Ordinal data,ordered scale points,and order statistics

This paper concerns ordinal responses. An ordered Dirichlet distribution describes prior and posterior beliefs about the cumulative probabilities of response categories. Associating the response categories with intervals of a latent random variable then induces a distribution on the order statistics of that variable. The psychometrician can use the asymptotic theory of order statistics to learn how distributional assumptions about the latent variable effect inference. An example relates the skewness of a latent variable to the proportional odds and proportional hazards models of McCullagh [1980].     

我国艾滋病流行的特点

我国艾滋病的流行有其自身的特点：１．人口多,多发病低,即使以目前的估计ＨＩＶ感染数３０万计,在世界上仍属极低水平;２．传播途径以吸毒为主,性传播为次,二者约为１０与１之比,这和世界各国正好相反;３．高危人群ＨＩＶ阳性率,指性病门诊者,妓女（暗娼）的阳性率都极低,约占０．０６％～０．０７％。目前我国还是以男性吸毒者为主要防治对象。     

The Concept of Abnormality in Medical Genetics

This paper explores usage of the concept ofabnormality in medical genetics and proposesdirectives for more careful usage of this concept.The conceptual difficulties are first explored, thena model is developed to assess actual usage, followedby analysis of a sample of genetic textbooks andgenetics literature. It appears that fact andvaluation are often intermingled, that referencestandards used to define 'genetic abnormalities' areoften not clear and that the concept of abnormality isoften used independent of the degree of certainty withwhich the altered genetype develops into a (seriously)harmful phenotype. On the basis of these findings itis argued that more restraint and more careful use ofthe concept of genetic abnormality of medical geneticsis appropriate as well as more agreement on the use ofreference standards.     

影响感觉寻求人格特质的生物遗传因素

综述了感觉寻求人格特质的生物遗传机制的相关研究。主要从3个方面对该问题进行了探讨：（1）单胺类物质与感觉寻求人格特质的关系;（2）激素对感觉寻求人格特质的影响;（3）感觉寻求人格特质的生物遗传性     

神经心理学手段及其在行为遗传学研究中的应用

神经心理学的检测手段包括神经心理学测验和仪器检查。行为遗传学是一门在多学科基础上发展形成的的交叉学科。近年来,应用神经心理学手段进行行为遗传学研究,已经取得了一些可喜的进展。     

Publics and Populations: The Politics of Ancestry and Exchange in Genome Science

While researchers collect and assemble relevant populations for genome studies, they are also, along with project designers and managers, interested in assembling publics. The public holds significant symbolic and discursive appeal for large-scale genome science. This is particularly the case in projects that collect or study aspects of human genome variation where histories of biological racism continue to cast a shadow over the promises of genomic medicine. In one of Canada's first large-scale biobanks, French Canadians, who are understood as a genetically close or homogenous population, are contrasted with what are referred to as ‘immigrants’ and ‘Québecers from various ethnic and racial backgrounds’ in public engagement and consultation forums. These latter groups, thought to provide a form of diversity, both in their views and their biology, are harnessed in the consultation practices as well as in the branding of the biobank. Within the local area of sample collection, the already constructed and available ways to categorise groups provide a powerful frame to narrate the relationship between the public and genome science. The process of making and consulting niche publics not only naturalises particular narratives of national belonging but also enables forms of exchange and sharing in international genome science. Just as assembling populations forms a central component of genome science, displays of publicness are integral for economies of exchange in genome science.     

Vulnerable Populations in Research: The Case of the Seriously Ill

This paper advances a new criterion of a vulnerable population in research. According to this criterion, there are consent-based and fairness-based reasons for calling a group vulnerable. The criterion is then applied to the case of people with serious illnesses. It is argued that people with serious illnesses meet this criterion for reasons related to consent. Seriously ill people have a susceptibility to “enticing offers” that hold out the prospect of removing or alleviating illness, and this susceptibility reduces their ability to safeguard their own interests. This explains the inclusion of people with serious illnesses in the Belmont Report’s list of populations needing special protections, and supports the claim that vulnerability is the rule, rather than the exception, in biomedical research.     

Commentary: What is the Meaning and Utility of the Psychopathy Concept?

The concept and measurement of psychopathy in young people is discussed with respect to five key issues: (1) the respective merits of self-reports and ratings by others; (2) whether callous/unemotional (CU) features may be more appropriately tapped by physiological measures; (3) the possible utility of genetic studies; (4) the distinctiveness of CU from other risk factors for antisocial behavior; and (5) the homogeneity of CU as a construct.