交感神经系统在应激免疫调节中的作用

目前,越来越多的研究资料表明交感神经系统(SNS)参与了应激的免疫调节作用。有关研究主要集中在SNS与免疫系统间的解剖基础及相互作用、SNS参与应激的免疫调节作用的实验研究以及SNS与下丘脑-垂体-肾上腺轴（HPA）间的相互作用等几个方面。综合阐述这些研究结果,并着重分析SNS、应激与免疫系统间的相互作用及其机制     

Normische Gesetzeshypothesen und die wissenschaftsphilosophische Bedeutung des nichtmonotonen Schliessens

Normic Laws and the Significance of Nonmonotonic Reasoning for Philosophy of Science. Normic laws have the form ‘if A then normally B’. They have been discovered in the explanation debate, but were considered as empirically vacuous (§1). I argue that the prototypical (or ideal) normality of normic laws implies statistical normality (§2), whence normic laws have empirical content. In §3–4 I explain why reasoning from normic laws is nonmonotonic, and why the understanding of the individual case is so important here. After sketching some foundations of nonmonotonic reasoning as developed by AI-researchers (§5), Iargue that normic laws are also the best way to understand ceteris paribus laws (§6). §7 deals with the difference between physical and non-physical disciplines and §9 with the difference between normicity and approximation. In §8 it is shown how nonmonotonic reasoning provides a new understanding of the protection of theories against falsification by auxiliary hypotheses. §10, finally, gives a system- and evolution-theoretical explanation of the deeper reason for the omnipresence of normic laws in practice and science, and forthe connection between ideal and statistical normality. This revised version was published online in August 2006 with corrections to the Cover Date.     

对我国肝移植现状的系统化思考

阐述了我国肝移植的现状及新时期肝移植的新特点,用系统的观点分析了我国肝移植实施中存在的问题,提出了今后如何系统化发展我国肝移植事业的几点设想。     

美国贝克斯特测谎系统在我国法庭科学中的应用

该文简介了美国贝克斯特测谎系统的基本原理及其在我国法院的首次应用情况。在我国这一系统不仅被用于刑事案件,也被用于民事案件,实践证明,测谎技术起到了其他手段所起不到的作用,成为法院办案过程有力的辅助工具和支持系统。为使本系统具有更高的效力和适合中国的国情,需要对贝克斯特测谎系统进行修订,该文也介绍了有关修订和检验的情况。     

Referral Source Differences in Functional Impairment Levels for Children Served in the Comprehensive Community Mental Health Services for Children and Their Families Program

We report one of the first multi-site investigations into referral source variation in functional impairment for children with serious emotional disturbance served in systems of care settings. Baseline data collected as part of the national evaluation for the Comprehensive Community Mental Health Services for Children and Their Families Program was used to assess the comparability of functional status for children referred from traditional mental health versus non-mental health agencies. Results indicate that children referred from child welfare and family groups have significantly lower levels of overall dysfunction than those referred from mental health, while children referred from school and juvenile justice agencies have comparable levels. Clinical and research implications are discussed.     

Paul Tillich's Perspectives on Ways of Relating Science and Religion

Where do Paul Tillich's views of the relationship between religion and science fit in Ian Barbour's four classifications of conflict, independence, dialogue, and integration? At different levels of analysis, he fits in all of them. In concrete religions and sciences, some conflict is evident, but religion and science can be thought of as having parallel perspectives, languages, and objectives. Tillich's method of correlation itself is a form of dialogue. His theology of nature in “Life and the Spirit” (Part 4 of his Systematic Theology) fits the integration type. His strong “Two Types of Philosophy of Religion” (in Theology of Culture) is a latent natural theology. His system of the sciences is a form of synthesis, a type of integration.     

卫生系统绩效评估及其思考—《2000年世界卫生报告》的启示与思索

世界卫生组织在《2000年世界卫生报告－卫生系统：改进绩效》中,对191个成员国的卫生系统绩效进行了评估和排序。介绍了这一评估的框架和主要结果;提出对卫生系统绩效评估的启示与思考,认为我国应反思卫生改革绩效并客观地作出评价,为在新世纪促进卫生系统更好地发展和调整卫生改革目标作出明智的选择。     

中医药学将走向何方

由于中医缺乏形态学,中医没有成熟的科学实验,中医的诊断很难标准化、客观化,理论逻辑的致命弱点,理论体系难以重构,所以中医药学在很长一段时间内将保留下来之后,随着中医药学的理论体系的缺陷无法克服,原有的中医药体系必然解体,其中有部分内容融入现代医学。中医药学的归宿就是逐渐融入现代医学。     

Fronto-parietal mirror neuron system modeling: Visuospatial transformations support imitation learning independently of imitator perspective

Although the human mirror neuron system (MNS) is critical for action observation and imitation, most MNS investigations overlook the visuospatial transformation processes that allow individuals to interpret and imitate actions observed from differing perspectives. This problem is not trivial since accurately reaching for and grasping an object requires a visuospatial transformation mechanism capable of precisely remapping fine motor skills where the observer’s and imitator’s arms and hands may have quite different orientations and sizes. Accordingly, here we describe a novel neural model to investigate the dynamics between the fronto-parietal MNS and visuospatial processes during observation and imitation of a reaching and grasping action. Our model encompasses i) the inferior frontal gyrus (IFG) and inferior parietal lobule (IPL), regions that are postulated to produce neural drive and sensory predictions, respectively; ii) the middle temporal (MT) and middle superior temporal (MST) regions that are postulated to process visual motion of a particular action; and iii) the superior parietal lobule (SPL) and intra-parietal sulcus (IPS) that are hypothesized to encode the visuospatial transformations enabling action observation/imitation based on different visuospatial viewpoints. The results reveal that when a demonstrator executes an action, an imitator can reproduce it with similar kinematics, independently of differences in anthropometry, distance, and viewpoint. As with prior empirical findings, similar model synaptic activity was observed during both action observation and execution along with the existence of both view-independent and view-dependent neural populations in the frontal MNS. Importantly, this work generates testable behavioral and neurophysiological predictions. Namely, the model predicts that i) during observation/imitation the response time increases linearly as the rotation angle of the observed action increases but remain similar when performing both clockwise and counterclockwise rotation and ii) IPL embeds essentially view-independent neurons while SPL/IPS includes both view-independent and view-dependent neurons. Overall, this work suggests that MT/MST visuomotion processes combined with the SPL/IPS allow the MNS to observe and imitate actions independently of demonstrator-imitator spatial relationships.     

家庭研究新观点述评

文章概述了家庭研究观点的变化;概括并评论了家庭研究中三个新观点或新原则：双向互动原则,系统化原则和中介原则;提出了进一步开展家庭研究的一些设想。