Route learning in Korsakoff's syndrome: Residual acquisition of spatial memory despite profound amnesia

Korsakoff's syndrome (KS) is characterized by explicit amnesia, but relatively spared implicit memory. The aim of this study was to assess to what extent KS patients can acquire spatial information while performing a spatial navigation task. Furthermore, we examined whether residual spatial acquisition in KS was based on automatic or effortful coding processes. Therefore, 20 KS patients and 20 matched healthy controls performed six tasks on spatial navigation after they navigated through a residential area. Ten participants per group were instructed to pay close attention (intentional condition), while 10 received mock instructions (incidental condition). KS patients showed hampered performance on a majority of tasks, yet their performance was superior to chance level on a route time and distance estimation tasks, a map drawing task and a route walking task. Performance was relatively spared on the route distance estimation task, but there were large variations between participants. Acquisition in KS was automatic rather than effortful, since no significant differences were obtained between the intentional and incidental condition on any task, whereas for the healthy controls, the intention to learn was beneficial for the map drawing task and the route walking task. The results of this study suggest that KS patients are still able to acquire spatial information during navigation on multiple domains despite the presence of the explicit amnesia. Residual acquisition is most likely based on automatic coding processes.     

Tool use in left brain damage and Alzheimer's disease: What about function and manipulation knowledge?

Tool use disorders are usually associated with difficulties in retrieving function and manipulation knowledge. Here, we investigate tool use (Real Tool Use, RTU), function (Functional Association, FA) and manipulation knowledge (Gesture Recognition, GR) in 17 left‐brain‐damaged (LBD) patients and 14 AD patients (Alzheimer disease). LBD group exhibited predicted deficit on RTU but not on FA and GR while AD patients showed deficits on GR and FA with preserved tool use skills. These findings question the role played by function and manipulation knowledge in actual tool use.     

西汉孟喜改列卦序中的哲学思想

孟喜为西汉象数易的创建人,其易学后人称之为“卦气”。卦气乃结合“学”与“术”成一结构庞大的思想体系。就学而言,乃承受先秦伏、文、孔三圣的易学精神;就术而言,乃用于当时流行的占断灾异、吉凶及祸福。然而后世易学界受儒学重经思想的影响,多轻视象数,以“术家”视孟喜。作者兹特提出孟氏卦气中对于六十四卦卦序之排列。并详作象敷之解析,以见孟氏易学实具有学术思想之价值。     

Probability of reciprocation in repeated prisoner's dilemma games

Both social cooperation and self‐control require reciprocation. In social cooperation situations a single person's cooperative act, if not reciprocated by others, would be unreinforced both immediately and in the long term. Similarly, a single act of self‐control (refusing a single cigarette, for example), if not followed up by other such acts, would also be unreinforced immediately and in the long term. The present experiments varied probability of reciprocation in a prisoner's dilemma‐like game that could resemble a social cooperation or a self‐control situation. Participants earned points by playing against a computer. The computer offered the participant a choice between 5 or 6 points (‘cooperation’ by the computer) or between 1 or 2 points (‘defection’ by the computer). The participant's choice of the lesser alternative (‘cooperation’) or the greater alternative (‘defection’) on the current trial led, respectively, to cooperation or defection by the computer on the next trial with a probability (probability of reciprocation, PR) which could vary. When PR was greater than 63%, consistent cooperation maximized the participant's earnings. When PR was less than 63%, defection maximized earnings. Three conditions were studied: PR signaled by spinners; PR unsignaled; PR unsignaled with participants believing that they were playing with another person, not the computer. With PR = 100% (‘tit‐for‐tat’) and PR = 50%, the modal participant maximized earnings under all three conditions. With PR = 75%, participants maximized earnings only when PR was signaled. These results indicate that differences between people's tendency to cooperate with other people (social cooperation) and their tendency to cooperate with their own future interests (self‐control) may lie in differences in subjective PR. Copyright © 2001 John Wiley & Sons, Ltd.     

Seek and ye shall find: test results are what you hypothesize they are

Expert clinicians were given batteries of psychodiagnostic test results (Rorschach, TAT, Draw-A-Person, Bender-Gestalt, Wechsler) to analyze. For half, a battery came along with a suggestion that the person suffers from Borderline Personality disorder, and for half, that battery was accompanied by a suggestion that he suffers from Paranoid Personality disorder. In Study 1, the suggestion was made indirectly, through a background story that preceded the test results. In Study 2, the suggestion was made directly, by the instructions given. The experts saw in the tests what they hypothesized to be there. In particular, the target diagnoses were rated higher when they were hypothesized than when they were not. Copyright © 1998 John Wiley & Sons, Ltd.     

A new rank correlation coefficient with application to the consensus ranking problem

The consensus ranking problem has received much attention in the statistical literature. Given m rankings of n objects the objective is to determine a consensus ranking. The input rankings may contain ties, be incomplete, and may be weighted. Two solution concepts are discussed, the first maximizing the average weighted rank correlation of the solution ranking with the input rankings and the second minimizing the average weighted Kemeny–Snell distance. A new rank correlation coefficient called τ_x is presented which is shown to be the unique rank correlation coefficient which is equivalent to the Kemeny‐Snell distance metric. The new rank correlation coefficient is closely related to Kendall's tau but differs from it in the way ties are handled. It will be demonstrated that Kendall's τ_b is flawed as a measure of agreement between weak orderings and should no longer be used as a rank correlation coefficient. The use of τ_x in the consensus ranking problem provides a more mathematically tractable solution than the Kemeny–Snell distance metric because all the ranking information can be summarized in a single matrix. The methods described in this paper allow analysts to accommodate the fully general consensus ranking problem with weights, ties, and partial inputs. Copyright © 2002 John Wiley & Sons, Ltd.     

Complexity effects on the children's gambling task

The children's gambling task (CGT [Kerr, A., & Zelazo, P. D. (2004). Development of “Hot” executive function: The children's gambling task. Brain and Cognition, 55, 148–157]) involves integrating information about losses and gains to maximize winnings when selecting cards from two decks. Both cognitive complexity and control (CCC) theory and relational complexity (RC) theory attribute younger children's difficulty to task complexity. In CCC theory, identification of the advantageous deck requires formulation of a higher-order rule so that gains and losses can be considered in contradistinction. According to RC theory, it entails processing the ternary relation linking three variables (deck, magnitude of gain, magnitude of loss). We designed two less complex binary-relational versions in which either loss or gain varied across decks, with the other held constant. The three closely matched versions were administered to 3–5-year-olds. Consistent with complexity explanations, children in all age groups selected cards from the advantageous deck in the binary-relational versions, but only 5-year-olds did so on the ternary-relational CGT.     

Lutheran Theology in Engagement with World Religions

Abstract : When Lutheran theology engages the world religions, it can offer valuable insights into God's word in action which could come from outside the church. In light of God's Word in action which is an indispensable part of Martin Luther's theology, the author draws special attention to Lutheran irregular theology in connection with a universal dimension of God's grace, theologia crucis, and God's reconciliation with the world. Thus, Lutheran theology is of pro‐Old Testament orientation in relationship with Israel, and also of dialogical and public character in dealing with the issue of religious pluralism.     

Establishing the feasibility of direct observation in the assessment of tics in children with chronic tic disorders

Behavior analysis has been at the forefront in establishing effective treatments for children and adults with chronic tic disorders. As is customary in behavior analysis, the efficacy of these treatments has been established using direct-observation assessment methods. Although behavior-analytic treatments have enjoyed acceptance and integration into mainstream health care practices for tic disorders (e.g., psychiatry and neurology), the use of direct observation as a primary assessment tool has been neglected in favor of less objective methods. Hesitation to use direct observation appears to stem largely from concerns about the generalizability of clinic observations to other settings (e.g., home) and a lack of consensus regarding the most appropriate and feasible techniques for conducting and scoring direct observation. The purpose of the current study was to evaluate and establish a reliable, valid, and feasible direct-observation protocol capable of being transported to research and clinical settings. A total of 43 children with tic disorders, collected from two outpatient specialty clinics, were assessed using direct (videotape samples) and indirect (Yale Global Tic Severity Scale; YGTSS) methods. Videotaped observation samples were collected across 3 consecutive weeks and two different settings (clinic and home), were scored using both exact frequency counts and partial-interval coding, and were compared to data from a common indirect measure of tic severity (the YGTSS). In addition, various lengths of videotaped segments were scored to determine the optimal observation length. Results show that (a) clinic-based observations correspond well to home-based observations, (b) brief direct-observation segments scored with time-sampling methods reliably quantified tics, and (c) indirect methods did not consistently correspond with the direct methods.