Sleep disruption explains age-related prospective memory deficits: implications for cognitive aging and intervention

The high prevalence of sleep disruption among older adults may have implications for cognitive aging, particularly for higher-order aspects of cognition. One domain where sleep disruption may contribute to age-related deficits is prospective memory—the ability to remember to perform deferred actions at the appropriate time in the future. Community-dwelling older adults (55–93 years, N = 133) undertook assessment of sleep using actigraphy and participated in a laboratory-based prospective memory task. After controlling for education, sleep disruption (longer awakenings) was associated with poorer prospective memory. Additionally, longer awakenings mediated the relationship between older age and poorer prospective memory. Other metrics of sleep disruption, including sleep efficiency and wake after sleep onset, were not related to prospective memory, suggesting that examining the features of individual wake episodes rather than total wake time may help clarify relationships between sleep and cognition. The mediating role of awakening length was partially a function of greater depression and poorer executive function (shifting) but not retrospective memory. This study is among the first to examine the association between objectively measured sleep and prospective memory in older adults. Furthermore, this study is novel in suggesting sleep disruption might contribute to age-related prospective memory deficits; perhaps, with implications for cognitive aging more broadly. Our results suggest that there may be opportunities to prevent prospective memory decline by treating sleep problems.     

Screening for cognitive impairment in an Australian aged care assessment team as part of comprehensive geriatric assessment

Accurate detection of mild cognitive impairment (MCI) is important to stratify and address risk. Yet, few short cognitive screening instruments are validated for this. . In Australia, all clients referred to an Aged Care Assessment Team (ACAT) receive comprehensive geriatric assessment (CGA) including the Standardized Mini-Mental State Examination (SMMSE). We compared the accuracy of the quick mild cognitive impairment (Qmci) screen to the SMMSE in 283 participants: 195 with dementia, 47 with MCI, and 41 with subjective cognitive decline (SCD) in an Australian community-based ACAT. Both had similar accuracy in identifying dementia, AUC of 0.86 for the Qmci versus 0.93 for the SMMSE (p = 0.10), but the Qmci was more accurate than the SMMSE in differentiating MCI from SCD, AUC of 0.84 versus 0.71, respectively, p = 0.046. These suggest that the new, short (3–5 min) Qmci screenis appropriate for use in an ACAT or other units conducting CGA.     

急性有氧运动对认知表现的影响

急性有氧运动是持续时间在10~60分钟的一次有氧运动。急性有氧运动可暂时性地改变感觉敏感度、记忆、执行功能等认知功能, 但其对不同认知功能的影响效果存在差异, 干预结果受到个体体适能水平、运动强度和运动类型等因素的调节。目前用于解释急性有氧运动影响认知表现的理论有唤醒理论、前额叶功能衰退理论、神经内分泌模型和神经营养因子假说。未来的研究应加强对急性运动发挥作用机制的探究, 更多关注身心运动、团体运动等不同运动形式的干预效果, 以期为长期“运动处方”的开具提供依据。     

Posttraumatic Stress Disorder and executive dysfunction among children and adolescents: A Latent Profile Analysis

Background/ObjectiveThe current study aimed to examine the relationship between Posttraumatic Stress Disorder (PTSD) symptoms and executive dysfunction in children and adolescents after psychological trauma.MethodParticipants were 13,438 of children and adolescents aged 6 to 18 years exposed to the 2008 Wenchuan earthquake. PTSD and dysexecutive symptoms were assessed using the UCLA PTSD Reaction Index for Children and the Self-Report Dysexecutive Questionnaire. Latent Profile Analysis (LPA) was conducted using Mplus version 7.4. Subgroup differences in trauma exposure and quality of life were calculated using ANCOVA.ResultsA 4-class parallel model was found to best describe latent PTSD symptom profiles and executive dysfunction. Individuals in higher symptom groups showed more trauma exposure and lower quality of life.ConclusionsThis LPA study shed light on the relationship between PTSD and executive dysfunction symptoms in children and adolescents. The correlation between PTSD and executive dysfunction was maintained after individual differences were taken into consideration. Our findings provide a new view on how PTSD relates to executive dysfunction and several suggestions for treating child and adolescent PTSD patients.     

Impact of a brief auditory attention training on a modified colour-word Stroop task in a high anxiety and worry sample

Poor attentional control leads to attentional biases that are implicated in psychological distress. Attention Training Technique (ATT) is an auditory intervention designed to strengthen attentional control. Research indicates that ATT alleviates anxiety and depressive symptoms. This study is a randomised control trial with repeated measures that tested if a lab-based, single-exposure of ATT strengthened attentional control. Forty-six nonclinical, high anxiety/worry participants received either ATT or a sham control intervention. Attentional control was assessed using the standard and a modified version of the colour-word Stroop task. The modified version incorporated tactile interference to increase perceptual load. A series of mixed effects models, simple contrasts, and z-tests were used to evaluate if cross-modal interference worsened, and whether ATT was beneficial to, attentional control. Tactile interference increased reaction times but, when Stroop interference was controlled for, this was only true on incongruent trials. The impact of ATT was greatest under high perceptual load.     

人类大脑结构和功能的性别差异：来自脑成像研究的证据

大脑的性别差异近年来受到了广泛关注。脑成像技术的出现为脑结构和脑功能性别差异的研究开辟了新的道路。借助结构磁共振成像和弥散张量成像等脑结构信息, 以及脑电图、正电子发射断层扫描技术和功能性磁共振成像等脑功能信息, 当前研究主要探讨了脑灰质、脑白质和大脑的基线活动在脑局部区域、脑子系统、全脑连接组三个层次上的性别差异及其在年龄上的发展变化。此外, 为了更好地理解脑性别差异, 当前文章还探讨了脑性别差异研究领域的一些认识误区。有关脑性别差异的研究虽然已经取得了丰富的成果, 但现有的研究结果存在很多分歧, 仍然有深入挖掘的空间。未来应该加强对具有性别特异性的心理疾病脑机制的研究, 关注基因和环境对脑性别差异的交互作用, 并利用脑功能活动动态变化的特性、以及结合多模态的脑成像技术进一步阐明脑性别差异。     

心理干预对轻中度脑瘫儿童综合功能和生活质量的影响*

采用对照组和干预组前测、后测设计,对80名脑瘫儿童的综合功能和生活质量进行了测量,分析了心理干预对脑瘫儿童康复疗效的影响。结果表明:(1)四组脑瘫儿童后测综合功能评定效果存在显著差异。(2)生活质量问卷中,在使用特殊器具感觉维度上,四个组别间的追踪水平逐级显著递增;在对疼痛和困扰感觉维度上,四个组别间的后测水平、追踪水平均逐级显著递减;在其它四个维度上,四个组别间的后测水平、追踪水平均逐级显著递增。(3)在使用特殊器具感觉维度上,三个干预组内的追踪水平显著高于前测和后测水平;在对疼痛和困扰感觉维度上,三个干预组内的前测、后测和追踪水平均呈逐级显著递减趋势;在其它四个维度上,三个干预组内的前测、后测和追踪水平均逐级显著递增。干预组比对照组能显著提升脑瘫患儿的综合功能和生活质量。     

社会交往对老年人认知功能的影响

社会交往是影响老年人认知功能的重要因素。社会交往主要包括社会网络, 社会支持和社会参与三方面。研究发现, 社会交往对老年人的认知功能具有积极的影响, 但是网络类型比网络规模更有利于揭示社会网络与认知功能的关系, 而且社会支持并非越多越好, 对于易感性人群而言, 适度的支持才能避免造成认知损伤。此外, 尽管社会参与能够对认知功能产生持续的保护作用, 但不同活动类型作用于不同的认知领域。未来研究应该继续深化社会网络类型的作用, 进一步考察社会支持与认知功能的中介和调节变量, 并同时关注社会活动对认知功能的干预研究。     

To infinity and beyond: Children generalize the successor function to all possible numbers years after learning to count

Recent accounts of number word learning posit that when children learn to accurately count sets (i.e., become “cardinal principle” or “CP” knowers), they have a conceptual insight about how the count list implements the successor function – i.e., that every natural number n has a successor defined as n + 1 (Carey, 2004, 2009; Sarnecka & Carey, 2008). However, recent studies suggest that knowledge of the successor function emerges sometime after children learn to accurately count, though it remains unknown when this occurs, and what causes this developmental transition. We tested knowledge of the successor function in 100 children aged 4 through 7 and asked how age and counting ability are related to: (1) children’s ability to infer the successors of all numbers in their count list and (2) knowledge that all numbers have a successor. We found that children do not acquire these two facets of the successor function until they are about 5½ or 6 years of age – roughly 2 years after they learn to accurately count sets and become CP-knowers. These findings show that acquisition of the successor function is highly protracted, providing the strongest evidence yet that it cannot drive the cardinal principle induction. We suggest that counting experience, as well as knowledge of recursive counting structures, may instead drive the learning of the successor function.     

THE MISSING FATHER FUNCTION IN PSYCHOANALYTIC THEORY AND TECHNIQUE: THE ANALYST'S INTERNAL COUPLE AND MATURING INTIMACY

This paper argues that recovering the “missing” paternal function in analytic space is essential for the patient's achievement of mature object relations. Emerging from the helpless infant's contact with primary caregivers, mature intimacy rests on establishing healthy triadic functioning based on an infant‐with‐mother‐and‐father. Despite a maternocentric bias in contemporary clinical theory, the emergence of triangularity and the inclusion of the paternal third as a separating element is vital in the analytic dyad. Effective technique requires the analyst's balanced interplay between the paternal, investigative and the maternal, maximally receptive modes of functioning—the good enough analytic couple within the analyst—to serve as the separating element that procreatively fertilizes the capacity for intimacy with a differentiated other. A clinical example illustrates how treatment is limited when the paternal function is minimized within more collusive, unconsciously symbiotic dyads.