Global Justice for Humans or for all Living beings and what Difference it Makes

I begin with an account of what is deserved in human ethics, an ethics that assumes without argument that only humans, or rational agents, count morally. I then take up the question of whether nonhuman living beings are also deserving and answer it in the affirmative. Having established that all individual living beings, as well as ecosystems, are deserving, I go on to establish what it is that they deserve and then compare the requirements of global justice when only humans are taken into account with the requirements of global justice when all living beings are taken into account.     

《史记》对汉初人口状况的记载分析

《史记·高祖功臣侯者年表》序中的“汉兴……户口可得而数者十二三”这句话,是关于汉初人口状况的最早记载。对这句话的不同理解,影响到人们对汉初人口数量及其他相关历史问题的看法。学界对于这句话有着多种理解。本文认为司马迁此语,应当仅是针对汉初朝廷直接控制区内的户口而言,当时占去最富庶的东、南半壁江山的诸侯王国,是被排除在外的。     

人类行为遗传学的伦理问题

行为遗传学是试图定位与行为特性有关的特殊基因或基因组及了解基因与环境之间复杂关系的一种研究.行为遗传学是研究正常范围内的非病理变化,与人类疾病遗传学存在差异.行为遗传学研究面临许多伦理学问题,诸如,智力的遗传性,基因能否决定一切,生物社会学与人类文化评估,生命伦理学与行为遗传学的关系等,因此,对行为遗传学研究结果的阐述必须十分谨慎.     

A Friend in Creed: Does the Religious Composition of Geographic Areas Affect the Religious Composition of a Person's Close Friends?

Numerous theories of religion rest on the assumption that the religious composition of local populations influences the religious identities of a person's close friends, but there have been few empirical tests of this assumption. Using a combination of data on the religious identity of close friends (from the 1988 and 1998 General Social Survey) and information on the religious composition of counties (from the U.S. Religious Congregations and Membership Study) we find that despite tendencies toward religious homogeneity, the religious composition of the surrounding population has an effect on the proportion of a respondent’s same‐religion friends and on the proportion of friends belonging to specific other religious groups. Local population characteristics are unrelated to the proportion of respondents’ friends known in congregational settings. Results have implications for a broad range of sociological theories of religion as well as research examining the impact of same‐congregation and same‐religion friends (e.g., health and well‐being).     

基因多态性对情绪调节神经回路的影响

随着脑成像和基因分析等新技术手段的综合运用, 情绪调节的神经生物学基础研究有了很大进展。综述相关研究表明: 情绪调节的神经回路涉及背侧-腹侧前额叶、前额叶-杏仁核和皮层-边缘系统的相互作用, 这些神经回路受到5-羟色胺传运体(5-hydroxytryptamine transporter, 5-HTT)、儿茶酚转甲酶 (Catechol-O-methyltransferase, COMT)和色氨酸羟化酶2(Tryptophan hydroxylase 2, TPH2)等基因变异, 以及不同基因多态之间交互作用的影响。情绪调节神经回路的功能出现障碍将导致情绪疾病的产生。     

反社会行为潜在遗传因素的全基因组关联分析

反社会行为是一种受基因和环境共同影响的复杂性行为, 但单个基因如单胺氧化酶基因(MAOA)、5-羟色胺转运体启动因子基因(5-HTT)、儿茶酚-o-甲基转移酶(COMT)基因的影响并不能全面解释其产生的分子遗传机制。来自分子遗传学研究取向的方法—— 全基因组关联分析(genome-wide association study, GWAS), 把人类基因组中数以百万计的单核苷酸(SNPs)和复制数变异(CNVs)作为遗传标记, 在全基因组层面上, 开展多中心、大样本的关联研究, 经过反复验证来发现与外在表型相关的基因位点, 为进一步了解反社会行为复杂分子遗传机制提供了重要的线索。未来的研究应该通过科学的实验设计将精确的基因分型技术与心理、环境因素相结合, 实现对复杂性行为或特质的基因-心理-环境模型的成因性分析。     

非药物成瘾的遗传学和神经生物学机制研究述评

非药物成瘾又称“非物质相关性成瘾”或“行为成瘾”。特征性表现包括对成瘾对象的渴望、受损的冲动控制、对成瘾对象的耐受、撤退反应和高复发率等。目前发现的非药物成瘾类型包括病理性赌博、网络成瘾、购物成瘾、游戏成瘾、性瘾以及贪食等。非药物成瘾与药物成瘾在症状学上表现出很高的相似性且具有较高的共病率, 提示二者之间可能存在着共同的发病机制。从遗传学和神经生物学的角度探讨非药物成瘾的机制具有重要的理论价值和临床应用价值。家庭研究和双生子研究发现, 男性的病理性赌博和贪食障碍具有中度以上的遗传度。分子遗传学研究发现, 单胺能神经递质相关基因, 如5-羟色胺转运体基因、多巴胺受体基因和单胺氧化酶A基因等, 与非药物成瘾有关。神经影像学研究发现, 非药物成瘾者脑内负责奖赏,线索加工和冲动控制的神经通路活动性异于正常对照。未来研究需要进一步从多个角度入手, 探讨非药物成瘾与药物成瘾的共性和特性。     

老年刻板印象威胁及其研究操纵

随着人口老龄化的不断加剧, 老年刻板印象威胁受到越来越多的关注。不同于种族或民族、性别等刻板印象威胁, 老年刻板印象威胁表现出累积性、共通性与连续性等特征。目前关于老年刻板印象威胁的研究多集中于认知老化尤其是记忆老化上, 关注老年刻板印象威胁对老年司机和老年员工的消极影响。消除与降低老年刻板印象威胁的消极效应可以从认知改变、群体认同、代际接触、老龄自我实现和个性化以及媒体宣传等五个方面来进行。在实验室研究中, 老年刻板印象威胁有外显与内隐两种不同的操纵形式。未来可以从扩展研究领域、细化“年龄”差异、比较整体效应大小和性别差异、侧重积极效应以及加强本土化检验和跨文化比较研究等方面来深化。     

一个参与者眼中的行为遗传学史上的里程碑

行为遗传学的历史,从横切面看,就好似一个由心理学、遗传学、生物学、进化论、人类学、人口学、生物统计、社会学以及法哲学等学科组合成的万花筒。任何一对学科的演进都呈正相关。虽然任何一对学科都不至于相互否定,但是,他们各自独特的历史和人物,又使得每一对学科并不完全相似     

A Population-Based Twin Study of Parentally Reported Tactile and Auditory Defensiveness in Young Children

  Some adults and children exhibit defensive behaviors to tactile or auditory stimulation. These symptoms occur not only in subsets of children with ADHD, autism, and Fragile X syndrome, but also in the apparent absence of accompanying disorders. Relatively little research explores the correlates and antecedents of sensory defensiveness. Using a population-based sample of 1,394 toddler-aged twins, mothers reported on tactile and auditory defensiveness, temperament, and behavior problems. The incidence of defensive symptoms was widely distributed, with some accumulation of cases in the extreme range. Girls were overrepresented in the extreme tactile defensiveness group. Both auditory and tactile defensiveness were modestly associated with fearful temperament and anxiety, but they were relatively distinct from other common dimensions of childhood behavioral dysfunction. Twin correlations for the full range of scores and concordance rates for the extremes suggested moderate genetic influences, with some indication that the tactile domain might be more heritable than the auditory domain.