抗肿瘤药物心脏毒性的监测和治疗进展

许多临床常用的抗肿瘤药物均有不同程度的心脏毒性,常见的心血管并发症包括心力衰竭、心肌缺血、心律失常、高血压、低血压、血栓形成等。现就国内外近年对抗肿瘤药物心脏毒性的监测和治疗等方面的进展进行综述。     

Reading is believing: the truth effect and source credibility

Five experiments explored how source reliability influences people’s tendency to rate statements as more credible when they were encountered earlier (the truth effect). Undergraduates read statements from one reliable source and one unreliable source. Statements read multiple times were perceived as more valid and were more often correctly identified on a general knowledge test than statements read once or not at all. This occurred at varying retention intervals whether the statements originated from a reliable or unreliable source, when people had little memory for the statements themselves or their source, and when the discrediting information about the sources came either before or after reading the facts. While repetition aided recognition and source accuracy, both were unaffected by the reliability of the source. Consistent with the source monitoring framework, familiarity may create an illusion of truth for statements when people lack source-specifying cues, especially cues regarding the reliability of the source.     

Birth of the subject: the ethics of monitoring development programmes

NGO-based and rigorously monitored development programmes are bringing about important and positive socio-economic changes in the developing world. However, there are numerous instances of the employment of aggressive and grueling monitoring techniques which objectify the subject of development, the primary stakeholder, claiming development results as the successful achievement of goals of the donor or implementing organization. It is in this context that one can speak of an ethic of monitoring development programmes. The paper argues that such an ethic can be positively based on principles like empowering people through development work without hurting their sense of self-worth, the principle of trust and partnership and, negatively, never striving to objectify any person or people for the achievement of some objective, even if this objective is in itself honourable and desirable. The paper contends that if development is freeing the subject, the central player, to exercise their capability to live their life to the fullest, then development monitoring and development work in general has to enhance freedom, autonomy and openness.     

False recall in the Deese–Roediger–McDermott paradigm: The roles of gist and associative strength

Theories of false memories, particularly in the Deese–Roediger–McDermott (DRM) paradigm, focus on word association strength and gist. Backward associative strength (BAS) is a strong predictor of false recall in this paradigm. However, other than being defined as a measure of association between studied list words and falsely recalled nonpresented critical words, there is little understanding of this variable. In Experiment 1, we used a knowledge-type taxonomy to classify the semantic relations in DRM stimuli. These knowledge types predicted false-recall probability, as well as BAS itself, with the most important being situation features, synonyms, and taxonomic relations. In three subsequent experiments, we demonstrated that lists composed solely of situation features can elicit a gist and produce false memories, particularly when monitoring processes are made more difficult. Our results identify the semantic factors that underlie BAS and suggest how considering semantic relations leads to a better understanding of gist formation.     

Reactive and proactive control adjustments under increased depressive symptoms: Insights from the classic and emotional-face Stroop task

The current research investigated differences in reactive and proactive cognitive control as a function of depressive symptomatology. Three participant groups with varying symptom levels (Beck Depression Inventory–II, BDI–II score) completed both the classic and an emotional-face Stroop task separately under speed and accuracy instructions. All groups made equivalent speed–accuracy trade-offs independent of task, suggesting that proactive adjustments are unaffected by depressive symptoms. Additionally, groups made equivalent reactive control adjustments (Stroop effects, congruency sequence effects) in the classic Stroop task, suggesting that these reactive control adjustments are spared across a wide range of BDI–II scorers. In contrast, the high BDI–II group displayed a selective impairment in the resolution of conflict in the emotional-face Stroop task. Thus, while proactive control and many aspects of reactive control were unaffected by the level of depressive symptoms, specific impairments occurred when current task demands required the trial-to-trial regulation of emotional processing.     

Inconsistency effects in source memory and compensatory schema-consistent guessing

The attention–elaboration hypothesis of memory for schematically unexpected information predicts better source memory for unexpected than expected sources. In three source-monitoring experiments, the authors tested the occurrence of an inconsistency effect in source memory. Participants were presented with items that were schematically either very expected or very unexpected for their source. Multinomial processing tree models were used to separate source memory, item memory, and guessing bias. Results show an inconsistency effect in source memory accompanied by a compensatory schema-consistent guessing bias when expectancy strength is high, that is, when items are very expected or very unexpected for their source.     

A meta-analysis of the effects of electronic performance monitoring on work outcomes

Electronic performance monitoring (EPM), or the use of technological means to observe, record, and analyze information that directly or indirectly relates to employee job performance, is a now-ubiquitous work practice. We conducted a comprehensive meta-analysis of the effects of EPM on workers (K = 94 independent samples, N = 23,461). Results provide no evidence that EPM improves worker performance. Moreover, findings indicate that the presence of EPM is associated with increased worker stress, regardless of the characteristics of monitoring. Findings also demonstrate that organizations that monitor more transparently and less invasively can expect more positive attitudes from workers. Overall, results highlight that even as advances in technology make possible a variety of ways to monitor workers, organizations must continue to consider the psychological component of work.     

Further developments of the concept of fantasy

After the Isaacs' seminal work on the nature and function of unconscious phantasy (1948), several authors (mostly in the British Society) have reflected on the topic and tried to extend the concept of fantasy. In this paper I shall examine the contributions of Winnicott, Gaddini, Joseph and Anne Marie Sandler that aim at broadening this psychoanalytic concept. The authors that I have considered share a focus mostly on the early stages of child development. Both Winnicott and Gaddini belong to a line of thinking that explores the vicissitudes of the primary emotional development of the infantile self (in the mother‐infant relationship) involving the earliest processes of holding and bodily and kinaesthetic fantasy that form the bodily integrity of the person. The Sandlers focused mostly on the concept of the past unconscious understood as a place of primitive vicissitudes with a deficit in figuration where the process of repression is missing. The present unconscious phantasy (that is located in the here and now) has the function of rendering the past unconscious phantasy partly accessible; otherwise it would remain unknowable.     

3～5岁幼儿元认知监控发展特点的研究

该研究以北京市某幼儿园5个班98名幼儿为被试,利用拼图任务对其元认知监控能力的发展特点进行了探讨,结果发现:3～5岁幼儿在活动操作过程中,随着年龄的增长,注视目标的次数增多,完成任务的总时间在缩短,正确率在提高,但是悔步次数和停顿次数随着年龄变化的差异不显著;同时,注视目标的次数和停顿次数随着任务难度的变化而变化,表现出了一定的元认知监控能力。     

青少年父母监控现状研究

本研究从北京市两所普通中学的初一到高二年级中选取了1090名中学生为被试,采用问卷调查的方式,要求他们分别报告父亲和母亲的主、客观监控水平和监控手段(控制、沟通和搜寻),以探讨我国青少年父母监控的现状。经过(2)卡方检验、相关分析t、检验和方差分析,结果表明:(1)总体来讲,母亲在家庭里是青少年的主要监控者:母亲监控的客观水平高于父亲,并且母亲使用三种监控手段的情况均多于父亲;(2)女孩受到的父母监控超过男孩:母亲对女孩的客观监控水平高于男孩,并且母亲对女孩更多使用沟通手段;父母对女孩使用控制手段的情况超过男孩;(3)父母监控的年级差异并不明显,只有父母对初一学生会更多使用沟通手段;(4)父母对沟通手段和控制手段的使用都与客观监控水平呈正相关,但与主观监控水平呈负相关,而搜寻手段使用与监控水平之间的关系则跟沟通、控制手段相反;沟通手段对客观监控水平的正向预测力最强,搜寻手段对主观监控水平的正向预测力最强。