有关智力的遗传研究演进

智力是被行为遗传学广泛研究的重要内容之一。过去十几年问。有关智力的遗传研究超越了最基本的先天与后天之争,通过发展的遗传分析、多变量遗传分析以及对遗传与环境交互作用的探讨获得了许多重要发现。分子遗传学的发展更是为智力研究展开了新的一页,使得确定与特定认知能力有关的基因成为可能。     

Assessing mobility in an aging society: Personal and built environment factors associated with older people’s subjective transportation deficiency in the US

This study analyzed subjective transportation deficiency, in terms of missing activities due to lack of transportation, of the older population aged 65 and over in the United States. This study found that those who have lower personal automobile accessibility and minority females are more likely to experience transportation deficiency. Older people who have lower income, have lived for a relatively short period (3–10 years) in their communities, and live with minors are also more likely to experience lack of transportation. Older people who live in suburban communities have greater transportation deficiency, but the placement of activity locations within walking distance can improve transportation deficiency among older people who do not drive. The availability of public transit services within walking distance and knowledge about transportation alternatives do not significantly affect the transportation deficiency of the older population. The results indicate that a substantive focus should be given to how to help the older population keep driving as long as they can, and aid communities with high concentrations of older minority females. Also, developing activity clusters containing commercial and social service facilities in suburban areas with high concentrations of older populations, has the potential to alleviate transportation deficiency among this widely observed group of people who age in place.     

EXPLORING THE CONCEPT OF SPIRIT AS A MODEL FOR THE GOD-WORLD RELATIONSHIP IN THE AGE OF GENETICS

Abstract. The cultural impact of genetics focuses the intellectual and moral challenge of science to theology. Many traditional images of God and the God-world relation are inadequate to represent religious ideas in a world whose self-understanding has been transformed by genetics. Such images also lack the power to help in approaching the ethical challenges of this new era. The way conceptions of the God-world relation can be modified in the light of genetic knowledge is explored by examining how far a new conception of Spirit can function alongside contemporary genetic views of human life in nature. The relationship between genetic theories of human behavior and evolution is related to the revised conception of Spirit.     

一般人格因素：虚妄的杜撰还是真实的存在

一般人格因素(General Factor of Personality, GFP)是人格层次结构中处于最高阶的单一因素。该因素被认为是最一般的非认知人格因素,且一般人格因素分数高的人在进化中具有更好的适应性。自2007年Musek 提出该概念之后,一般人格因素研究已成为人格研究领域的重大热点问题。本文简要回顾了一般人格因素概念的历史源流,全面地介绍了一般人格因素的统计测量学证据、行为遗传学证据和一般人格因素与其它心理学变量的相关证据,并对现有的质疑与回应进行了概述。目前的研究表明从不同理论框架设计的人格问卷都能够提取一般人格因素,来自行为遗传学的多数证据支持一般人格因素的存在,一般人格因素被证明与社会适应性指标相关。最后,提出了一般人格因素未来研究的几点展望。     

Biosocial studies of antisocial and violent behavior in children and adults: a review

Despite increasing knowledge of social and biological risk factors for antisocial and violent behavior, we know surprisingly little about how these two sets of risk factors interact. This paper documents 39 empirical examples of biosocial interaction effects for antisocial behavior from the areas of genetics, psychophysiology, obstetrics, brain imaging, neuropsychology, neurology, hormones, neurotransmitters, and environmental toxins. Two main themes emerge. First, when biological and social factors are grouping variables and when antisocial behavior is the outcome, then the presence of both risk factors exponentially increases the rates of antisocial and violent behavior. Second, when social and antisocial variables are grouping variables and biological functioning is the outcome, then the social variable invariably moderates the antisocial–biology relationship such that these relationships are strongest in those from benign home backgrounds. It is argued that further biosocial research is critical for establishing a new generation of more successful intervention and prevention research.     

Genetic and environmental influences on individual differences in printed word recognition

The genetic and environmental etiologies of individual differences in printed word recognition and related skills were explored in 440 identical and fraternal twin pairs between 8 and 18 years of age. A theoretically driven measurement model identified five latent variables: IQ, phoneme awareness, word recognition, phonological decoding, and orthographic coding. Cholesky decomposition models on these five latent constructs revealed the existence of both common and independent genetic effects, as well as non-shared environmental influences. There was evidence for moderate genetic influences common between IQ, phoneme awareness, and word-reading skills, and for stronger IQ-independent genetic influences that were common between phoneme awareness and word-reading skills, particularly phonological decoding. Phonological and orthographic coding skills in word recognition had both significant common and significant independent genetic influences, with implications for "dual-route" and "connectionist" reading models, subtypes of reading disabilities, and the remediation of reading disabilities.     

Gene therapy: ethical issues

To discern the ethical issues involved incurrent gene therapy research, to explore theproblems inherent in possible future genetherapies, and to encourage debate within thescientific community about ethical questionsrelevant to both, we surveyed American Societyof Human Genetics scientists who engage inhuman genetics research. This study of theopinions of U.S. scientific experts about theethical issues discussed in the literature ongene therapy contributes systematic data on theattitudes of those working in the field as wellas elaborative comments. Our survey finds thatrespondents are highly supportive of thepotential use of somatic cell gene therapy tocure serious diseases in adults and children aswell as prospective offspring. A clearmajority, however, believe that using suchgenetic techniques for enhancement purposes isunacceptable. Delineating the line betweendisease/disorder and improvement/enhancementposes a problem not easily resolved and oneconducive to the growth of slippery-slopeapprehensions. The majority of respondents alsoadvocate germ-line therapy, in theory at least,and under similar restrictions, but theyrecognize the roadblock that the existence ofunanticipated negative consequences currentlypresents. Another complex matter involvestrying to determine appropriate reasons forchoosing target diseases for research, forwhich the dichotomy between rare single-geneand common multifactorial diseases reveals anongoing dilemma.     

Genetic Virtue Program: An Unfeasible Neo-Pelagian Theodicy?

In his article, “Genetic Engineering, Virtue-First Enhancement, and Neo-Irenaean Theodicy,” Mark Walker has ventured farther into science more than most when it comes to exploring theodicy. After exposing the Achilles heel of the traditional free-will defense, Walker develops the Irenaean and Augustinian responses to the anthropic problem. Most importantly for this discussion, Walker proceeds to propose Genetic-First-Enhancement as part of his neo-Irenaean theodicy formulation. Overall, there are two major concerns I raised: the impossibility of a gradient morality in the presence of free will, and the scientific impossibility of Genetic Virtue Program. However, my claims are falsifiable if future genetic modifications do indeed improve morality. Before that is proven, I agree with Walker that, yes, we should play God, albeit, with his proposed virtue-first program.     

EVOLUTION OF RELIGIOUS CAPACITY IN THE GENUS HOMO: ORIGINS AND BUILDING BLOCKS

The large, ancient ape population of the Miocene reached across Eurasia and down into Africa. From this genetically diverse group, the chimpanzees, bonobos, gorillas, and humans evolved from populations of successively reduced size. Using the findings of genomics, population genetics, cognitive science, neuroscience, and archaeology, the authors construct a theoretical framework of evolutionary innovations without which religious capacity could not have emerged as it did. They begin with primate sociality and strength from a basic ape model, and then explore how the human line came to be the most adaptive and flexible of all, while coming from populations with reduced genetic variability. Their analysis then delves into the importance of neurological plasticity and a lengthening developmental trajectory, and points to their following article and the last building block: the expansion of the parietal areas, which allowed visuospatial reckoning, and imagined spaces and beings essential to human theologies. Approximate times for the major cognitive building blocks of religious capacity are given.