在综合基础上创新——鼠伤寒菌pla基因及其功能研究的思考

鼠伤寒菌pla基因及功能的研究从课题确立到取得结果整个过程,充分展现了综合研究方法在现代科学研究中的重要作用;在综合基础上的创新是科学研究成功的中心环节。     

Theory change in immunology part II: The clonal selection theory

This two-part article examines the competition between the clonal selection theory and the instructive theory of the immune response from 1957–1967. In Part I the concept of a temporally extended theory is introduced, which requires attention to the hitherto largely ignored issue of theory individuation. Factors which influence the acceptability of such an extended theory at different temporal points are also embedded in a Bayesian framework, which is shown to provide a rational account of belief change in science. In Part II these factors, as elaborated in the Bayesian framework, are applied to the case of the success of the clonal selection theory and the failure of the instructive theory.     

Green Keynesianism: Bringing the Entrepreneurial State Back in(to Question)?

Since the global financial crisis of 2007/8, proliferating calls for a Keynesian Green New Deal have cast the publicly (and environmentally) minded state as a necessary driver of technological innovation and social transformation, while, vice versa, innovation has moved to political centre-stage. The history and genesis of this particular Green Keynesian paradigm illustrate that some of its most high-profile proponents selectively and problematically frame twentieth-century Keynesianism and the ‘public good’. It is important to examine critically the calls for an ‘entrepreneurial state’ in which Green Keynesian ideas are mobilized in support of an agenda for continued and accelerated development of commercially focused, privately developed green technologies. The entrepreneurial state represents a neoliberal re-appropriation of Green Keynesianism, where dominant financial actors (in Silicon Valley, as opposed to on Wall Street) are tapped as the visionaries who can and should set our collective innovation agenda. Although there is a need for large-scale, coordinated techno-social efforts to address climate change, supporting ‘green’ innovation cannot simply be framed as maximizing ‘innovation’ while taking the ‘state’ for granted. Instead, it must entail a careful assessment of the specific trajectories of innovation being enabled and the underlying socio-natures that they maintain and promote. Science and technology studies (STS)-informed analysis allows, and compels, asking how socio-technological innovation and their constitutive power relations are crucially interrelated, making the reshaping of the state—still the primary institution and system of social relations of collective governance—a core but neglected political, technological and ecological project of our time, with a key role for STS.     

管理者权力距离对员工创造性观点产生与实施关系的调节作用

本研究考察了管理者的权力距离对于员工创造性观点产生与实施过程的调节作用。对170名企业员工和他们的直接主管的问卷调查结果表明：（1）管理者的权力距离对员工创造性观点的产生与实施的影响是不同的。管理者的高权力距离会抑制员工创造性观点的产生,但会促进员工创造性观点的实施。（2）管理者的高权力距离会促进员工创造性想法从产生向实施的转化。研究讨论了管理者的权力距离水平对于创新过程影响的实践意义。     

浅析当前临床科学决策的几个影响因素

随着循证医学在我国的发展和"医疗举证责任倒置"等相关法律的实施,我国临床医生在进行诊治决策时已逐步向临床科学决策迈进。而防御性医疗、不健全的医疗制度及相关法律等却严重影响着这一科学决策的转变过程。只有有效解决了导致干扰科学决策的各种社会影响因素,如扩大基本医疗保险的覆盖率,实施医疗风险保险制度,提高医务人员认知和职业素质,保障行医安全等,临床科学决策的真正落实就大有希望。     

真实创新预览、企业可雇佣性责任感与可雇佣型建言的关系

以59家科技型创业企业368名知识员工为被试,从新型员工—组织关系模式下个体认知的视角,探讨了企业真实创新预览与知识员工可雇佣型建言的关系,以及知识员工之企业可雇佣性责任感的中介作用。PLSSEM分析结果表明:(1)企业真实创新预览对知识员工的企业可雇佣性责任感各维度、可雇佣型建言具有显著正向影响;(2)知识员工的企业可雇佣性责任感各维度中,基于角色内胜任力提高、基于角色外能力提升2个维度对知识员工可雇佣型建言具有显著正向影响,并在企业真实创新预览与知识员工可雇佣型建言之间起部分中介作用;而基于个人生涯发展维度对知识员工可雇佣型建言的影响不显著,其在企业真实创新预览与知识员工可雇佣型建言之间也不起中介作用。     

创新氛围、创新效能感与团队创新：团队领导的调节作用

在团队层次探讨创新氛围、创新效能感以及团队领导对团队创新绩效的影响。对51个工作团队的研究结果表明, 团队创新氛围与团队创新绩效有显著的正向关系, 而团队创新效能感在这一关系中起到中介作用。同时, 引领创新的团队领导调节了创新效能感与团队创新绩效之间的关系, 团队领导越倾向于引领创新, 创新效能感与创新绩效之间的关系就越强, 经由创新效能感传导的创新氛围对创新绩效的效应也就越大。研究结果深刻揭示了创新氛围、创新效能感、创新领导和团队创新之间的关系。