Hybrid route choice model incorporating latent cognitive effects of real-time travel information using physiological data

The proliferation of information systems is enabling drivers to receive en route real-time travel information, often from multiple sources, for making informed routing decisions. A robust understanding of route choice behavior under information provision can be leveraged by traffic operators to design information and its delivery systems for managing network-wide traffic. However, most existing route choice models lack the ability to consider the latent cognitive effects of information on drivers and their implications on route choice decisions. This paper presents a hybrid route choice modeling framework that incorporates the latent cognitive effects of real-time information and the effects of several explanatory variables that can be measured directly (i.e., route characteristics, information characteristics, driver attributes, and situational factors). The latent cognitive effects are estimated by analyzing drivers’ physiological data (i.e., brain electrical activity patterns) measured using an electroencephalogram (EEG). Data was collected for 95 participants in driving simulator experiments designed to elicit realistic route choices using a network-level setup featuring routes with different characteristics (in terms of travel time and driving environment complexity) and dynamic ambient traffic. Averaged EEG band powers in multiple brain regions were used to extract two latent cognitive variables that capture driver’s cognitive effort during and immediately after the information provision, and cognitive inattention before implementing the route choice decision. A Multiple Indicators Multiple Causes model was used to test the effects of several explanatory factors on the latent cognitive variables, and their combined impacts on route choice decisions. The study results highlight the significant effects of driver attributes and information characteristics on latent cognitive effort and of route characteristics on latent cognitive inattention. They also indicate that drivers who are more attentive and exert more cognitive effort are more likely to switch from their current route by complying with the information provided. The study insights can aid traffic operators and information service providers to incorporate human factors and cognitive aspects while devising strategies for designing and disseminating real-time travel information to influence drivers’ route choices.     

Views of a good life and allostatic load: Physiological correlates of theories of a good life depend on the socioeconomic context

This research examines the relationship between one’s theory of a good life and allostatic load, a marker of cumulative biological risk, and how this relationship differs by socioeconomic status. Among adults with a bachelor’s degree or higher, those who saw individual characteristics (e.g. personal happiness, effort) as part of a good life had lower levels of allostatic load than those who did not. In contrast, among adults with less than a bachelor’s degree, those who saw supportive relationships as part of a good life had lower levels of allostatic load than those who did not. These findings extend past research on socioeconomic differences in the emphasis on individual or relational factors and suggest that one’s theory of a good life has health implications.     

The relations between neuroscience and human behavioral science.

Neuroscience seeks to understand how the human brain, perhaps the most complex electrochemical machine in the universe, works, in terms of molecules, membranes, cells and cell assemblies, development, plasticity, learning, memory, cognition, and behavior. The human behavioral sciences, in particular psychiatry and clinical psychology, deal with disorders of human behavior and mentation. The gap between neuroscience and the human behavioral sciences is still large. However, some major advances in neuroscience over the last two decades have diminished the span. This article reviews the major advances of neuroscience in six areas with relevance to the behavioral sciences: (a) evolution of the nervous system; (b) visualizing activity in the human brain; (c) plasticity of the cerebral cortex; (d) receptors, ion channels, and second/third messengers; (e) molecular genetic approaches; and (f) understanding integrative systems with networks and circadian clocks as examples.     

The psychobiology of stress

Stressful life experience can have significant effects on a variety of physiological systems, including the autonomic nervous system, the hypothalamic-pituitary-adrenal axis, and the immune system. These relationships can be bidirectional; for example, immune cell products can act on the brain, altering mood and cognition, potentially contributing to depression. Although acute physiological alterations may be adaptive in the short term, chronic or repeated provocation can result in damage to health. The central dogma in the field of stress research assumes a stereotyped physiological response to all stressors (the generality model). However, increasing evidence suggests that specific stressful conditions and the specific way an organism appraises these conditions can elicit qualitatively distinct emotional and physiological responses (the integrated specificity model). For example, appraisals of threat (vs. challenge), uncontrollability, and negative social evaluation have been shown to provoke specific psychobiological responses. Emotional responses appear to have specific neural substrates, which can result in differentiated alterations in peripheral physiological systems, so that it is incorrect to presume a uniform stress response.     

PIONEER IN BEHAVIORAL PHARMACOLOGY: A TRIBUTE TO JOSEPH V. BRADY

The contributions of Joseph V. Brady to behavioral pharmacology span more than 50 years and range from early studies using the Estes-Skinner (conditioned emotional response) procedure to examine drug effects and various physiological processes in experimental animals to the implementation of mobile methadone treatment services and to small group behavioral analyses in simulated space environments. This expansive range of activities is based on Brady's insight and innovative use of behavioral procedures, his spirited and unabashed enthusiasm for the discipline and its philosophical underpinnings, together with a collegiality and commitment to the experimental analysis of behavior that is both legendary and inspirational. These contributions are summarized and highlighted in this tribute that focuses primarily on Brady's contributions to behavioral pharmacology but which also acknowledges his conceptual and technical contributions spanning multiple disciplines.     

The Institute for Music Physiology and Musicians’ Medicine

The Institute of Music Physiology and Musicians' Medicine of the University of Music and Drama in Hannover, Germany, is a unique Institution in Europe whose scope includes teaching the basics of music physiology and musicians' medicine and research into the physiological and neurobiological principles of professional music performance and music perception. Furthermore, the institute conducts research into the causes of occupational injuries in musicians and provides means for prevention, diagnosis and treatment of such injuries.     

Reactive aggression in boys with disruptive behavior disorders: behavior,physiology, and affect

This study examined responses to peer provocation in boys ages 9–13 years who met symptomatic criteria for ADHD-only, ODD/CD-only, comorbid ADHD/ODD/CD, or no diagnosis. Boys participated in a reaction-time game that included standardized verbal and behavioral provocation. Their behavioral, physiological, and affective responses to this task were measured. Results showed that groups did not differ following high levels of provocation because all boys behaved aggressively. However, following low provocation boys with comorbid ADHD/ODD/CD had higher levels of behavioral aggression, had greater heart rate acceleration, and were rated as angrier than all other boys. In addition, boys with comorbid ADHD/ODD/CD held a grudge longer than other children. Results suggest that boys with comorbid ADHD/ODD/CD are especially reactive to provocation from their peers.     

Stress‐related exhaustion disorder – clinical manifestation of burnout? A review of assessment methods,sleep impairments,cognitive disturbances,and neuro‐biological and physiological changes in clinical burnout

The aim of this paper was to provide an overview of the literature on clinically significant burnout, focusing on its assessment, associations with sleep disturbances, cognitive impairments, as well as neurobiological and physiological correlates. Fifty‐nine English language articles and six book chapters were included. The results indicate that exhaustion disorder (ED), as described in the Swedish version of the International Classification of Diseases, seems to be the most valid clinical equivalent of burnout. The data supports the notion that sleep impairments are causative and maintaining factors for this condition. Patients with clinical burnout/ED suffer from cognitive impairments in the areas of memory and executive functioning. The studies on neuro‐biological mechanisms have reported functional uncoupling of networks relating the limbic system to the pre‐frontal cortex, and decreased volumes of structures within the basal ganglia. Although there is a growing body of literature on the physiological correlates of clinical burnout/ED, there is to date no biomarker for this condition. More studies on the role of sleep disturbances, cognitive impairments, and neurobiological and physiological correlates in clinical burnout/ED are warranted.     

Rudolph Hermann Lotze's philosophically informed psychology

This essay deals with four main topics: the notion of philosophical psychology; the idea that physical events and mental events cannot be compared to one another; psychophysical mechanism; and the theory of local signs. These are all key elements in the Medicinische Psychologie of Rudolph Hermann Lotze (1817‒1881). By philosophical psychology, Lotze understands not only the collection of experimental data regarding physiological and mental states but also their philosophical processing outlining an interpretation of the real nature of the mind‒body connection. Within this framework, Lotze introduces the psychophysical mechanism as based on a key philosophical idea: mind and body are incomparable, but, nevertheless, they are in reciprocal relation (Wechselwirkung). In virtue of said special relation, movements that take place in the mental sphere of reality are transferred or translated in the bodily sphere and vice versa. This rearrangement (Umgestaltung) from one sphere of reality to the other is termed by Lotze “transformation to equivalent.” Through the concept of equivalence, Lotze supports the idea that the mind and the body form an organic whole. However, psychophysical mechanisms should not be seen as not a fixed series of physical changes followed by an equally fixed series of mental changes: physical changes are “read,” organized, and then transformed by the mind into something purely mental. This, in turn, produces new mechanical force and more physical changes. Lotze's legacy and long-term impact is finally read against the background of his contributions.     

The Hearts and Guts of White People

Beginning with the experience of a white woman's stomach seizing up in fear of a black man, this essay examines some of the ethical and epistemological issues connected to white ignorance. In conversation with Charles Mills on the epistemology of ignorance, I argue that white ignorance primarily operates physiologically, not cognitively. Drawing critically from psychology, neurocardiology, and other medical sciences, I examine some of the biological effects of racism on white people's stomachs and hearts. I argue for a nonideal medical theory focused on improving wellness in a society that systematically has damaged the health of people of color. The essay concludes that to be fully successful, critical philosophy of race must examine not just the financial, legal, political, and other forms of racism, but also its biological and physiological operations.