The Nature and Significance of Behavioural Genetic Information

In light of the human genome project, establishing the genetic aetiology of complex human diseases has become a research priority within Western medicine. However, in addition to the identification of disease genes, numerous research projects are also being undertaken to identify genes contributing to the development of human behavioural characteristics, such as cognitive ability and criminal tendency. The permissibility of this research is obviously controversial: will society benefit from this research, or will it adversely affect our conceptions of ourselves and each other? When assessing the permissibility of this research, it is important to consider the nature and deterministic significance of behavioural genetic information. Whilst todate there has been much discussion and debate about the properties of genetic information per se and genetic determinism, this has not been applied to behavioural genetic research and its ethical implications. Therefore, this paper elucidates how behavioural genetic information can be distinguished from other types of genetic and non-genetic information and also synthesises the determinative significance of genetic factors for the development of human behavioural traits. Undertaking this analysis enables the ethical issues raised by this research to be debated in an appropriate context and indicates that separate policy considerations are warranted.

     

清代中期“以礼代理”说刍议

清代中期,以凌廷堪、焦循、阮元为代表的汉学家提出了“以礼代理”说,即主张用礼学代替理学。他们认为,儒学的中心是“礼”而不是“理”,脱离了“礼”而言“理”,只能导致师心自用以及对人的具体情感的漠视。这一学说是清初顾炎武所倡导的学术方向的继续,它把人们的目光由内在精神变革转向对外在制度的关注;同时,这一学说明确反对以抽象化的“理”来约束人们的行为,它在一定程度上减轻了理学所带来的消极影响。     

Young children's sensitivity to probabilistic phonotactics in the developing lexicon

A series of three experiments examined children's sensitivity to probabilistic phonotactic structure as reflected in the relative frequencies with which speech sounds occur and co-occur in American English. Children, ages 212 and 312 years, participated in a nonword repetition task that examined their sensitivity to the frequency of individual phonetic segments and to the frequency of combinations of segments. After partialling out ease of articulation and lexical variables, both groups of children repeated higher phonotactic frequency nonwords more accurately than they did low phonotactic frequency nonwords, suggesting sensitivity to phoneme frequency. In addition, sensitivity to individual phonetic segments increased with age. Finally, older children, but not younger children, were sensitive to the frequency of larger (diphone) units. These results suggest not only that young children are sensitive to fine-grained acoustic-phonetic information in the developing lexicon but also that sensitivity to all aspects of the sound structure increases over development. Implications for the acoustic nature of both developing and mature lexical representations are discussed.     

Resisting body dissatisfaction: fat women who endorse fat acceptance

Fat women who endorsed fat acceptance (N=128) were recruited from Radiance Magazine. Relationships between objectified body consciousness (OBC), body esteem, and psychological well-being for the mostly European American sample were similar to those found in other samples. OBC was independently related to body esteem when weight dissatisfaction was controlled. Those who endorsed the need for social change in attitudes towards fat people had higher body esteem and self-acceptance, and lower body shame, than those who endorsed personal acceptance of body size only.     

评发生认识论的"反省抽象"范畴

论文分析了皮亚杰发生认识论中“反省抽象”范畴的发展脉络、主要内涵及其与某些相关概念(如概括化、平衡化、矛盾与否定的构造、意识化与觉知等)的联系。作者认为：反省抽象不仅体现皮亚杰的独创性．而且也是发生认识沦中最为核心和最为重要的概念。它合理地解释了知识创新的源泉,使发生认识论的逻辑一数学范畴研究及认知发展一般规律的研究奠基于科学认识论之上。作者主张应准确继承皮亚杰的学术遗产,深化对认知发展机制的探索。     

Comorbidity between and within childhood externalizing and internalizing disorders: reflections and directions

The term and concept of lcomorbidity has been mired in controversy, although there is little question that the existence of covariation among psychiatric diagnoses poses significant challenges to current models of psychiatric classification and diagnosis. The papers in this Special Section underscore a number of important issues relevant to the comorbidity between and within childhood externalizing and internalizing disorders, and illustrate both methodological and substantive reasons for such comorbidity. Weiss, Susser, and Catron's distinction among common, broad-band specific, and narrow-band specific features provides a helpful framework for understanding the comorbidity of childhood externalizing and internalizing disorders (B, Weiss, K. Susser, & T. Catron, 1998). Hierarchical models of psychopathology help to dissolve the distinction between splitters and lumpers and point to variables that may elucidate the etiology of externalizing and internalizing disorders.     

Tribal Participatory Research: Mechanisms of a Collaborative Model

Although much social science research has been conducted within American Indian and Alaska Native (AIAN) communities, relatively little research has been conducted by or for those communities. We describe an approach that facilitates the active involvement of AIAN communities in the research process, from conceptualizing the issues to be investigated to developing a research design, and from collecting, analyzing, and interpreting the data to disseminating the results. The Tribal Participatory Research (TPR) approach is consistent with recent developments in psychology that emphasize the inclusion of community members and the social construction of knowledge. We describe the foundations of the approach and present specific mechanisms that can be employed in collaborations between researchers and AIAN communities. We conclude with a discussion of the implications of the use of TPR regarding project timelines and budgets, interpretation of the data, and ultimately the relationships between tribes and researchers.     

Genetic and Environmental Influences on Psychopathy Trait Dimensions in a Community Sample of Male Twins

Psychopathy appears to be comprised of two broad dimensions: impulsivity/antisocial behavior and interpersonal detachment/callousness. This study examined the extent to which variance in these 2 psychopathy trait dimensions was associated with common or unique genetic, shared, and nonshared environmental factors in two independent samples of reared together 16–18-year-old male twins. One sample included 142 monozygotic (MZ) and 70 dizygotic (DZ) pairs; the other sample included 128 MZ and 58 DZ pairs. Boys completed the Minnesota Temperament Inventory (MTI), a 19-item measure that contains separate subscales: Antisocial and Detachment. Variance in the Antisocial and Detachment scales was associated with additive genetic factors and neither scale was associated with shared environmental factors. As expected, the bivariate biometric analysis suggested genetic influence on the covariance of the scales. The results are consistent with theoretical models of psychopathy that posit some independence in the etiology of the two major trait dimensions of psychopathy.     

《圣迹图》版本初探

多年来 ,研究孔子的专书中涉及《圣迹图》版本研究的几乎没有 ,且为之介绍的专文也难得一见。《圣迹图》有绘本、石刻本、木刻本三种类型 ,乃为画家及刻梓者出自以垂永久之思 ,以求望图而知所考据 ,入室如见其人之感受。从中国版画史的角度来看 ,《圣迹图》中孔子形象 ,为后人运用想像力 ,揣摩当时的情景 ,选取孔子生平事迹中最为人所津津乐道的难忘情节创造出来的。本文就传世的各种版本及内容作一些考证及探讨。