Longitudinal analysis of leisure-item preferences.

Twenty‐two individuals with developmental disabilities participated in two leisure‐item preference assessments, spaced approximately 16 months apart. Results showed (a) an overall increase in item contact across assessments for 13 participants and (b) at least some overlap across assessments in the five most highly ranked items for every participant. These results highlight individual differences in the stability of preference over time and suggest the need for research to identify the determinants of temporal shifts in preference.     

Air pollution, cognitive deficits and brain abnormalities: a pilot study with children and dogs

Exposure to air pollution is associated with neuroinflammation in healthy children and dogs in Mexico City. Comparative studies were carried out in healthy children and young dogs similarly exposed to ambient pollution in Mexico City. Children from Mexico City (n: 55) and a low polluted city (n:18) underwent psychometric testing and brain magnetic resonance imaging MRI. Seven healthy young dogs with similar exposure to Mexico City air pollution had brain MRI, measurement of mRNA abundance of two inflammatory genes cyclooxygenase-2, and interleukin 1 beta in target brain areas, and histopathological evaluation of brain tissue. Children with no known risk factors for neurological or cognitive disorders residing in a polluted urban environment exhibited significant deficits in a combination of fluid and crystallized cognition tasks. Fifty-six percent of Mexico City children tested showed prefrontal white matter hyperintense lesions and similar lesions were observed in dogs (57%). Exposed dogs had frontal lesions with vascular subcortical pathology associated with neuroinflammation, enlarged Virchow-Robin spaces, gliosis, and ultrafine particulate matter deposition. Based on the MRI findings, the prefrontal cortex was a target anatomical region in Mexico City children and its damage could have contributed to their cognitive dysfunction. The present work presents a groundbreaking, interdisciplinary methodology for addressing relationships between environmental pollution, structural brain alterations by MRI, and cognitive deficits/delays in healthy children.     

The effects of blocking mouthing of leisure items on their effectiveness as reinforcers

Leisure items are commonly used as reinforcers in behavior-analytic applications. However, a defining feature of autism is the occurrence of stereotypy, and individuals with autism often engage leisure items in a stereotyped manner. The opportunity for stereotyped interaction may be the only aspect of a contingent stimulus that makes it a reinforcer for appropriate behavior. Therefore, this study investigated the effects of blocking stereotyped reinforcer interaction on reinforcer efficacy for 2 children with autism. Results showed that blocking stereotypic reinforcer interaction did not influence reinforcer efficacy.     

Response-reinforcer contingency and spatially defined operants: testing an invariance property of phi

A chamber containing 72 response keys defining the circumference of a circle 1 m in diameter was used to examine the relation between differentiation of response location and a measure of response-reinforcer contingency known as the phi coefficient. A different target key was specified in each successive phase, and response location was differentiated with respect to the target. Criterional and noncriterional responses (i.e., responses "near" and "far" from the target) were defined using targeted percentile schedules to control the overall probability of each response class. By manipulating criterional (and, hence, noncriterional) response probability and the reinforcement probabilities conditional on each, a mathematical invariance property peculiar to phi in contingency analysis was examined. Specifically, diagonally interchanging cell frequencies in a 2 x 2 table relating criterional/noncriterional responses to reinforcement/nonreinforcement leaves phi unchanged. Hence, the degree of response differentiation predicted by phi remains unchanged under the four permutations implied by the various diagonal interchanges. This predicted invariance was examined under values of phi equal to .33, .58, and .82. Increasing phi generally increased the stereotypy of response location. Three of the permutations generated almost interchangeable performance at different phi values. The remaining permutation, however, generated functions relating response concentration to phi with slopes shallower than those obtained under the other permutations. This resulted from relatively higher levels of differentiation, compared to the other permutations, at low phi values. These data strongly suggest boundary conditions on the ability of phi to reflect completely the local processes that are indexed by phi at a molar level.     

The effect of logarithmic transformation on estimating the parameters of the generalized matching law

This study examined stimulus class membership established via stimulus-reinforcer relations. Mentally retarded subjects learned conditional discriminations with four two-member sets of visual stimuli (A, B, C, and D). On arbitrary-matching trials, they selected comparison stimuli B1 and B2 conditionally upon samples A1 and A2, respectively, and C1 and C2 conditionally upon B1 and B2, respectively. On identity-matching trials, they selected all stimuli as comparisons conditionally upon identical stimuli as samples. Throughout training, correct selections of A1, B1, C1, and D1 were followed by one reinforcer, R1, and those of A2, B2, C2, and D2 were followed by another, R2. Subsequent tests documented the formation of two four-member stimulus classes, A1-B1-C1-D1 and A2-B2-C2-D2. The class membership of the A, B, and C stimuli could have been based on equivalence relations that resulted from the arbitrary-matching training. D1 and D2 had never appeared on arbitrary-matching trials, however. Their class membership must have been based on relations with R1 and R2, respectively. Results thus confirm a previous finding that stimulus classes can be expanded via stimulus-reinforcer relations. They also define more precisely the potential nature of those classes and the conditions under which class membership can be established.