Associations of Stress Exposures and Social Support With Long-Term Mental Health Outcomes Among U.S. Iraq War Veterans

The long-term mental health effects of war-zone deployment in the Iraq and Afghanistan wars on military personnel are a significant public health concern. Using data collected prospectively at three distinct assessments during 2003–2014 as part of the Neurocognition Deployment Health Study and VA Cooperative Studies Program Study #566, we explored how stress exposures prior, during, and after return from deployment influence the long-term mental health outcomes of posttraumatic stress disorder (PTSD), depression, anxiety disorders, and problem drinking. Longer-term mental health outcomes were assessed in 375 service members and military veterans an average of 7.5 years (standard deviation = 1.0 year) after the initial (i.e., “index”) Iraq deployment following their predeployment assessment. Anxiety disorder was the most commonly observed long-term mental health outcome (36.0%), followed by depression (24.5%), PTSD (24.3%), and problem drinking (21.0%). Multivariable regression models showed that greater postdeployment stressors, as measured by the Post-Deployment Life Events scale, were associated with greater risk of depression, anxiety disorders, and problem drinking. Anxiety disorder was the only outcome affected by predeployment stress concerns. In addition, greater postdeployment social support was associated with lower risk of all outcomes except problem drinking. These findings highlight the importance of assessing postdeployment stress exposures, such as stressful or traumatic life events, given the potential impact of these stressors on long-term mental health outcomes. This study also highlights the importance of postdeployment social support as a modifiable protective factor that can be used to help mitigate risk of long-term adverse mental health outcomes following war-zone exposure.     

急性疼痛与慢性疼痛对奖赏加工的影响及神经机制

疼痛和奖赏能够为个体提供不同的行为动机和主观价值体验,寻求奖赏和避免疼痛对于生存都很重要。疼痛可划分为急性疼痛和慢性疼痛,奖赏可区分为预期阶段的动机成分和体验阶段的享乐成分。奖赏对疼痛的抑制作用已经被广泛证实,但关于疼痛对奖赏的影响,目前的研究结果并不一致。因此需要进一步区分并探究急性疼痛与慢性疼痛对奖赏加工不同阶段的影响,分析两种疼痛对奖赏加工产生不一致影响的现象。这种现象出现的原因可能与急性疼痛向慢性疼痛转变过程中出现的奖赏加工能力缺陷有关。未来可以考虑从改善奖赏加工能力缺陷的角度进行检测和治疗,提前预防急性疼痛向慢性疼痛转变。     

工作记忆中转换加工的内源性准备 和外源性调节

考察工作记忆中转换加工的控制过程。采用“任务转换”范式,探究预知条件（实验一）和未预知条件（实验二）下的转换加工。结果发现：（1）任务重复与任务转换是两个不同的过程;无论是在预知条件还是未预知条件下都出现任务重复效应显著大于任务转换效应;（2）验证了转换加工包括内源性准备和外源性调节两个不同的加工过程, 内源性准备只是任务设置重建的一部分;（3）对先后呈现的两个任务（任务1—任务2 ：任务重复或任务转换）在预知重复、预知转换和未预知条件下,任务2对任务1的影响不同,存在前瞻性记忆效应。由此推断转换加工的心理过程是：在预知情况下,任务1呈现后即启动内源性准备,直到任务2呈现时,通过外源性调节最终完成任务转换;而在未预知情况下,只能依赖外源性调节来实现     

工作记忆在简单指数乘法等式判断中的作用

选择大学二年级数学系的学生作为被试,要求他们完成控制条件、语音任务、手动任务和随机间隔决策任务条件下的简单指数乘法等式判断任务,实验结果表明：（1）三种次级任务在真假等式判断的反应时上的干扰效应非常显著;（2）三种次级任务显著增加了假等式判断的错误率,但没有显著增加真等式判断的错误率。这说明,语音环路、视空间模板和反应选择成分参与简单指数乘法等式判断,而且真假等式判断具有不同的注意资源需求。     

12～20岁个体前瞻记忆的发展与影响因素的研究

以334名12～20岁个体为被试,采用两因素混合设计,探讨这一年龄阶段个体前瞻记忆的发展及影响因素。结果发现,被试前瞻记忆水平随年龄增长而提高,且在14～16岁发展最快;提高基于时间的前瞻记忆负载,会使前瞻记忆成绩降低;前瞻记忆与当前任务的完成呈负相关。表明前瞻记忆是一种策略加工过程。     

前瞻记忆的干扰效应：多重加工的证据

通过2个实验,对背景任务时间充裕和紧迫两种情况下的具体事件意向、类别事件意向、时间点意向、时间段意向四种前瞻记忆任务对背景任务的干扰效应进行考察。结果表明,在背景任务时间充裕情况下,类别事件意向对背景任务有干扰效应,具体事件意向、时间段意向和时间点意向都没有前瞻干扰效应;在背景任务时间紧迫情况下,时间点意向产生了干扰效应,具体事件意向、类别事件意向、时间段意向均无干扰效应。结果支持前瞻记忆的实现依赖多重加工的观点,时间性前瞻记忆并不一定比事件性前瞻记忆产生更大的干扰。     

Predictors of time-based prospective memory in children

This study identified age differences in time-based prospective memory performance in school-aged children and explored possible cognitive correlates of age-related performance. A total of 56 7- to 12-year-olds performed a prospective memory task in which prospective memory accuracy, ongoing task performance, and time monitoring were assessed. Additional tests of time estimation, working memory, task switching, and planning were performed. Results showed a robust relationship between age and prospective memory performance even after controlling for ongoing task performance. Developmental differences in time monitoring were also observed, with older children generally adopting a more strategic monitoring strategy than younger children. The majority of age-related variance in prospective memory task performance could be explained by cognitive resources, in particular planning and task switching. In contrast, no further independent contribution of time estimation was observed. Findings are in line with the development of strategic behavior, as well as executive functioning, in school-aged children.     

前瞻记忆意向后效应的加工机制:来自眼动的证据

基于重复前瞻记忆目标范式和视觉搜索范式,采用多种类型刺激呈现的眼动测量方式考察前瞻记忆意向后效应的加工机制。研究采用2（条件）×5（刺激类型）的混合实验设计,显著条件下前瞻记忆目标为红色,非显著条件下前瞻记忆目标和其他字母的颜色均为白色,背景为黑色。结果显示,显著和非显著条件下前瞻记忆完成阶段中对原前瞻记忆目标的反应时慢于控制条件,而且前瞻记忆目标在进行中任务目标之后的反应时慢于进行中任务目标之前的刺激类型。另外,非显著条件下,前瞻记忆目标在进行中任务目标之前和之后的眼动数据没有差异;显著条件下的注视点数量多于控制条件,前瞻记忆目标在进行中任务目标之后的注视点数量多于进行中任务目标之前的刺激类型。结果说明,前瞻记忆任务完成以后,在随后的阶段中遇到原前瞻记忆目标时被试会投入认知资源对其进行抑制,支持抑制加工。