Scaling Up the Self,Scaling Down the World: Self-objectification and the Politics of Carbon Offsets and Personalised Genomics

Two global initiatives, the Genographic Project and the Carbon Lottery, share an ambition to make abstract, global processes—human evolution and climate change—comprehensible and engaging to non-specialists. Despite their differences, they both do so by means of self-objectifications that scale up the selves of participants and scale down complex, spatio-temporal models of human–world relations. The author’s auto-ethnographic experiences in both initiatives illustrate how carbon calculators and personalised genomics involve a pragmatics of scale that evaluates and compares users on the basis of their relative expression of, or deviation from, a standard. Furthermore, this is not based on actual resources that participants do or do not possess, but on forms of capitalist exchange that underwrite carbon trading and population genomics, as experts and corporations make intellectual property derived from purportedly rare DNA and sustainable practices, which are typically indigenous and non-western. In fact, the global inequalities that make possible transactions in carbon offsets and genetic ancestry are obscured from view. As a result, though initiatives like the Genographic Project and Carbon Lottery may provide comprehensible self-objectifications, they potentially make the world more unequal in the process.     

Response inhibition and interference control: Effects of schizophrenia,genetic risk,and schizotypy

The ability to inhibit inappropriate responses and suppress irrelevant information is a core feature of executive control. In this study, we provide a detailed analysis of prepotent response inhibition and interference in patients with schizophrenia. To further test the role of genetic factors and subclinical schizophrenia‐like traits, we additionally studied clinically unaffected, first‐degree relatives of schizophrenia patients and assessed dimensions of schizotypy in both relatives and healthy controls. Inhibition and interference control were assessed using a battery comprising the antisaccade, Stroop, stop signal, go/no‐go, flanker, and Simon tasks. Schizophrenia patients differed from both relatives and controls in making more errors on the antisaccade task and having longer response times on the Stroop task, especially the incongruent condition. Patients also had general, that is, condition independent, increases in reaction times on the go/no‐go and flanker tasks and made more errors on the flanker and Simon tasks, suggesting general performance impairments independent of inhibitory demand. Relatives were characterized by hypometric antisaccade amplitude gain despite normal prosaccades, suggesting a selective deficit in non‐standard sensorimotor transformations. Schizotypy was correlated with inhibitory performance across a number of tasks in both relatives and controls. Generally, these effects were independent of verbal intelligence levels. Overall, the findings point to rather selective impairments of inhibitory control in the schizophrenia spectrum and confirm a previously observed deficit in antisaccade spatial accuracy as an endophenotype of schizophrenia.     

The Ethical Implications of Using Genetic Information in Personnel Selection

Biology, during the last decade in particular, is making substantial headway into our social theories of business and behavior. While the social sciences rush to keep up with the advancement of knowledge, we highlight the need for an ethics discussion to also keep pace. Although the implications to theory are important, our focus is on how new knowledge has the capacity to alter the formulation and practice of business policy, which we believe is potentially profound. Furthermore, the ethicality of a set of issues can depend heavily on one’s perspective, and differing views may not always be compatible. With this in mind, we discuss the ways in which one area of emerging biological knowledge—behavioral genetics—invites a rethinking of the nuances of four long-standing topic areas of business ethics surrounding personnel selection; and we do so from two perspectives—that of the employer and of the job seeker. The four ethical topics are (a) the static (mostly) nature of genetic information that is out of an individual’s control, (b) faking and lying during selection processes, (c) privacy, and (d) stigmatization of minority groups.     

Does Lack of “Genetic-Relative Family Health History” Represent a Potentially Avoidable Health Disparity for Adoptees?

Many adoptees face a number of challenges relating to separation from biological parents during the adoption process, including issues concerning identity, intimacy, attachment, and trust, as well as (for older adopted children) language and other cultural challenges. One common health challenge faced by adoptees involves lack of access to genetic-relative family health history (GRFHx). Lack of GRFHx represents a disadvantage due to a reduced capacity to identify diseases and recommend appropriate screening for conditions for which the adopted person may be at increased risk. In this article, we draw out common features of traditionally understood “health disparities” in order to identify analogous features in the context of adoptees’ lack of GRFHx.     

Role of female behavior in controlling population growth in mice

Sex ratio does not appear to be a factor in generating the characteristic population growth curve. Freely growing populations of house mice, consisting of all females and one male, stopped their growth at approximately the same densities as normal sexratio populations used as references. The mechanism(s) of female control of population dynamics may be related to female aggressive behavior. As the all-female/one-male populations approached their maximum size, the females began to show wounding patterns and social hierarchies in much the same manner as males in populations with normal sex ratios. The male in each of the populations was severely wounded in the posterior region, and each lost its tail as a result of injuries which could have been inflicted only by the females. The female social hierarchy can be seen only when there has been reproduction and population growth. Assembled populations of all females rarely exhibit aggressive behavior. Female aggression becomes apparent only when the population approaches its maximum size and thereafter. These data are consistent with the hypothesis that males are competitive among themselves for territory and social rank, and ultimately to mate with the females. Other investigators have indicated that females respond to population size, which may reflect increased competition between the females with the establishment of territories. Thus female agression may control population growth, a role previously ascribed to male aggression.     

基于脑结构像的精神分裂症机器学习分类

将机器学习应用于精神疾患的临床和基础研究是近年来的趋势。研究者将机器学习应用于精神分裂症患者及高危人群的T1加权像和弥散张量成像的脑影像数据中, 为了解疾病的生理病理学机制提供帮助。回顾以往研究发现额叶及颞叶的脑结构特征具有较高的区分能力, 行为数据和脑影像数据结合的分类效果优于单模态数据。现阶段研究存在样本量不足和泛化能力欠缺的局限, 未来研究应注意扩大样本量、制定标准化的分类方法, 从而进一步探究机器学习在精神疾患中的作用。     

Minority Group Membership and Perceptions of Self-help: Evidence from Israel

This study explores the meanings associated with the term ‘self-help’ in the general Arab population in Israel. It compares these associated meanings across various groups created by several demographic variables. The Arab population in Israel numbers nearly one million, comprising 18% of the total population of the state. The study used a random sample of 250 participants, representative of the general Arab population in Israel. Data was collected in a telephone survey which lasted 3–7 minutes. Three themes surfaced as the most prevalent meanings associated with the concept ‘self-help’: the individual meaning, which refers to one's ability to solve one's own problems and to rely on one's own strengths and resources; helping the ‘other’; and helping the needy. Significant differences in the associated meanings of the self-help concept related to level of education, marital status, and whether the respondent had heard of the self-help concept. The significance of the findings is discussed within several frames of reference. First, they are examined within the context of a particular minority culture which is constantly interacting with Israeli Jewish cultural values and is undergoing a change from traditional systems of values to modern Western ones. Second, the universal and particular attributes of the self-help phenomenon are outlined. Third, the initial developmental stages of self-help organizations within the Arab population living in Israel are discussed.     

Three Laws of Behavior Genetics and What They Mean

Behavior genetics has demonstrated that genetic variance is an important component of variation for all behavioral outcomes, but variation among families is not. These results have led some critics of behavior genetics to conclude that heritability is so ubiquitous as to have few consequences for scientific understanding of development, while some behavior genetic partisans have concluded that family environment is not an important cause of developmental outcomes. Both views are incorrect. Genotype is in fact a more systematic source of variability than environment, but for reasons that are methodological rather than substantive. Development is fundamentally nonlinear, interactive, and difficult to control experimentally. Twin studies offer a useful methodological shortcut, but do not show that genes are more fundamental than environments.     

皮亚杰的方法论：体系、优势与启示

皮亚杰的方法论体系包括：(1）发生学的理念;(2)“适应”和“运演”的理论解释工具;(3)获取资料的临床访谈法．他以这样的方法论体系而建立起来的理论具有：理性性、解释性、整体性等特征。皮亚杰方法论对我们当前的心理学研究具有启示意义。当前的一些研究在很大程度上,恪守着“实证”与“量化”的规范;却忽视研究主体的理性建构作用。     

人类基因组研究与遗传学的历史教训

第１８届国际遗传学大会达成的八点共识对于人类基因组的研究及其应用具有重要意义,也指明了在遗传学及其应用问题上不同文化之间如何解决它们之间分歧的最佳途径。纳粹德国的优生实践和前苏联李森科学派的兴衰都给我们留下了不可忘记的教训。围绕中国母婴保健法的争论反映了科学、伦理和政策的交叉。我们的基因组研究和遗传服务是为了增进个人的健康和促进家庭的幸福,而不能也不应以减少残疾人口为目标。在基因组研究和遗传服务中