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101.
    
Abstract

The distinction between germline and somatic gene editing is fundamental to the ethics of human gene editing. Multiple conferences of scientists, ethicists, and policymakers, and multiple professional bodies, have called for moratoria on germline gene editing, and editing of human germline cells is considered to be an ethical “red line” that either never should be crossed, or should only be crossed with great caution and care. However, as research on germline gene editing has progressed, it has become clear that not all germline interventions are alike, and that these differences make a significant moral difference, when it comes to ethical questions about research, regulation, clinical application, and medical justification. In this paper, I argue that, rather than lumping all germline interventions together, we should distinguish between revising, correcting, and transferring genes, and I assess the consequences of this move for the ethics of gene editing.  相似文献   
102.
    
Literature has indicated the mixed impact of television content on the executive function (EF) of preschoolers. This study investigated the short‐term impact of TV fantastical events on children's EF performance and whether these impacts were different between boys and girls. This study included 143 preschoolers (Mage = 5.88 years, SDage = 0.32 years) and their parents. Participating children were randomly assigned to three groups to watch cartoons of high‐fantasy, mid‐fantasy, and low‐fantasy, and then requested to perform on a series of EF tasks. The results revealed the nonlinear pattern for the effects of fantasy on inhibitory control and cognitive flexibility. Specifically, children in the mid‐fantasy group did worst on inhibitory control and cognitive flexibility and no significant group differences were found in working memory. However, no conclusive evidence existed to prove the moderating role of gender on the relationship between fantastical events and EF. Finally, the implications of the findings and future directions are discussed.  相似文献   
103.
The Big Sleep     
ABSTRACT

This paper illustrates the link between creativity and psychotherapy as an art. Clinical examples are given first, followed by significant events that affected this therapist's creative activities. Then personal views of creativity arc described with the conclusion showing different aspects of creativity as applicable to psychotherapy.  相似文献   
104.
The value of cognitive science as a means of investigating psychodynamic theory and practice is discussed and the limitations of this approach are described. Research findings from cognitive science are drawn on to clarify the nature of memory, which is seen to be a mixture of reproduction and reconstruction and the concepts of true and false memory are explored in this light. The part played by implicit memory and internal working models in producing transference is also examined. New ways of conceptualizing fantasy, which describes it as another facet of internal working models, and the role of transgenerational transmission of attachment patterns in creating internal working models are explored. The nature of archetypes is considered in the light of cognitive science research and a minimalist model is proposed, in which they can be likened to image schemas, that is, primitive conceptual structures that exist in a form which can never be experienced directly or indirectly.  相似文献   
105.
This paper is a critical reconsideration of Freud's analysis (1907) of Wilhelm Jensen's novella Gradiva: A Pompeian Fantasy (1903). Freud's interest was aroused by the parallels between Jensen's presentation of dreams and Freud's model of dream formation just published in The Interpretation of Dreams (1900). Freud also acclaims Jensen's presentation of the formation and “cure” of his protagonist's delusion about a marble bas‐relief of a woman walking. This paper argues for the centrality of the phenomenon of fetishism, briefly considered but excluded from Freud's analysis. The fantasy of Gradiva as “the necessary conditions for loving” (Freud 1910, pp. 165–166) is also a key thesis of the essay, which makes use of the newly translated Freud–Jensen correspondence contained in this article's Appendix.  相似文献   
106.
107.
雌激素替代疗法的利与弊   总被引:5,自引:0,他引:5  
随着妇女社会地位的提高,以及人们对健康与生活质量要求的提高,绝经后雌激素替代疗法(HRT)日益成为人们关注的话题,越来越多的妇女选择在进入围绝经期后开始接受HRT,以改善因内源性雌激素分泌不足而引起的种种不适,确实提高了生活质量。但是,这种方法有增加子宫内膜癌、乳腺癌等其他疾病发病率的潜在危险,于是我们在临床应用时应该用辨证的眼光去看待它,试图抓住其主要矛盾,尽可能扬其利,避其害,以达到安全而有效地提高广大中老年妇女生活质量的目的。  相似文献   
108.
股骨头坏死(ONFH)是一种进展性和致残性疾病,保存自身股骨头是临床治疗所追求的最理想目标,早中期的治疗方案主要采用非手术疗法和保髋的姑息性手术,目前为止还没有一种治疗方法能达到理想的治疗效果。近年来,骨髓间充质于细胞(MSCs)移植治疗ONFH是目前研究热点之一,有望成为一种有效的治疗方法,晚期行人工髋关节置换术是唯一的和最佳的选择。因此,早期诊断,采用综合性治疗方案保全自身髋关节是治疗本病的主要方向。  相似文献   
109.
循证医学(evidence—based medicine,EBM)作为一门新兴的交叉学科越来越广泛地被用来进行临床评估和决策。人工椎间盘置换技术的发展为椎间盘退行性病变的治疗提供了符合现代医学模式的新方法。循证医学在人工椎间盘置换研究中的应用不仅有助于为其提供可信、有力的临床证据,而且有丰富的哲学内涵。  相似文献   
110.
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