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Abnormal arousal processes, sympathetic influences, as well as wake-like alpha activity during sleep were reported as pathophysiological features of Nightmare Disorder. We hypothesized that in Nightmare Disorder, wake-like cortical activity and peripheral measures linked to arousals would be triggered by physiological processes related to the initiation of REM periods. Therefore, we examined electroencephalographic (EEG), motor and autonomous (cardiac) activity in a group of nightmare (NM) and healthy control (CTL) subjects during sleep-state-transitions while controlling for the confounding effects of trait anxiety. Based on the second-nights’ polysomnographic recordings of 19 Nightmare Disordered (NM) and 21 control (CTL) subjects, we examined the absolute power spectra focusing on the alpha range, measures of heart rate variability (HRV) and motor (muscle tone) activity during pre-REM and post-REM periods, separately. According to our results, the NM group exhibited increased alpha power during pre-REM, but not in post-REM, or stable, non-transitory periods. While CTL subjects showed increased HRV during pre-REM periods in contrast to post-REM ones, NM subjects did not exhibit such sleep state-specific differences in HRV, but showed more stable values across the examined sleep stages and less overall variability reflecting generally attenuated parasympathetic activity during sleep-state-transitions and during stable, non-transitory NREM states. These differences were not mediated by waking levels of trait anxiety. Moreover, in both groups, significant differences emerged regarding cortical and motor (muscle tone) activity between pre-REM and post-REM conditions, reflecting the heterogeneity of NREM sleep. Our findings indicate that NM subjects’ sleep is compromised during NREM–REM transitions, but relatively stabilized after REM periods. The coexistence of sleep-like and wake-like cortical activity in NM subjects seems to be triggered by REM/WAKE promoting neural activity. We propose that increased arousal-related phenomena in NREM–REM transitions might reflect altered emotional processing in NM subjects. 相似文献
603.
Aya H. Kimura 《Science as culture》2019,28(3):327-350
ABSTRACTAfter the Fukushima nuclear accident, many laywomen established citizen radiation measuring organizations (CRMOs) to measure the concentration of radioactive materials in food to ensure its safety. These women had diverse motivations. As caretakers, many wanted to protect their families. Others saw it as important to arm themselves with science when the broader social discourse portrayed contamination concerns as irrational and harmful to food producers, and stereotyped women as overreacting due to their scientific illiteracy. Some women also became empowered and productive citizen scientists, influenced by the popular idea of women-in-science. The fluid relationships between scientization and citizens’ collective mobilizations make it particularly illuminating to analyze such shifting relationships between activism and science using Gieryn’s concept of boundary-work. Women’s motivations to participate in CRMOs were closely connected to the expanding scientization—the increasing role of science in defining and prescribing social problems. While they shared many sentiments with anti-nuclear movements, women often performed boundary-work in a way that constructed science as irreconcilable with activism. Many saw activism as threatening the legitimation provided by science: a particularly important issue for women, who were stereotyped and policed as anti-science and irrational after the accident. Activism was also understood as a highly masculinized space incompatible with the feminized caretaker role that many women took on, which initially provided the rationale for their involvement in citizen science. The concept of gendered scientization highlights how the turn to science in dealing with environmental threats might result in gendered opportunities and challenges in collective mobilization by citizens. 相似文献
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Luigi Coccioli 《World Futures: Journal of General Evolution》2013,69(1-2):101-109
The author describes several origins of current international financial problems. Shortcomings of current solutions are analyzed, and solutions which the author thinks are more appropriate are presented. 相似文献
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