Resting EEG in alpha and beta bands predicts individual differences in attentional blink magnitude

Accuracy for a second target (T2) is reduced when it is presented within 500 ms of a first target (T1) in a rapid serial visual presentation (RSVP) - an attentional blink (AB). There are reliable individual differences in the magnitude of the AB. Recent evidence has shown that the attentional approach that an individual typically adopts during a task or in anticipation of a task, as indicated by various measures, predicts individual differences in the AB deficit. It has yet to be observed whether indices of attentional approach when not engaged in a goal-directed task are also relevant to individual differences in the AB. The current studies investigated individual differences in the AB by examining their relationship with attention at rest using quantitative measures of EEG. Greater levels of alpha at rest were associated with larger AB magnitudes, where greater levels of beta at rest were associated with smaller AB magnitudes. Furthermore, individuals with more beta than alpha demonstrated a smaller AB effect than individuals with more alpha than beta. Our results suggest that greater attentional engagement at rest, when not engaged in a goal-directed task, is associated with smaller AB magnitudes.     

自闭症谱系障碍的早期筛查工具

基于35项实证研究, 遵循诊断准确性研究的质量评估(QUADAS-2)的循证程序对自闭症谱系早期预警特征筛查工具开展质量评估, 包括婴儿阶段(10个筛查工具, 159388人)、幼儿阶段(14项筛查工具, 11712人), 旨在为自闭症谱系风险的早期识别提供全面的理解。结果表明：幼儿阶段的筛查工具的分类准确性要高于婴儿阶段, 在婴儿阶段达到良好水平的筛查工具有M-CHAT-R/F、PDQ-1; 在幼儿阶段达到优秀水平的筛查工具有OERA、TIDOS。其中, “改良的幼儿自闭症检查表-有修订的后续随访” (M-CHAT-R/F)是目前最具潜力的自闭症谱系风险筛查工具之一。最后, 我们探讨了应用QUADAS-2评估研究质量的局限性, 强调需要规范工具的质量评估标准与进一步验证研究的必要性。     

Freud's psychoanalysis: A moral cure

That psychoanalytical treatment in its classical Freudian sense is primarily a moral or ethical cure is not a very controversial claim. However, it is far from obvious how we are to understand precisely the moral character of psychoanalysis. It has frequently been proposed that this designation is valid because psychoanalysis strives neither to cure psychological symptoms pharmaceutically, nor to superficially modify the behaviour of the analysand, but to lead the analysand through an interpretive process during which he gradually gains knowledge of the unconscious motives that determine his behaviour, a process that might ideally liberate him to obtain, in relation to his inner desires, the status of a moral agent. There resides something appealing in these claims. But it is the author's belief that there is an even deeper moral dimension applying to psychoanalytical theory and praxis. Freudian psychoanalysis is a moral cure due to its way of thematizing psychological suffering as moral suffering. And this means that the moral subject – the being that can experience moral suffering – is not primarily something that the psychoanalytical treatment strives to realize, but rather the presupposition for the way in which psychoanalysis theorizes psychological problems as such.     

Toward a New Attrition Screening Paradigm: Latest Army Advances

Managing and reducing attrition during the first term of enlistment is a continuing priority for the services. Over the past decade, attrition rates in the Army have averaged between 25% and 30% during first-term periods of enlistment. Historically, the services have relied on education credentials, with special emphasis on possessing a high school diploma, as a primary indicator of completion rates after enlistment and as a proxy for the ability to adapt to a military lifestyle. A primary purpose of this paper is to describe Army research to develop new indicators of adaptability to augment the current system based on education credentials. This work has focused primarily on noncognitive, personality measures and how such measures can be combined with other existing measures for attrition screening during enlistment processing. These advances represent a new paradigm that relies less heavily on education credentials and can provide a more comprehensive and inclusive approach. This new approach incorporates advances in testing methodology to make it more viable for use in large-scale, high-stakes testing applications.     

我国乡镇卫生资源二次配置模式探讨

长期以来,我国卫生资源配置城乡不均衡的局面比较严峻,大量优质卫生资源主要积聚在大中城市,而乡镇基层医疗机构的卫生资源比较稀缺。以增加政府财政投入,引入私人资本与第三部门力量等方式来提高农村卫生资源增量势必会遇到投入缓慢、资金不足、技术瓶颈等现实障碍。通过改革公立医院,调整城市卫生资源存量,把大中城市公立医院中的富余卫生资源以二次配置方式转移到农村卫生服务机构,是破解农村卫生资源存量不足、增长缓慢的困境,提高农村卫生服务能力和水平,改善农民就医问药问题的新途径。     

Second person thought

There are modes of presentation of a person in thought corresponding to the first and third person pronouns. This paper proposes that there is also thought involving a second person mode of presentation of another, which might be expressed by an utterance involving ‘you’, but need not be expressed linguistically. It suggests that co-operative activity is the locus for such thought. First person thought is distinctive in how it supplies reasons for the subject to act. In co-operative action there is first person plural intending and judging. So there is a way of thinking of another, when openly co-operating with him or her, which plays the distinctive role of giving reason for contribution to the co-operative activity. In slogan form, ‘you’ is ‘we minus I’. The way children learn to use second and third person pronouns is naturally explained on this view. Contrasting less sophisticated kinds of co-operative activity with more sophisticated forms, and considering some issues about common knowledge and common purpose, help to fill out the proposal.     

Effects of Hormone Replacement Therapy and Aging on Cognition: Evidence for Executive Dysfunction

ABSTRACT

The present study was designed to explore whether the frontal lobe hypothesis of cognitive aging may be extended to describe the cognitive effects associated with estrogen use in postmenopausal women. Postmenopausal estrogen-only users, estrogen + progesterone users, and non-users (60–80 years old), as well as young, regularly cycling women (18–30 years old) completed an item and source memory task. Since source memory is thought to rely more on executive processes than item memory, we hypothesized that aging and estrogen effects would be greater for source memory than for item memory. Neuropsychological tests explored whether the effects of aging and estrogen use were revealed on other tests of frontal lobe function. Results from the experimental task revealed greater aging and estrogen effects for source memory than for item memory, and neuropsychological results revealed aging and estrogen effects on a subset of tests of executive function. Women on estrogen + progesterone therapy did not outperform non-users, suggesting that the addition of progesterone to hormone therapy may mitigate the benefits induced by estrogen use alone. Overall, findings support the hypothesis that estrogen use may temper age-related cognitive decline by helping to maintain functions subserved by the frontal lobes.     

Age- and education-adjusted normative data for the Montreal Cognitive Assessment (MoCA) in older adults age 70–99

The original validation study for the Montreal Cognitive Assessment (MoCA) suggests a cutoff score of 26; however, this may be too stringent for older adults, particularly for those with less education. Given the rapidly increasing number of older adults and associated risk of dementia, this study aims to provide appropriate age- and education-adjusted norms for the MoCA. Data from 205 participants in an ongoing longevity study were used to derive normative data. Individuals were grouped based on age (70–79, 80–89, 90–99) and education level (≤12 Years, 13–15, ≥16 Years). There were significant differences between age and education groups with younger and more educated participants outperforming their counterparts. Forty-six percent of our sample scored below the suggested cutoff of 26. These normative data may provide a more accurate representation of MoCA performance in older adults for specific age and education stratifications.     

Effects of hearing and vision impairments on the Montreal Cognitive Assessment

Many standardized measures of cognition include items that must be seen or heard. Nevertheless, it is not uncommon to overlook the possible effects of sensory impairment(s) on test scores. In the current study, we investigated whether sensory impairments could affect performance on a widely used screening tool, the Montreal Cognitive Assessment (MoCA). Three hundred and one older adults (mean age = 71 years) completed the MoCA and also hearing and vision tests. Half of the participants had normal hearing and vision, 38% impaired hearing, 5% impaired vision, and 7% had dual-sensory impairment. More participants with normal sensory acuity passed the MoCA compared to those with sensory loss, even after modifying scores to adjust for sensory factors. The results suggest that cognitive abilities may be underestimated if sensory problems are not considered and that people with sensory loss are at greater risk of cognitive decline.