慢性应激对大鼠行为和免疫细胞热休克蛋白70表达的影响

目的：研究慢性不确定应激对大鼠急性整体热水浴后外周血和脾脏免疫细胞热休克蛋白70（Heat shock protein 70, HSP70）表达的影响。方法：随机将大鼠分成慢性应激组和控制组（每组14只）。通过4周的慢性不确定性应激诱发实验组大鼠明显的抑郁行为,此期间控制组大鼠正常饲养。随后给予大鼠42度整体热水浴刺激,维持直肠温度41度25min。热刺激后6h,采用流式细胞仪测定大鼠外周血和脾脏免疫细胞HSP70 水平。结果：与控制组大鼠相比,慢性应激大鼠在急性热刺激后HSP70合成明显减少。控制组大鼠的所有被检测的免疫细胞热应激后HSP70合成均明显增加。相反,慢性应激大鼠仅在外周血的单核细胞和粒细胞检测到HSP70合成增加,同时升高的水平明显低于控制组大鼠。结论：慢性应激降低大鼠免疫细胞HSP70的热诱导反应,提示HSP70保护性作用减弱可能参与了慢性应激损害免疫细胞功能的生物学过程     

Coping with anxiety and rebuilding identity: A psychosynthesis approach to culture shock

As the number of international students continues to increase worldwide, their experience of culture shock has been well-researched. Missing, however, from the culture shock literature is the perspective of psychosynthesis psychology and its methodology to deal with the affective, behavioral, and cognitive (ABC) aspects of shock and adaptation. This article illustrates two psychosynthesis techniques that student sojourners found helpful in their acculturation process. Firstly, the self-identification exercise eased anxiety, an affective aspect of culture shock. Secondly, the subpersonality model aided students in their ability to integrate a new social identity, the cornerstone of the cognitive aspect. With a new integrated identity, students changed their behavior (the second ABC component) and new creative energies were released. These qualitative findings are supported by the testimonies of nine international student sojourners in the Netherlands who received psychosynthesis counseling. In addition, a case study demonstrates subpersonality integration and its role in helping students to come into relationship with themselves as well as others. The self-identification exercise and subpersonality model are not only effective tools for aiding sojourners in their adaptation to a host country, but viable methodologies for anyone searching to synthesize a new personal and social identity.     

桡骨小头粉碎性骨折的两种治疗方法比较分析

分析比较切开复位内固定和人工桡骨小头置换方法治疗桡骨小头粉碎性骨折（MasonⅢ型）的临床疗效。回顾分析2012年10月～2014年3月收治的24例桡骨小头粉碎性骨折（MasonⅢ型）的临床资料,其中切开复位内固定治疗17例;桡骨小头置换7例,平均随访12个月（6个月～18个月）。根据Broberg Morrey评分系统以及术后影像进行评价比较,同时比较两组住院天数以及费用。结果评价比较显示两者疗效均佳,术后两者活动度和功能评分相近,两组住院天数相近,内固定组费用更低。桡骨小头粉碎性骨折须尽早进行解剖复住功能重建,切开复位内固定和桡骨小头置换疗效相当。     

Grain orientation effects on dynamic strength of FCC multicrystals at low shock pressures: a hydrodynamic instability study

Variability in local dynamic plasticity due to material anisotropy in polycrystalline metals is likely to be important on damage nucleation and growth at low pressures. Hydrodynamic instabilities could be used to study these plasticity effects by correlating measured changes in perturbation amplitudes at free surfaces to local plastic behaviour and grain orientation, but amplitude changes are typically too small to be measured reliably at low pressures using conventional diagnostics. Correlations between strength at low shock pressures and grain orientation were studied in copper (grain size?≈?800 μm) using the Richtmyer–Meshkov instability with a square-wave surface perturbation (wavelength = 150 μm, amplitude = 5 μm), shocked at 2.7 GPa using symmetric plate impacts. A Plexiglas window was pressed against the peaks of the perturbation, keeping valleys as free surfaces. This produced perturbation amplitude changes much larger than those predicted without the window. Amplitude reductions from 64 to 88% were measured in recovered samples and grains oriented close to 〈0 0 1〉 parallel to the shock had the largest final amplitude, whereas grains with shocks directions close to 〈1 0 1〉 had the lowest. Finite element simulations were performed with elastic-perfectly plastic models to estimate yield strengths leading lead to those final amplitudes. Anisotropic elasticity and these yield strengths were used to calculate the resolved shear stresses at yielding for the two orientations. Results are compared with reports on orientation dependence of dynamic yielding in Cu single crystals and the higher values obtained suggest that strength estimations via hydrodynamic instabilities are sensitive to strain hardening and strain rate effects.     

The effect of teachers’ emotional intensity and social support on burnout syndrome. A comparison between Italy and Switzerland

IntroductionSchool-related events require ability on the part of teachers to control their emotional intensity and maintain negative emotions at a low level without compromising their general well-being. Doudin and Curchod (2008) found that satisfaction with received support acted as a buffer against burnout.ObjectivesThe current research focused on risk and protective factors for burnout syndrome, while also taking into account the role of two different school systems. We hypothesized that emotional intensity and dissatisfaction with social support would affect teachers’ levels of burnout. On this basis, we investigated a range of predictive models for all measures of burnout in both Italian and Swiss teachers.MethodParticipants were 275 primary school teachers (Italian n = 140; Swiss n = 135). Teacher burnout, emotional intensity and dissatisfaction with support received were respectively assessed by means of: the Maslach Burnout Inventory (Maslach, Jackson, & Leiter, 1996), the Emotional Competence Questionnaire (Doudin & Curchod-Ruedi, 2010) and the Social Support Questionnaire (Doudin, Curchod-Ruedi, & Moreau, 2011).ResultsIn line with our hypotheses, in both Italian and Swiss samples, emotional intensity played a significant predictive role in relation to emotional exhaustion and personal accomplishment, whereas dissatisfaction with support received affected all measures of teacher burnout.ConclusionsOur results provide fresh evidence for the protective role of social support in a profession that is particularly at risk of burnout. More specifically, burnout was predicted by the same pattern of variables in Italian and Swiss teachers, with significant differences emerging between the two groups in relation to their satisfaction with support received.     

Prediction of true test scores from observed item scores and ancillary data

In many educational tests which involve constructed responses, a traditional test score is obtained by adding together item scores obtained through holistic scoring by trained human raters. For example, this practice was used until 2008 in the case of GRE^®General Analytical Writing and until 2009 in the case of TOEFL^® iBT Writing. With use of natural language processing, it is possible to obtain additional information concerning item responses from computer programs such as e‐rater^®. In addition, available information relevant to examinee performance may include scores on related tests. We suggest application of standard results from classical test theory to the available data to obtain best linear predictors of true traditional test scores. In performing such analysis, we require estimation of variances and covariances of measurement errors, a task which can be quite difficult in the case of tests with limited numbers of items and with multiple measurements per item. As a consequence, a new estimation method is suggested based on samples of examinees who have taken an assessment more than once. Such samples are typically not random samples of the general population of examinees, so that we apply statistical adjustment methods to obtain the needed estimated variances and covariances of measurement errors. To examine practical implications of the suggested methods of analysis, applications are made to GRE General Analytical Writing and TOEFL iBT Writing. Results obtained indicate that substantial improvements are possible both in terms of reliability of scoring and in terms of assessment reliability.     

Temperature dependence of the stacking fault energy of glide set-dissociated dislocations in Si

Recently, it was found that the dissociation distance of glide set dislocations introduced in Si just below the melting temperature by laser shock peening (LSP) is unusually wide (Iwata et al. J. Jpn Inst. Met. Materi.,79(2015),308–314). In order to distinguish whether or not this is to be attributed to uncorrelated motions of leading and trailing Shockley partials or the intrinsic temperature dependence of the stacking fault energy (SFE), dislocations introduced by LSP were annealed at 1350 °C, which should be high enough for the uncorrelated partials to assume the equilibrium correlated configuration. It was found that this unusual widening of a dissociated dislocation introduced by LSP is attributed to uncorrelated motions of Shockley partials. Following this conclusion, the temperature dependence of the intrinsic SFE of Si was determined on correlated dissociated dislocations up to near the melting temperature. The intrinsic SFE of Si shows only negligibly small temperature dependence from 400 °C up to near the melting temperature.     

The arms of the chimeras

This article seeks to compare the approach developed in 1974 by Michel de M'Uzan to the concept of the ‘chimera’ with Thomas Ogden's ( 1995 , 2005 ) reflections on ‘the analytic third’. This comparison shows that in spite of the different theoretical approaches, unconscious to unconscious communication – a subject of interest in contemporary psychoanalytic research – makes it possible to grasp the intersubjective data deployed in the field of the session. After reviewing M. de M'Uzan's conception of the ‘chimera’ – a product of the unconsciouses of patient and analyst alike, and which emerges during a process of depersonalization in the analyst – the author proposes her hypothesis of the chimera as a particular intersubjective third whose creation, in a hallucinatory state, makes it possible to gain access to the bodily and emotional basis of the trauma. The author describes the chimera as a mental ‘squiggle’ between the two members of the pair which finds expression in different forms; further, she considers that the chimera that seizes the analyst is underpinned by the unconscious affinities of traumatic zones in both protagonists, which permit the grounding, configuration and sharing of the territories of suffering, as apprehended in this paper.     

Planning for driving retirement: The effect of driving perceptions,driving events,and assessment of driving alternatives

Most older adults will eventually stop driving, but few engage in planning for driving retirement. This study assessed whether driving stress, enjoyment, confidence, concerning driving events, and assessment of driving alternatives influence planning. Demographic factors were also included. Data were collected via a mailed transportation survey, with a final sample of 551 older adults who currently drive. Linear regression analyses revealed that more driving retirement planning was associated with greater driving stress, less driving confidence, and a more positive view of driving alternatives. Driving enjoyment and recent concerning driving events were not significantly related. Among the control variables, race and income were significantly related to planning, suggesting that lower income and identifying as Black race were associated with more planning. Gender only approached significance, suggesting that females may plan more than males. Overall, these findings suggest that more driving retirement planning is warranted. Some of the groups known to be at increased risk for driving reduction and cessation plan more for that eventuality than their counterparts. Implications of the study and suggestions for future research are discussed.