对肾移植输血问题的思考

就肾移植受者输血的几个问题进行了回顾和探讨。提出肾移植受者输血应该考虑的问题有：如何权衡输血对肾移植受者的有益作用与输血风险,输血医学的发展如何为肾移植提供更有力的保障,应该深入探讨输血有益于肾移植的机制,推进供者特异性输血在我国的应用。     

Competing stimulus assessments: A systematic review

The current review summarizes the literature on competing stimulus assessments (CSAs). CSAs are pretreatment assessments designed to systematically identify stimuli that reduce problem behavior (PB), ostensibly through reinforcer competition or substitution. We report on the participant characteristics, outcomes, and predictive validity of published CSAs that included (a) no-stimulus control trial(s), (b) test trials during which each stimulus was available singly and noncontingently, and (c) measurement of PB and stimulus engagement or contact. Results showed that CSAs have broad utility across a variety of topographies and functions of PB. In the majority of CSA applications for which extended analyses, or validations, were performed, stimuli shown to reduce PB during the CSA produced similar reductions during extended analysis. This was the case regardless of topography or function of PB, or whether the stimuli were assumed to be “matched” to the stimulation thought to be produced by PB. Implications for future research are discussed.     

In search of the ‘Aha!’ experience: Elucidating the emotionality of insight problem‐solving

Although the experience of insight has long been noted, the essence of the ‘Aha!’ experience, reflecting a sudden change in the brain that accompanies an insight solution, remains largely unknown. This work aimed to uncover the mystery of the ‘Aha!’ experience through three studies. In Study 1, participants were required to solve a set of verbal insight problems and then subjectively report their affective experience when solving the problem. The participants were found to have experienced many types of emotions, with happiness the most frequently reported one. Multidimensional scaling was employed in Study 2 to simplify the dimensions of these reported emotions. The results showed that these different types of emotions could be clearly placed in two‐dimensional space and that components constituting the ‘Aha!’ experience mainly reflected positive emotion and approached cognition. To validate previous findings, in Study 3, participants were asked to select the most appropriate emotional item describing their feelings at the time the problem was solved. The results of this study replicated the multidimensional construct consisting of approached cognition and positive affect. These three studies provide the first direct evidence of the essence of the ‘Aha!’ experience. The potential significance of the findings was discussed.     

Within‐subject analysis of a prevention strategy for problem behavior

Although decades of research on functional analysis methodology have identified common contingencies that maintain problem behavior and effective interventions, relatively little research has been conducted on strategies to prevent the initial development of problem behavior. We conducted a 2‐part case study, the purposes of which were to illustrate the use of sensitivity tests as the bases for intervention (Study 1) and subsequently to assess the efficacy of a prevention strategy using a single‐subject design (Study 2). Results showed that the sensitivity tests identified establishing operations that may set the occasion for the development of problem behavior and that interventions based on differential reinforcement prevented increases in the severity of problem behavior relative to untreated and control baselines. Benefits and limitations to this individualized approach to prevention are discussed.     

An integrated model for guiding the selection of treatment components for problem behavior maintained by automatic reinforcement

We evaluated the usefulness of 2 assessments to guide treatment selection for individuals whose prior functional analysis indicated that automatic reinforcement maintained their problem behavior. In the 1st assessment, we compared levels of problem behavior during a noncontingent play condition and an alone or ignore condition. In the 2nd, we assessed participants’ relative preferences for automatic reinforcement and social reinforcers in a concurrent‐operants arrangement. We used the results of these 2 assessments to assign 5 participants to a treatment based on noncontingent access to social reinforcers or to a treatment based on differential access to social reinforcers. We conducted monthly probes with the participants over 10 to 12 months to evaluate the effects of the treatment procedures. All participants showed reductions in problem behavior over this period.     

Individual and combined effects of noncontingent reinforcement and response blocking on automatically reinforced problem behavior

Noncontingent reinforcement (NCR) and response blocking are 2 common interventions for problem behavior maintained by automatic reinforcement. We implemented NCR and blocking with 1 boy and found this combined intervention to be effective at decreasing high rates of automatically reinforced pica. With another child, we compared the effects of blocking alone to the combined intervention. With the third child, we compared NCR alone and blocking alone to the combined intervention. Results showed that the combined intervention was effective at reducing automatically reinforced problem behavior while moderate to high levels of item engagement maintained. When evaluated individually, neither NCR nor blocking was sufficient to reduce problem behavior to clinically significant levels.     

Assessment and treatment of problem behavior maintained by mand compliance

We modified functional analysis procedures to include a condition in which we reinforced problem behavior by complying with a child's mands. After identifying compliance with mands as a reinforcer, we evaluated the efficacy of a token system with a response‐cost contingency and incorporated discriminative stimuli to signal when mands would be reinforced. The token system with response cost effectively reduced problem behavior. Similar procedures may be beneficial when continuous adult compliance is not possible, when adults want to control when they will comply with the child's mands, or to build a child's tolerance for adult‐directed situations.     

关于假设检验的争议:问题的澄清与解决

对传统的假设检验作为心理学实验的数据分析工具的评价涉及两个标准:首先是它是否合法,其次是它是否有用。置于频率学派统计学框架中的传统假设检验在逻辑上实际上是合法的;但它在效用性方面则有着备择假设不可证伪以及只能提供定性结论这两方面的缺陷。置信区间能够集中地改进和弥补这些缺陷。对传统假设检验使用中错误的澄清也使得研究者们开始重视PSI问题,这使得心理学实验的设计和数据分析从关注总体转向关注个体。     

Cognitive events in a problem-solving task: a qualitative method for investigating interactivity in the 17 Animals problem

Outside the cognitive psychologist's laboratory, problem-solving is an activity that takes place in a rich web of interactions involving people and artefacts. This interactivity is constituted by fine-grained action–perception cycles, and it allows a reasoner's comprehension of the problem to emerge from a coalition of internal and external resources. Taking an ecological approach to problem-solving, this paper introduces a qualitative method, Cognitive Event Analysis, for studying the fine-grained interactivity between a problem-solving agent and his/her environment. To demonstrate the potential of this method, it is used to study a single subject solving the so-called 17 Animals problem using a material model. The fine-grained procedure allows tracking the solution to a serendipity that was brought about because of the participant's aesthetic considerations and a change in her perceptual figure-ground configuration. While a qualitative single-case method cannot prove specific models of problem-solving, it questions prevalent mentalist models, and it generates new hypotheses on insight problem-solving, because it allows the researcher to attend to outliers and to variability on a fast and fine-grained between-measurement timescale.