Apodemus sylvaticus (LOXT) is a suitable mouse strain for testing spatial memory retention in the Morris water maze

Information on the difference in cognitive function between laboratory and wild-caught mice is anecdotal and this question has not been systematically studied. Moreover, studying a wild-caught mouse strain per se may add information to the repertoire of mouse strains available. We aimed to study spatial memory in a wild mouse strain (Apodemus sylvaticus, AS) as compared to two individual laboratory mouse strains.Male AS (n = 20), CD1 (n = 19) and C57BL/6J mice (n = 19), 12–14 weeks old, were used in the experiments. The Morris water maze (MWM) was used for determination of spatial memory and time spent in the target quadrant at time points 5 (D5) and 12 days (D12) was evaluated. During the acquisition phase latency to reach the platform and path length to reach the platform was evaluated.Following four training days on day 5 (D5), time spent in the target quadrant was highest in AS > CD1 > C57BL/6J (P < 0.006). On day 12 (D12), time spent in the target quadrant was significantly higher in AS than in both other strains (P < 0.001).All animals learned the task and during the acquisition phase, latency to reach the platform as well as path length decreased significantly in AS.It is concluded that the AS is the most suitable strain for the evaluation of spatial memory in the MWM and is presenting with memory retention superior to laboratory mouse strains CD1 and C57BL/6J.     

Treatment effectiveness of combined medication/behavioural treatment with chinese ADHD children in routine practice

BACKGROUND: The effectiveness of a combined methylphenidate/behavioural treatment (BT) versus methylphenidate-only for Chinese children with Attention-Deficit/Hyperactivity Disorder (ADHD) was tested in routine clinical practice in Hong Kong. METHODS: A randomized group comparison design was adopted with two treatment conditions (methylphenidate-only; methylphenidate/BT), which lasted for 6 months. There were four assessment time points (pre-treatment, post-treatment, and 6-month and 12-month follow-ups), using the Strengths and Weaknesses of ADHD Symptoms and Normal Behaviours (SWAN) Rating Scale. Parental attitude toward different treatment options of ADHD was also assessed at pre-treatment and post-treatment. Participants included 90 Chinese ADHD children (mean age=8 years, SD=.95). RESULTS: The combination of BT and a low-dose methylphenidate was significantly more effective than methylphenidate-only in reducing ADHD and ODD symptoms at post-treatment. At follow-ups, the benefits of the combined treatment were maintained, while the methylphenidate-only group caught up in improvement in ADHD symptoms. Parents in both treatment conditions showed improved attitude toward medication after the 6-month treatment phase, while their attitude toward BT was positive all along. CONCLUSIONS: This study supported the added benefits of BT, on top of medication, for Chinese ADHD children in routine practice with treatments conducted by regular medical and paramedical staffs.     

Racial/ethnic differences in Body Mass Index: the roles of beliefs about thinness and dietary restriction

The greater BMI of African American relative to Caucasian women is implicated in racial/ethnic disparities in health outcomes. The principal aim of the current study was to evaluate a theoretical account of racial/ethnic differences in BMI. Thin-ideal internalization, the perceived romantic appeal of thinness, dietary restriction, weight, and height were assessed via self-report measures on a sample of female undergraduates of African American (n = 140) and Caucasian (n = 676) race/ethnicity. Using structural equation modeling, support was obtained for the primary hypothesis that racial/ethnic differences in BMI are explained by Caucasian women's greater thin-ideal internalization and perceived romantic appeal of thinness, thereby resulting in greater levels of dietary restriction. Current findings illustrate the potential for racial/ethnic differences in sociocultural standards of appearance to influence racial/ethnic disparities in physical health, of which BMI is a marker, via effects on weight control behavior.     

Rawls on Human Rights: A Review Essay

In this essay, I first evaluate the conceptual analysis of human rights by Wilfried Hinsch and Markus Stepanians. Next I criticize Allen Buchanan’s claim that Rawls did not address basic human interests/capabilities theories of human nature. I argue Buchanan is doubly mistaken when he claims that John Rawls sought to avoid such theories because they are comprehensive doctrines. Then I evaluate David Reidy’s defense of Rawls, while questioning his efforts to show how Rawls’s list of human rights could be expanded. Finally, I accept James Nickel’s argument that Rawls has tied human rights too closely to intervention on their behalf. However, I reject his, and by implication Rawls’s, refusal to accept a two-tiered approach to human rights.     

Rethinking the Human Being in Light of Evolutionary Biology

Abstract : For the sake of its own enrichment and relevance, Christian anthropology today must be informed by what we are learning from the biosciences, including the theory of biological evolution. The two quite different paradigms of theology and biology should be seen as complementary to each other, with theology recognizing the biological foundation of human nature. This necessitates a repudiation of the traditional body/soul dualism and re‐conceptualizing the concept of soul as a metaphorical expression rather than a spiritual entity. It affirms the spiritual dimension of human life that relates us to God and neighbor. Biblical scholarship affirms this psychosomatic, holistic view of the human being.     

Interhemispheric interaction in word‐ and color‐matching of Kanji color words1

Abstract: The aim of the present study was to investigate the possibility that a shift toward a within‐hemisphere advantage would emerge when two stimulus items receive, respectively, different processing (vs. when they receive similar processing). Using right‐handed participants, we briefly presented two Kanji color‐word items as either within‐field or across‐fields. Viewers had to match the two items in terms of ink color (a color‐matching task) or word meaning (a name‐matching task). Each Kanji color word was presented with the same (congruent) or different (incongruent) ink color relative to the word meaning. Our results were twofold. First, a within‐field advantage appeared in the relatively easier color‐matching task, whereas an across‐field advantage tended to occur in the relatively harder name‐matching task. Second, in the word‐matching task an across‐field advantage appeared when both Kanji color words appeared in similar processing manners (both congruent or both incongruent), whereas a within‐field advantage occurred when processing of two Kanji items differed (one congruent and one incongruent). These results suggested that a shift toward a within‐hemisphere advantage occurs when two items are processed in respectively different ways.     

Failed Mirroring as a Cultural Phenomenon

Mirroring has failed when the reflection an individual receives is inaccurate or distorted. Though typically focused on parent–child interactions, mirroring and failed mirroring are also cultural phenomena. For women with dis/abilities, failed mirroring occurs when societal representations of dis/ability are reflected back rather than personal attributes. This essay suggests failed mirroring as a possible consequence of disabled women’s encounters with stares and analyzes one woman’s experience with a staring person that results in a temporary destabilization of self-knowledge and self-worth. Healthier relationships with others and the Divine have the potential of restoring or healing what has been lost or denied in such distortions.     

中国人集体主义的南北方差异及其文化动力

中国存在着集体主义的地区差异, 但学者对其内在动力机制尚未达成共识。我们认为儒家文化影响力的大小不容忽视, 受儒家文化影响越深的区域集体主义倾向越强。研究运用“亲亲性(loyalty/nepotism)”的内隐文化任务对来自27个省份的745名被试进行调查, 结果发现南方人对朋友更优待, 内外群体的心理界限更明显, 集体主义倾向更强。并探讨以儒家文化为代表的中原文化中心南迁对这一差异形成的影响及其未来研究方向。     

内隐序列学习意识的具身机制

内隐序列学习意识已有三类理论如全局工作平台理论、神经可塑性理论、新异刺激理论都忽略了身体感受的关键因素, 难以揭示意识产生的根本原因。具身意识理论和研究发现, 运动/情感镜像神经元系统及与自我、认知控制系统的交互, 是初级/高级意识产生的本源, 但未涉及内隐序列学习规则意识这个对人类学习认知至关重要的领域。内隐序列学习研究实质上已接近揭示其学习机制正是感知觉运动具身学习, 其意识机制很可能是感知觉运动/情感具身意识, 并且其意识加工脑区与具身意识脑区有关键重合。未来研究可采用Granger因果大脑网络技术证明内隐序列学习意识的具身本源, 并考察已有三类意识理论的具身基础, 以及探索意识影响因素的具身机制。     

Permission from an Input/Output Perspective

Input/output logics are abstract structures designed to represent conditional obligations and goals. In this paper we use them to study conditional permission. This perspective provides a clear separation of the familiar notion of negative permission from the more elusive one of positive permission. Moreover, it reveals that there are at least two kinds of positive permission. Although indistinguishable in the unconditional case, they are quite different in conditional contexts. One of them, which we call static positive permission, guides the citizen and law enforcement authorities in the assessment of specific actions under current norms, and it behaves like a weakened obligation. Another, which we call dynamic positive permission, guides the legislator. It describes the limits on the prohibitions that may be introduced into a code, and under suitable conditions behaves like a strengthened negative permission.