Systems marketing: a new operating model for pharmaceutical marketing

This paper introduces a new model for marketing based on systems design. Adaptive tactical systems are featured as a novel commercial approach that enables ROI to be measured holistically, and serves as a comprehensive strategy for progressive integration, accommodating new marketing components, on‐demand technologies, and business ideas as they emerge and are added to the same containing whole. Initially applied to the pharmaceutical industry, the paper details the design and evolution of a brand module, a tactical system focused specifically on harvesting top‐line sales from primary care brands in a middle market of the United States. Copyright © 2005 John Wiley & Sons, Ltd.     

Early electro-cortical correlates of inspection time task performance

The concept of general intelligence (g) summarizes the well established finding that scores on separate cognitive tasks are positively correlated, indicating a trait common to many aspects of information processing. Inspection time is a well-established correlate of IQ, where those of a higher IQ can correctly identify a briefly presented stimulus with a greater level of accuracy than those of a lower IQ. This study used two age-matched samples, selected on the basis of their scores on Raven's Advanced Progressive Matrices from the undergraduate population of Bangor University. In order to address the confound of inspection time and IQ of previous ITT-ERP research, each participant of the presented study performed an IT task with the same five levels of stimulus duration while undergoing 64-channel EEG recording. The high IQ group made significantly fewer errors at each level of stimulus duration and exhibited a significantly larger N1 response. N1 latency and other ERP components did not distinguish the two IQ groups. Given the specificity of ERP group differences to the N1, the results of the present study suggest that the link between IT performance and g is attributable to individual differences in directing attention to a spatial region.     

The effect of Multi Convergent Therapy on the psychopathology,mood and performance of Chronic Fatigue Syndrome patients: A preliminary study

Objectives: Multi Convergent Therapy combines approaches such as Cognitive Behaviour Therapy and Graded Exercise Therapy in an holistic treatment of Chronic Fatigue Syndrome. Initial follow‐up data showed that patients were benefiting from this individualised form of therapy. The objective of the present study was to evaluate this Multi Convergent approach, developed at a specialised Chronic Fatigue Syndrome Outpatient clinic in Cardiff, and compare it to Relaxation Therapy and control groups using multiple outcome measures. Design: Thirty‐five participants fitting the Centre for Disease Control criteria for Chronic Fatigue Syndrome were recruited from two outpatient clinics and members of our existing patient panel. Patients were assigned to Multi Convergent Therapy (N=12), Relaxation Therapy (N=14) or recruited as controls (N=9). Methods: Each patient completed a battery of mood and performance tasks along with comprehensive set of questionnaires at baseline, post‐treatment and at six‐month follow‐up. These measures had been validated in previous studies on untreated patients and matched healthy controls. Results: Patients attending the Multi Convergent Therapy clinic showed statistically significant improvements in many of our measures. Most importantly we have produced data indicating that Multi Convergent Therapy provides improvements in objective measures of psychomotor performance and cognition. Discussion: The outcomes of this small study are encouraging. Multi Convergent Therapy has not only produced results indicating significant improvements in standardised questionnaire based measures but also in objective cognitive performance tasks. The next step would be to assess Multi Convergent Therapy at the primary medical care level, with a greater number of patients to further evaluate its efficacy as a treatment for Chronic Fatigue Syndrome.     

Force irradiation effect of kinesiotaping on contralateral muscle activation

We aimed to determine the force irradiation effect of kinesiotaping (KT) on contralateral muscle activity during unilateral muscle contraction. Forty healthy (26 females, 14 males) subjects were divided into two groups: KT and control groups. KT was applied on the biceps brachii at the contralateral limb (non-dominant limb) in the KT group, whereas no taping was applied to the control group. All participants performed unilateral isometric, concentric, and eccentric contractions with their dominant upper limbs (exercised limb) by means of an isokinetic dynamometer, while the contralateral limb was in the resting condition, neutral position, and motionless during the testing procedure. During the exercise, contralateral biceps brachii muscle activity was recorded by surface electromyography (EMG). To quantify the muscle activation, EMG signals were expressed as a percentage of the maximal isometric voluntary contraction, which is referred to as %EMG_max. The KT group showed significantly higher %EMG_max in the biceps brachii compared to the control group at the contralateral limb during the isometric, concentric, and eccentric contractions (p = 0.035, p = 0.046, and p = 0.002, respectively) The median values of the contralateral muscle activity were 2.74 %EMG_max and 6.62 %EMG_max during the isometric contraction for the control and KT groups, respectively (p = 0.035). During the concentric contraction, the median values of the contralateral muscle activity were 1.61 %EMG_max and 9.39 %EMG_max for the control and KT groups, respectively (p = 0.046). The median values of the contralateral muscle activity were 4.49 %EMG_max and 22.89 %EMG_max for the eccentric contraction for the control and KT groups, respectively (p = 0.002). In conclusion, KT application on the contralateral limb increased the contralateral muscle activation in the biceps brachii during the unilateral isometric, concentric, and eccentric contractions.     

Mapping the Terrain of a Foucauldian Ethics: A Response to the Surveillance of Schooling

Educators find themselves in the midst of arising tide of urban school reform marked byevermore centrally designed and monitoredsystems of accountability. In response to thislooming high-stakes gaze of surveillance, thisessay offers an ethics of educationalleadership predicated upon taking up thechallenge of creatively and courageouslyauthoring one's ethical self. It seeks tocontribute to mapping an ethical terrain whichcan support the production of pedagogicalpractices, initiatives, and agendas asdistinctive, bold responses to theproliferation of one-dimensional,technicist-driven efforts which narrowlycalculate and assess student learning, teacherwork, school effectiveness, and which offeranemic, foreclosed readings of a possiblefuture. My claim is that a consideration ofFoucault's ethics draws us closer torecognizing what such a project would mean andask of the educator as leader.     

An Examination of the Effects of Stress Management Training for Japanese College Students of Social Work

The purpose of the present study was to examine the effects of a stress-management program for college students of social work on their perception of mental stress and stress-coping strategies. Students in a stress-management group received progressive muscle training, cognitive-behavioral skills training, and assertion training for 14 weeks. Their life events, stress symptoms, and stress-coping skills (active and passive coping skills), evaluated on the first and last days of program, were compared with those of a control group. The effect of the participants' trait anxiety on those variables was also examined. Because the stress-management program in the present study focused on coping strategies, it was expected that the students' coping skills would change. The results showed that passive coping skills of students in the stress-management group had decreased after the program.     

Treating Speech Anxiety in Youth: A Randomized Controlled Microtrial Testing the Efficacy of Exposure Only Versus Exposure Combined With Anxiety Management Strategies

CBT for anxious youth usually combines anxiety management strategies (AMS) with exposure, with exposure assumed to be critical for treatment success. To limit therapy time while retaining effectiveness, one might optimize CBT by restricting treatment to necessary components. This study tested whether devoting all sessions to exposure is more effective in reducing speech anxiety in youth than devoting half to AMS including cognitive or relaxation strategies and half to exposure. After a 6-week waitlist period, adolescents with speech anxiety (N = 65; age 12–15; 42 girls) were randomized to a 5-session in-school group-based CBT training consisting of either (1) exposure-only (EXP+EXP) or (2) cognitive strategies followed by exposure (COG+EXP) or (3) relaxation strategies followed by exposure (REL+EXP). Clinical interviews, speech tests, and self-report measures were assessed at pretest, posttest, and follow-up. For all conditions (a) the intervention period resulted in a stronger decline of speech anxiety than waitlist period; (b) there was a large sized reduction of speech anxiety that was maintained at six-week follow-up; (c) there was no meaningful difference in the efficacy of EXP+EXP versus COG+EXP or REL+EXP. These findings suggest that devoting all sessions to exposure is not more effective than combining exposure with AMS. AMS appeared neither necessary for CBT to be effective, nor necessary for youth to tolerate exposure. This indicates that CBT can be optimized by restricting treatment to exposure.     

Investigating the effects of a virtual reality-based stress management programme on inpatients with mental disorders: A pilot randomised controlled trial

This study aimed to examine the effects and feasibility of a virtual screen-based stress management programme (V-DESSERTS) on inpatients with mental disorders. A single-blinded, pilot randomised controlled trial was conducted in a tertiary hospital in Singapore. Convenience sampling was used and participants were randomised into either the intervention group or the waitlisted control group (WL). The intervention group received individual-based, twice-daily sessions of the programme. Each session comprised education and virtual screen-based relaxation practice. Data were collected through self-reported questionnaires and physiological measures. The intervention group showed a significant increase in perceived relaxation and knowledge in comparison with the WL group. However, inconclusive results were observed on subjective and objective stress. The findings in this study indicated that the V-DESSERTS programme is feasible to be implemented for patients with schizophrenia, depression and bipolar disorders.     

The effects of four days of intensive mindfulness meditation training (Templestay program) on resilience to stress: a randomized controlled trial

The interest in mindfulness meditation interventions has surged due to their beneficial effects in fostering resilience and reducing stress in both clinical and non-clinical populations. However, the relaxation benefits that may occur while practicing mindfulness meditation and long-term benefits of these interventions remain unclear. Fifty-one participants were recruited and randomized into the experimental and control groups, which underwent 4 days of Intensive Meditation (Templestay program, n = 33) and Relaxation (Control, n = 18), respectively. The self-report measures of Cognitive and Affective Mindfulness Scale-Revised (CAMS) and the modified Korean version of the Resilience Quotient Test (RQT) were administered pre-, post- and 3 months after the intervention to measure participants’ levels of mindfulness and resilience. Participants in both the Templestay program and Control groups showed significant increases in their scores on CAMS and RQT after completing the program. During the 3-month follow-up, a significant interaction effect of the intervention method and time was revealed for the individuals’ CAMS and RQT scores. Our findings support the hypothesis that while relaxation practices may have certain stress reduction effects, the effects are predominantly mediated by the mindfulness meditation practice. Furthermore, the long-term benefits of increased resilience observed in the Templestay program group suggest that the practice may be a possible treatment strategy in clinical populations, such as patients with depression and anxiety.     

An inventory for assessing interpersonal communication competence of college students

We have developed and validated a new Interpersonal Communication Competence Inventory (ICCI) for college students. Study 1 describes the development of the ICCI and results of an exploratory factor analysis of data from 1336 Chinese students, which identified a four-factor model with reasonable internal consistency. Study 2 describes results of a confirmatory factor analysis of data from 593 Chinese students, which cross-validated the four-factor model as well as supporting the validity of the overall scale. Taken together, these results suggest that the ICCI is a psychometrically valid measure of interpersonal communication competence of college students.