异性免疫治疗,在临床中起到越来越重要的作用,人们开始尝试利用多种方法制备肿瘤疫苗并利用其促进机体免疫应答,从整体细胞,分子水平调控机体对肿瘤的免疫.目前肿瘤疫苗的研制已取得很大进展,给人类战胜肿瘤提供很大希望。     

外科手术在晚期乳腺癌中的作用与地位

首诊Ⅳ期乳腺癌的外科治疗是否获益,是当前热议的问题,目前争议很大。本文就外科手术在晚期乳腺癌中的作用与地位问题,进行了探讨,认为需要更多的实践才能得出结论;提出晚期乳腺癌外科手术治疗的辩证观点,即处理好局部与整体的关系,抓住主要矛盾,根据不同的分子分型进行个体化的治疗选择。