La psychothérapie assistée par la MDMA dans la prise en charge du syndrome de stress post-traumatique

Posttraumatic stress disorder (PTSD) is estimated to remain chronic and severe for 25–50% of patients despite psychotherapeutic treatment. Part of the reasons is that patients with PTSD can have difficulties in establishing a good therapeutical alliance with the therapist. Moreover, they often fail to re-think the content of the trauma without being overwhelmed by negative emotions and tend to rely on avoidance strategies and/or to abandon the therapy. MDMA (“ecstasy”) is a drug classified as an entactogen (en “within”, tactus “touch”, and gen “produce”), an amphetamine with psychedelic properties that possesses psychopharmacological properties to overcome these issues. Indeed, MDMA triggers the release of oxytocin, which favors the establishment of interpersonal relationship based on kindness and trust. Moreover, MDMA diminishes the activity of the amygdale, allowing patients to work on challenging memories with less fear and anxiety. Finally, MDMA may also provide access to meaningful spiritual experiences, release of tensions and a sense of healing on a non-verbal level that are not completely understood. But are viewed as important by patients. Today, there is no evidence that the use of MDMA in a clinical setting has bad neurologic, psychological or cognitive consequences. Results of phase II trials in the United States and Europe confirm that MDMA favors psychotherapy's outcome without severe adverse effects. Phase III trials are underway. The Multidisciplinary Association for Psychedelic Studies (MAPS) has published online a method proposal and trains therapists in MDMA-assisted psychotherapy.ConclusionFood and Drug Administration (FDA) and European Medicines Agency (EMA) could approve this therapeutic tool in the coming years.     

家庭社会经济地位对幼儿良好行为习惯的影响:父母教养方式与幼儿心理素质的中介作用

幼儿时期是培养个体良好行为习惯的重要关键期。以814名幼儿及其家长为研究对象,探讨家庭社会经济地位与幼儿良好行为习惯的关系,以及父母教养方式和幼儿心理素质的中介作用。结果表明：（1）家庭社会经济地位与幼儿良好行为习惯显著正相关;（2）父母教养方式与幼儿心理素质在家庭社会经济地位和良好行为习惯间起连续中介作用,且权威型教养方式与心理素质的链式中介作用显著高于专制型教养方式与心理素质的链式中介作用。因此,要促进幼儿养成良好行为习惯,应注重父母教养方式的选择与幼儿心理素质的培养。     

中国人社会善念的心理结构

为探究中国人社会善念的心理结构, 研究采用人格词汇法, 在开放调查收集的词汇中选取代表社会善念的心理词语, 确立了社会善念词库。通过两次探索性因素分析和验证性因素分析, 得到包含18个人格特质词的社会善念词汇评定量表和包含17项描述的社会善念自陈量表。研究表明, 中国人的社会善念是一种具有二阶四因素结构的人际特质, 二阶是指宜人特质和外倾特质, 四因素分别是善良尊重、谦和恭逊、包容理解和积极开放。     

错失恐惧对亲社会行为的影响

网络信息的纷繁复杂,让人们担忧因错失信息而导致自身的利益受损,本研究探讨这种现象的加剧对个体的亲社会行为的影响。本研究分别使用问卷法（研究1）和实验法（研究2）,探究错失恐惧对亲社会行为的影响以及在其过程中人际安全感的中介作用和基本心理需要满足的调节作用。结果发现：（1）个体的错失恐惧程度负向预测了其亲社会行为;（2）人际安全感在错失恐惧对亲社会行为的影响中起中介作用,高的错失恐惧水平会降低个体的人际安全感,从而减少个体的亲社会行为;（3）基本心理需要满足在错失恐惧对亲社会行为的负向预测作用中起调节作用,当个体的基本心理需要满足程度低的时候,错失恐惧对亲社会行为的消极影响显著增强。     

职场排斥对培训行业员工建言行为的影响——有调节的中介作用模型

研究采用问卷法,以安徽、天津的培训机构中的401名在职员工为研究对象,以组织支持感作为中介变量,以积极心理资本作为调节变量,从资源保存理论的视角探讨了职场排斥对员工建言行为的影响。研究结果表明:(1)职场排斥对员工的建言行为具有负向预测作用,职场排斥水平越高,其建言行为水平越低。(2)组织支持感在职场排斥与建言行为之间起中介作用,职场排斥通过组织支持感影响员工的建言行为。(3)组织支持感的中介作用受到积极心理资本的调节,积极心理资本会增强组织支持感的中介作用。     

自发性知觉经络反应中产生刺麻感和积极情绪的原因

自发性知觉经络反应(autonomous sensory meridian response,ASMR)是指在特定的视听刺激下,某些个体(ASMR敏感个体)在头皮后部、颈部乃至全身体验到一种令人极度愉快和放松的刺麻感的现象。其中,刺麻感的产生可能是个体大脑中负责感觉和肌肉运动的脑区高度激活引起的; 而与情绪和奖赏有关脑区的高度激活以及心率和呼吸频率的下降可能是产生愉快和放松感的重要原因。相比普通个体,ASMR敏感个体具有较高的神经质、共情特质、感觉受暗示性和特质正念。这可能说明ASMR敏感个体的感觉敏感性较高,情绪稳定性较弱,且比较关注自己身体的内外感受。这些个性特质可能导致ASMR敏感个体对某些视听刺激中所包含的一些感觉和情绪信息更加敏感,对其反应也更加强烈。目前,ASMR已经被用于抑郁,压力,失眠和慢性疼痛等的临床治疗以及商业广告之中。但ASMR可能会干扰个体的执行功能,在认知控制需求较高的情景下应尽量避免接触ASMR刺激。     

Conducting Prolonged Exposure for PTSD During the COVID-19 Pandemic: Considerations for Treatment

The unprecedented effects and duration of the COVID-19 crisis are likely to elevate the population’s level of anxiety due to psychological stress, economic hardship, and social isolation. This effect may be especially potent for individuals with preexisting mental health conditions, such as posttraumatic stress disorder (PTSD). Prolonged Exposure (PE) therapy is a highly effective treatment for PTSD across trauma-exposed populations, and has been implemented effectively via telehealth. Nevertheless, PE implementation via telehealth may require specific adaptations during the COVID-19 crisis due to public health mandates calling for sheltering in place and physical distancing. This paper discusses strategies for implementing PE for PTSD during the COVID-19 pandemic, which may also be applied to other situations in which physical distancing must be considered.     

Safety of micro-mobility: Riders’ psychological factors and risky behaviors of cargo TTWs in China

Cargo two- or three-wheeled vehicles (TTWs), as a new form of micro-mobility, have become a popular mode of urban cargo transportation in China. Cargo TTW riders’ psychological factors and risky behaviors lead to a number of accidents. A questionnaire is designed by comprehensively considering these factors and behaviors of cargo TTW riders that includes eleven risk factors to quantitatively analyze the risky behaviors based on structural equation modeling (SEM). One thousand three hundred nineteen participants reported using cargo TTWs on a questionnaire distributed across the country. The characteristics of riding behavior data are analyzed to verify the three-layer risk theoretical framework of “Psychological factors (Personality traits/specific factors) - Psychological acceptability of risks (confidence/perception/attitude) - Risky behaviors”. The results show that anger has a strong direct effect on riding violations, while normlessness and altruism have a direct effect on riding errors. Workload has a weak but direct effect on risky behaviors, and riding feedback has a weak and mixed effect. In addition, high-risk groups are identified by analysis of variance (ANOVA) with rider population attributes. These quantitative analyses can help guide safety countermeasures to mitigate accidents involving cargo TTWs.     

即刻消退缺损的原因分析及其神经生物学机制

即刻消退缺损(immediate extinction deficit, IED)是指在条件性恐惧习得后, 立即进行的消退训练不能长期抑制恐惧记忆的现象。IED可能与消退起始时的应激水平和事件分割等因素有关。在高应激水平下, 消退记忆的巩固受损导致IED; 而在中等或较低的应激水平条件下, 即刻消退有效但效果可能容易受事件分割的影响。IED的神经生物学机制涉及应激激活蓝斑去甲肾上腺素能系统, 去甲肾上腺素引起杏仁核基底外侧核(basolateral amygdala, BLA)过度兴奋, 然后BLA通过投射突触抑制在恐惧消退中起核心作用的内侧前额叶神经元的活动。未来研究应注意即刻消退缺损引起的长期后果, 并深入探讨如何优化即刻消退在临床上的应用。