放射影像检查中的医学伦理困境及对策分析

分析放射影像检查中面临的医学伦理困境及产生原因,包括医疗市场化、公立医院背离公益性、相关卫生法律法规不足、部分医务人员缺乏医学伦理学意识和知识、医务人员业务水平参差不齐等,并提出了相应的改进对策：强化公立医院公益性,坚持以患者为中心,合理、有序、有效地选用各种成像技术和检查方法,优化影像检查程序,避免过度检查和重复检查,加强法制与政策监管,充分保护患者的生命健康权、知情同意权、隐私权,提高医务人员医学伦理意识和业务水平,真正体现对患者的人文关怀。

     

Co-localisation of abnormal brain structure and function in specific language impairment

We assessed the relationship between brain structure and function in 10 individuals with specific language impairment (SLI), compared to six unaffected siblings, and 16 unrelated control participants with typical language. Voxel-based morphometry indicated that grey matter in the SLI group, relative to controls, was increased in the left inferior frontal cortex and decreased in the right caudate nucleus and superior temporal cortex bilaterally. The unaffected siblings also showed reduced grey matter in the caudate nucleus relative to controls. In an auditory covert naming task, the SLI group showed reduced activation in the left inferior frontal cortex, right putamen, and in the superior temporal cortex bilaterally. Despite spatially coincident structural and functional abnormalities in frontal and temporal areas, the relationships between structure and function in these regions were different. These findings suggest multiple structural and functional abnormalities in SLI that are differently associated with receptive and expressive language processing.     

自上而下注意控制的脑成像研究进展

自上而下的注意控制是调节人类各种认知活动的一种重要执行功能,本文从三个方面总结了该领域内脑成像研究的新进展：(1)自上而下注意控制的脑机制;(2)不同种类的注意控制脑机制的一致性;(3)自上而下的注意控制对其它皮层中神经活动的影响。     

EEG and fMRI agree: Mental arithmetic is the easiest form of imagery to detect

fMRI and EEG during mental imagery provide alternative methods of detecting awareness in patients with disorders of consciousness (DOC) without reliance on behaviour. Because using fMRI in patients with DOC is difficult, studies increasingly employ EEG. However, there has been no verification that these modalities provide converging information at the individual subject level. The present study examined simultaneous EEG and fMRI in healthy volunteers during six mental imagery tasks to determine whether one mental imagery task generates more robust activation across subjects; whether activation can be predicted from familiarity with the imagined activity; and whether EEG and fMRI converge upon the same conclusions about individual imagery performance. Mental arithmetic generated the most robust activation in the majority of subjects for both EEG and fMRI, and level of activation could not be predicted from familiarity, with either modality. We conclude that overall, EEG and fMRI agree regarding individual mental imagery performance.     

人类工作记忆的某些神经影像研究

采用神经影像技术研究人类工作记忆的脑机理是目前一个十分活跃的研究领域。研究表明存在负责不同信息加工的工作记忆系统 ,如词语工作记忆、空间工作记忆等 ,其中词语工作记忆主要由大脑左半球参与 ,空间工作记忆主要由大脑右半球参与。前额叶在工作记忆中的作用相当复杂 ,包括对记忆信息的注意和抑制、管理、整合等功能。合理巧妙的实验设计、多种研究手段的综合应用必将使人类工作记忆的脑机理得到充分阐明。     

Who is my Jung? Memories,Reflections, Prospects

The author describes his personal and professional journey in relation to the subject of the AJA 40^th anniversary conference, ‘Who is my Jung?’ The first part of the paper covers his early life and his attempt to bring together two opposing parts within him: valuation of a scientific approach, and an interest in the inner world, dreams and the paranormal. Discussion of his professional life follows, including his relationship with Gerhard Adler, past problems and splits within the Jungian community and the author's attempts to heal these. The value of both remembering and forgetting is questioned. This leads onto ideas that bring value and meaning to his work and life, and which bridge the inner divisions he felt in his early life: notably Jung's focus on applying scientific theory to the mystery of the psyche, his relational attitude (exemplified by the dialectical process and his interest in countertransference) and his theory of synchronicity. Recent discussion in Jungian writing has questioned the nature of synchronistic experiences and explored how they may emerge naturally from complex systems. The paper ends the author's continuing journey with two personal vignettes describing how meaning may emerge from the unconscious.     

The effects of sport dance on brain connectivity and body intelligence

Dancing is characterised by physical movement in accordance with rhythm perception. Twelve sport dancers and 12 age- and sex-matched young adults who had no dance experience (control group) were recruited. Body intelligence and brain activity were assessed in both groups using the Body Intelligence Scale (BIS) and resting state functional magnetic resonance imaging. BIS scores of dancers were higher than those of control subjects. The dancer group showed increased functional connectivity from the precentral gyrus to the right cingulate gyrus, right occipital fusiform gyrus, right inferior frontal gyrus, right medial frontal gyrus, left inferior frontal gyrus, right parietal postcentral gyrus, and right frontal lobe compared with control subjects. Sport dancers had increased body intelligence sensitivity compared with matched controls. In addition, the characteristics of dance, including physical movement in accordance with rhythm perception, might be associated with increased brain activity in the somatosensory and rhythm perception networks.     

Development and validation of the Movement Imagery Questionnaire for Children (MIQ-C)

The ability to perform movement imagery has been shown to influence motor performance and learning in sports and rehabilitation. Self-report questionnaires have been developed to assess movement imagery ability in adults, such as the Movement Imagery Questionnaire 3 (MIQ-3); however, there is a dearth of developmentally appropriate measures for use with children. To address this gap, the focus of this research was to develop an imagery ability questionnaire for children. This process involved adaptation of the MIQ-3 via: i) cognitive interviewing with twenty children, ii) validation with 206 children by examining its factor structure via multitrait-multi method confirmatory factor analysis, and iii) examination of test-retest reliability with 23 children. The findings of Study 1 led to changes to the wording of the questionnaire and modifications of the instructions to successfully adapt the MIQ-3 for children aged 7–12 years. The validation undertaken in Study 2 found that a correlated-traits correlated-uniqueness model provided the best fit to the data. Finally, test-retest reliabilities varied from fair (for external visual imagery) to substantial (for kinesthetic imagery). With respect to ease of imaging, no significant gender or age-group differences were noted. However, significant difference were found among the three imagery modalities (p < .001), with external visual imagery rated as easiest to image and kinesthetic imagery rated as the most difficult. Taken together, findings support the use of the MIQ-C for examining movement imagery ability with children.