Validity of the strategic management simulations to predict real-world productivity

The performance of individual businesses and the economy as a whole hinges on the productivity of human capital, yet measuring productivity at an individual level has proved difficult. The Strategic Management Simulation (SMS) methodology comprises several decision-making assessment tools that have been used for several decades to estimate real-world productivity. Performance on productivity measures using a shorter version of the SMS methodology was gathered from a sample of 111 knowledge workers from major corporations in the U.S. and compared with their income level. In linear models, every percentile increase in SMS performance was associated with a $791–$1,113 increase in income in each of the four domains of decision-making performance provided by the SMS tool. The models had R²’s ranging from 0.65 to 0.75, indicating high levels of correlation between SMS performance and income levels. This study is the first to show linear relationships between SMS performance and other indicators of productivity, indicating that the SMS is a valid predictor of productivity and that SMS scores can be used to predict job satisfaction and performance.     

Murray Sidman's contributions to clinical behavior analysis

Murray Sidman was not himself a clinician nor directly involved in clinical research. Nevertheless, his experimental and conceptual work, especially in the area of stimulus equivalence, profoundly influenced the development of clinical behavior analysis. Before his work on stimulus equivalence, clinicians with a behavior analytic world view working with verbally sophisticated humans, were making some progress in understanding clinical phenomena and in developing innovative therapies. However, given the obvious and predominant role of verbal processes in both the development and treatment of clinical problems, that progress was constrained by the existing behavior analytic account of verbal behavior. Most fundamentally, it was hard to understand how, in the apparent absence of direct training, verbal events, even novel verbal events, acquire the functions of the nonverbal events that they stand for or represent. Sidman's work on stimulus equivalence, especially the transfer (transformation) of functions, offered an answer and thereby provided a conceptual framework of symbolic behavior around which clinical behavior analysis could cohere and develop.     

Nonsimultaneous stimulus presentations and their role in listener naming

Previous studies on naming have presented the object and its name simultaneously during both training and testing, and thus the training component may establish a transformation of function directly between the object and the name. Successful tests for listener naming may thus not require the emergence of a novel (entailed) transformation of function. The current study aimed to control for this possibility by presenting the object and the name sequentially and nonsimultaneously. Eight typically developing toddlers participated in the current study. During name training, objects and names were presented nonsimultaneously, and all participants failed to emit listener-naming responses during the first test session. Subsequently, 4 participants received multiple exemplar training, which led to improvements in listener naming for all 4; and speaker naming for only 1 participant. As a control condition, the remaining 4 participants were tested repeatedly, without multiple exemplar training, and did not show any consistent improvements in their listener or speaker performances. Multiple exemplar training thus appeared to be effective in establishing generalized listener responses, which involved generating entailed transformation of functions. The strategy of using nonsimultaneous stimulus presentations could allow for greater precision in identifying the behavioral processes involved in listener-naming.     

Parent-report and performance-based measures of executive function assess different constructs

A total of 405 children of 5–18 years of age were administered performance-based and parent-report measures of executive function (EF), and measures of motor, attention, reading, and mathematics performance. Attention, reading, and mathematics abilities were associated with a parent-report measure of EF. Reading and mathematics abilities were also associated with performance-based measures of EF, including the Animal Sorting, Inhibition, and Response Set subtests of the Developmental NEuroPSYchological Assessment-II. In contrast, motor functioning was only associated with performance-based measures of EF. Findings suggest that different constructs of EF are measured by parent-report versus performance-based measures, and that these different constructs of EF are associated with different neurodevelopmental processes.     

What Confucius practiced is good for your mind: Examining the effect of a contemplative practice in Confucian tradition on executive functions

The short-term training effects on various executive functions (EFs) by a movement-based contemplative practice (MBCP) are examined. Three aspects of EFs (working memory capacity, inhibition, switching) are assessed before and after a month-long 12-h training period using Body-Mind Axial Awareness (BMAA) principles that Confucius followers have practiced for more than 2000 years. A mindfulness-based practice (Chan-meditation) and a waiting-list control group served as contrast groups. Our results showed that the BMAA group performed better on the task that measured working memory capacity than did the Chan-meditation and the waiting-list groups after training. In addition, the Chan-meditation groups outperformed the control group on attentional switching, a novel finding for this kind of practice. Our findings not only show a new effect of short-term MBCPs on EFs, but also indicate movement-based and mindfulness-based contemplative practices might benefit development of various aspects of EFs in different ways.     

The interactive effects of age,education, and BMI on cognitive functioning

We examined the moderating effects of age and cognitive reserve on the relationship between body mass index (BMI) and processing speed, executive function, and working memory based on the literature suggesting that obese individuals perform more poorly on measures of these abilities. Fifty-six healthy, dementia-free community-dwelling older (mean age 65.72 ± 7.40) and younger (mean age 21.10 ± 2.33) adults completed a neuropsychological battery and reported height and weight. Mixed effects models were used to evaluate the interactive effects of age, education (a proxy for cognitive reserve), and BMI on cognitive scores. Higher education was protective for executive deficits in younger, but not older adults. Age differences in executive functions were reduced at higher education levels but increased in individuals with higher BMI. Results suggest the inter-relationships between cognitive reserve – as measured by education – and BMI differ across age, and that obesity may accelerate the cognitive aging process.     

抑郁症的脑结构与功能异常:来自静息态下多模态脑影像的研究证据

传统单一模态、单一分析方法在揭示抑郁症脑机制上存在较多局限;而新近多种模态、多种分析方法的结合可在一定程度上较好地促进对抑郁症脑功能和结构的全面探索、挖掘,可以更加有效地运用和实施于早期辅助诊断、干预治疗当中。因此,本文首先简要介绍了多种模态下的脑影像指标及其分析技术,而后分别从结构及功能神经影像数据融合等方面,概述了抑郁症脑结构和功能的研究现状,发现抑郁症患者存在诸多脑区及相关环路结构及功能的异常。同时,通过对抑郁症多模态研究现状的梳理和总结,结合我们已有的相关前期研究工作,对未来抑郁症等情感障碍的进一步研究工作提出了一些思考和展望。     

Premonitory urges are associated with decreased grey matter thickness within the insula and sensorimotor cortex in young people with Tourette syndrome

Tourette syndrome (TS) is a neurological disorder characterized by vocal and motor tics and is associated with cortical–striatal–thalamic–cortical circuit (CSTC) dysfunction and hyperexcitability of cortical limbic and motor regions, which are thought to lead to the occurrence of tics. Importantly, individuals with TS often report that their tics are preceded by ‘premonitory sensory phenomena’ (PSP) that are described as uncomfortable cognitive or bodily sensations that precede the execution of a tic, and are experienced as a strong urge for motor discharge. While the precise role played by PSP in the occurrence of tics is controversial, PSP are nonetheless of considerable theoretical and clinical importance in TS, not least because they form the core component in many of the behavioural therapies that are currently used in the treatment of tic disorders. In this study, we investigated the brain structure correlates of PSP. Specifically, we conducted a whole‐brain analysis of cortical (grey matter) thickness in 29 children and young adults with TS and investigated the association between grey matter thickness and PSP. We demonstrate for the first time that PSP are inversely associated with grey matter thickness measurements within the insula and sensorimotor cortex. We also demonstrate that grey matter thickness is significantly reduced in these areas in individuals with TS relative to a closely age‐ and gender‐matched group of typically developing individuals and that PSP ratings are significantly correlated with tic severity.     

Frontal deficits differentiate progressive supranuclear palsy from Parkinson's disease

The clinical differentiation of progressive supranuclear palsy from Parkinson's disease can be challenging, due to overlapping clinical features and a lack of diagnostic markers. Abnormalities in cognitive function form part of the clinical spectrums of these diseases and distinctive cognitive profiles may be helpful in differentiating these diseases in the diagnostic period. A comprehensive neuropsychological test battery was administered to 12 patients with clinically diagnosed progressive supranuclear palsy and 12 patients with Parkinson's disease matched for age and disease duration. Effect size (Cohen's d) was calculated for cognitive tests that were significantly different between groups. Patients with progressive supranuclear palsy performed significantly worse than those with Parkinson's disease on measures of processing speed, verbal fluency, planning, verbal abstract reasoning, verbal memory, and made more perseverative responses on a set shifting task. Measures of executive function, manual dexterity and processing speed were most diagnostically useful (Cohen's d > 2.0) in differentiating between progressive supranuclear palsy and Parkinson's disease. These findings suggest that more severe and prominent ‘frontal’ cognitive deficits in patients with progressive parkinsonism would be helpful in predicting progressive supranuclear palsy rather than Parkinson's disease and these findings may contribute to the development of diagnostic criteria.     

自主任务转换中的重构和干扰

任务转换是研究执行功能的常用范式。任务转换通常伴随着转换代价：执行转换任务比重复任务的反应时更长、错误率更高。转换代价可能反映了任务设置重构(重构理论), 也可能表明任务之间存在干扰(干扰理论)。与任务线索范式相比, 自主任务转换范式更具生态效度, 而且不仅能获得转换代价这个传统结果, 还引入了任务选择比例、任务转换率等新指标, 其结果倾向于支持重构理论。此外, 新近研究指出自主任务转换可能也包含干扰的作用。未来, 应通过进一步改进实验范式等方法, 实现两大理论的融合。