多阶段增长模型的方法比较

多阶段增长模型（Piecewise Growth Modeling,PGM）可以解决发展趋势中具有转折点的情形,并且相对其他复杂的曲线增长模型,解释更简单.已有的统计方法主要通过多层线性模型和潜变量增长模型对多阶段模型进行估计.通过模拟研究,用HLM6.0和Mplus6.0对上述两种模型分别进行估计,结果发现在参数估计的精度上,两种估计方法没有差异,只是在犯一类错误的概率上后者略小.进一步通过对错误模型的探讨发现,在样本量小（n=50）,斜率变化小（△b=0.2）时,用线性模型拟合数据而非PGM所犯错误概率较小,整体拟合更佳.但随着样本的增加和斜率变化的增加,错误模型的犯错概率明显增大.故在实际应用中,为了能更好拟合数据,研究者应根据数据本身的情况选择恰当的模型.     

贝伐单抗治疗实体肿瘤的临床研究进展

血管内皮生长因子(vascular endothelial growth factor,VEGF)在肿瘤的发病机制中起着关键作用,其作为抗肿瘤治疗的重要靶点,已得到越来越多的关注.贝伐单抗(Bevacizumab,BEV)是一种血管内皮生长因子的单克隆抗体,是目前最受关注的分子靶向药物之一,自2004年经美国FDA批准上市以来,BEV已被用于多种实体肿瘤的治疗.本文就BEV关于治疗几类实体肿瘤的临床研究进展作一综述.     

A category mistake: why contemporary Australian religious education in Catholic schools may be doomed to failure

Assuming religious education to be the same as other subject areas of a Catholic school’s curriculum by, for example, applying the outcomes based philosophy and language of other subject areas to religious education renders a category mistake. A prominent notion in the work of metaphysical philosopher Gilbert Ryle, a category mistake arises when facts of one kind are presented as if they belong to another. This is significant. When Australian Catholic diocesan syllabus documents treat and describe religious education as being like other subjects comprising the curriculum, a category mistake is made, the effects of which may be damaging for student learning. Following an examination of relevant Church documents to describe its purpose, a brief analysis of contemporary Australian Catholic diocesan religious education syllabi (cases in point) indicates that a series of category mistakes have been made. These findings have significance in informing the development and refinement of theory, policy and practice in religious education.     

Religious support and psychosocial well-being among a religious Jewish population

The three subscales of the Religious Support Scale assess perceived support from a person’s religious community, religious leaders, and God. This three-factor structure was replicated in the current study with a sample of 277 religious Jewish persons residing in Israel. Hierarchical canonical analysis showed that, even after controlling for general social support, Religious Leader and God Support were related to lower emotional distress, Religious Leader and Religious Community Support contributed to a higher level of life satisfaction, and Religious Community and God Support contributed to the prediction of perceived health. Findings are discussed in terms of religious support’s generalizability as a psychosocial resource for persons of various faiths.     

The relationship between Quest religious orientation,forgiveness, and mental health

Little is known about how religious orientation, specifically Quest, relates to forgiveness. In addition, research on the relationship between Quest and psychological distress has yielded conflicting findings, possibly because previous studies have conceptualised Quest as a unidimensional construct. This study investigated how Quest and its recently recognised dimensions related to forgiveness and psychological distress. Participants (N?=?242) were undergraduates from a Midwestern Catholic university. They completed measures of Quest, forgiveness, and psychological distress. Results suggested that certain dimensions of Quest were better predictors of forgiveness (e.g., Tentativeness, Exploration, and Moralistic Interpretation) and distress (e.g., Change, Religious Angst, and Existential Motives). Importantly, results revealed that the same dimensions that were positively related to distress were negatively related to forgiveness. Further, the relationship between Quest and forgiveness was moderated by the perceived tolerance/open-mindedness level of the offender; it seems that individuals with a questing nature are less forgiving when the offender is perceived as less tolerant.     

Recognition of psychopathology with religious content by clergy members: a case vignette study

Clergy members (CMs) frequently offer support and counselling for people with mental health problems. The current study aims to obtain insight into the ability among CMs to recognise psychopathology and need for psychiatric treatment. A random sample of CMs (N?=?143) and a control sample of mental health professionals (MHPs, N?=?73), were compared as to their evaluations of four vignettes. CMs considered the psychiatric states to be related to religious or spiritual problems to a similar degree as they did for the non-psychiatric states. Sensitivity of CMs with regard to the need of psychiatric care for the psychiatric states was modest (66%) and differed significantly from MHPs (96%). Specificity of the CMs was 89%, which was significantly lower than the MHPs (97%). The CMs did recognise psychopathology with religious content but clearly to a lower extent than MHPs. Requests by CMs for education about recognising psychopathology may be considered as justified.     

Missed first appointments: Prevalence and associated factors in first-time attendees at an outpatient psychiatric clinic in Nigeria

In Nigeria, outpatient care forms the bulk of the psychiatric service. While there are no published data, empirical observations indicate that default may be high and exerting a huge toll on the cost of care. The aims were to determine the first-appointment default rate among newly seen outpatients in a psychiatric clinic and to identify factors associated with it. The study was a survey of all newly seen patients from 1 January 2006 to 31 January 2006, and who were given a follow-up appointment. A total of 223 new patients were seen. Of these, 151 (67.7%) turned up for their appointment, 61 (27.4%) defaulted, and 11 (4.9%) were referred. Defaulters were more likely to be Christians, younger in age, and in employment. On using correlation statistics, respondents’ religion and occupational status demonstrated a linear relationship and a significant association with follow-up attendance/non-attendance. The rate of non-attendance at first follow-up is of clinical concern, and the possible contribution of religion to this may be enormous. Clinicians and health policy makers need to be sensitive to this. The introduction of community psychiatric services and collaboration between orthodox and traditional/religious practitioners may help reduce default rates.     

Religiosity,happiness, health,and psychopathology in a probability sample of Muslim adolescents

The aim of the present study was to explore the religiosity associations with the self-rating scales of happiness, mental health, physical health, anxiety, and depression. A sample (N?=?6,339) of Muslim Kuwaiti adolescents was recruited. Their ages ranged from 15 to 18. They responded to four self-rating scales to assess religiosity, happiness, mental health, and physical health, as well as the Kuwait University Anxiety Scale, and the Center for Epidemiologic Studies-Depression Scale. Boys had higher mean scores on happiness, mental health, and physical health than did girls, whereas girls had higher mean scores on religiosity, anxiety, and depression. All the correlations were significant in both sexes. They were positive between each of the self-rating scales of religiosity, happiness, mental health, and physical health, and negative between these four rating scales and both anxiety and depression. A high-loaded and bipolar factor was disclosed and labelled “Religiosity and well-being vs. psychopathology.” In the stepwise regression, the main predictor of religiosity was happiness in both sexes.     

Mania precipitated by meditation: A case report and literature review

People attending various spirituality and self-development conferences outside the framework of organised religious groups (N = 204) were compared to norms from the general population and to members of New Religious Movements (NRMs) on the following measures: attachment to parents in childhood, adult attachment, need for closure, need for cognition, openness to experience, and quest religious orientation. Results indicated that these people, in comparison to the general population, share with NRM members similar cognitive (need for closure) and affective (insecure attachment in childhood) needs that seem to be addressed by spirituality. However, in comparison to NRM members, participants scored higher on measures reflecting self-growth, that is openness to experience and quest religious orientation, and lower on need for closure. These findings may be interpreted as indicating a desire to seek spirituality but to preserve autonomy. These people were called free-lance spiritual seekers.     

Spiritual advisors and old age psychiatry in the United Kingdom

This survey investigates the role and views of NHS spiritual advisors across the United Kingdom on the provision of pastoral care for elderly people with mental health needs. The College of Health Care Chaplains provided a database, and questionnaires were sent to 405 registered NHS chaplains/spiritual advisors. The response rate was 59%. Quantitative and qualitative analyses were carried out. Spiritual advisors describe their working patterns and understanding of their roles within the modern NHS, and their observations of the level of NHS staff awareness of the importance of spiritual issues in the mental health care of older adults. They provide insights into possible negative and positive perceptions of their roles at a service level, and contribute suggestions of topics relevant to shared education between pastoral care and clinical services. This survey further highlights ethical and operational dimensions at the point of integration of the work of spiritual advisors and multidisciplinary teams.