Behavioral assessment of imipramine effects in a depressed child

A 7-year-old boy was diagnosed as suffering from childhood depression by two independent psychiatric evaluators who employed the Research Diagnostic Criteria. Multifaceted behavioral observations were performed on target behaviors which were identified as major problematic areas of functioning related to the child's depression. The behavioral assessment strategy included daily monitoring of on-task and disruptive behavior in the classroom, enuresis, and overall hygienic, social, and compliance behaviors as a means of identifying the specific drug-induced effects of an anti-depressant, imipramine. The assimilation and application of behavioral assessment strategies within child psychiatry have been slow and tenuous. Reasons for the resistance include theoretical differences and misconceptions among psychiatric personnel, who, although open to objective evaluations, may wish to employ nonbehavioral treatments such as pharmacologic agents. The primary purpose of this study was to demonstrate the viability of behavioral assessment as an integral adjunct to pharmacologic treatment in a psychiatric setting as a means of gauging the efficacy of a psychiatric intervention. Issues regarding the role of behavioral assessment in psychiatry and, in particular, pharmacologic interventions with depressed children are examined and discussed.This study was supported, in part, by NIMH Grant MH 30915.     

Self-control in pigeons under the Mischel paradigm

Walter Mischel studied self-control in preschool children in the following manner: if the child waited for an interval to end, he or she received the more preferred of two reinforcers; if the child responded to terminate the interval by ringing a bell, the less preferred reinforcer was given. We used an analogous procedure to study self-control in pigeons: if the bird waited for a trial to end, it received the more preferred reinforcer; if the bird terminated the trial by pecking a key, the less preferred reinforcer was given. We explored the effects on self-control of a number of variables analogous to those studied by Mischel and co-workers, e.g., presence versus absence of reinforcers, of alternative responses, and of stimuli during the wait interval; prior experience of the subjects; and test paradigm. The results obtained with pigeons paralleled the results obtained by Mischel with human children.     

Multivariate stochastic processes compatible with “aspect” models of similarity and choice

Various recent works have developed feature or aspect models of similarity and preference. These models are more concerned with the fine detail of the judgment process than were prior models, but nevertheless they have not in general developed an underlying stochastic process compatible with the assumed structure. In this paper, we show that a particular class of multivariate stochastic processes, namely those associated with the Marshall-Olkin multivariate exponential distribution, generates several of these models. In particular, such stochastic processes (appropriately interpreted) yield Tversky's elimination by aspects model, Edgell and Geisler's (normal) additive random aspects model, and Shepard and Arabie's additive cluster model.This work was supported by Natural Science and Engineering Research Council of Canada Grant A8124 to A.A.J. Marley.     

Preference for mixed versus constant delays of reinforcement: Effect of probability of the short, mixed delay

Preference for mixed versus constant delays of reinforcement was studied with a concurrent-chain procedure. Lever pressing by rats in concurrently available variable-interval 60-second initial links occasionally produced mutually exclusive terminal-link reinforcement delays. A constant delay of reinforcement (either 15 seconds or 30 seconds) composed one terminal link and mixed delays (.2 second and twice the value of the constant delay) were arranged in the other terminal link. The proportion of .2-second delays in the mixed-delay terminal link took on values of 0, .1, .25, .5, .75, .9, and 1.0 over experimental conditions. Based on relative rates of responding in the initial links, preference for the mixed delays was a negatively accelerated function of the proportion of short, mixed delays. Three of five rats preferred the mixed delays to the constant delays when the proportion of short, mixed delays was .1 or higher, and all five rats preferred the mixed delays when the proportion of short, mixed delays was .25 or higher. Neither Squires and Fantino's (1971) delay-reduction model of choice nor a model based on the harmonic mean reinforcement delay provided a close estimate of choice proportions over the range of short-delay proportions studied. The delay-reduction model underestimated choice for the mixed delays at low and intermediate proportions of short delays, and the harmonic-mean-delay model overestimated choice for the mixed delays at intermediate and high proportions of short delays.     

FUNCTIONAL ASSESSMENT,CURRICULAR REVISION,AND SEVERE BEHAVIOR PROBLEMS

An adolescent female with multiple handicaps and a long history of severely disruptive behavior participated in a functional assessment linked directly to specific revisions in her school curriculum. During Phase 1, reversal designs were used to test hypotheses pertaining to antecedent and auricular influences on problem behavior. During Phase 2, a multiple baseline across afternoon and morning time periods demonstrated that the auricular revisions were effective in eliminating severely disruptive behavior and increasing on-task responding. Data also showed that inappropriate “psychotic” speech was reduced and appropriate social interactions were increased. Follow-up results showed that the changes were maintained throughout the school year. Questionnaire data provided social validation of the procedures and outcomes. The findings are discussed in relation to their implications for functional assessment, individualized curricula, and positive programming for students with disabilities and serious behavior problems.     

A COMPREHENSIVE EVALUATION OF REINFORCER IDENTIFICATION PROCESSES FOR PERSONS WITH PROFOUND MULTIPLE HANDICAPS

We evaluated comprehensively a preference assessment for identifying reinforcers for persons with profound multiple handicaps. Four experiments were conducted involving 18 individuals. Results of Experiment 1 replicated previous findings in that the assessment identified student preferences for respective stimuli, and caregiver opinion of preferences did not coincide with the systematic assessment. Results of Experiment 2 indicated highly preferred stimuli were likely to function as reinforcers in training programs, whereas stimuli not highly preferred did not function as reinforcers. Results of Experiment 3 suggested the 12 stimuli used in the assessment represented a comprehensive stimulus set for identifying preferences, although the utility of the set sometimes could be enhanced by caregiver opinion. Results of Experiment 4 indicated the assessment identified preferences likely to be maintained over time. Overall, results are discussed in terms of identifying limits and alternatives to a behavioral teaching technology when applied to persons with profound multiple handicaps.     

Choice as a function of local versus molar reinforcement contingencies.

Rats were trained on a discrete-trial probability learning task. In Experiment 1, the molar reinforcement probabilities for the two response alternatives were equal, and the local contingencies of reinforcement differentially reinforced a win-stay, lose-shift response pattern. The win-stay portion was learned substantially more easily and appeared from the outset of training, suggesting that its occurrence did not depend upon discrimination of the local contingencies but rather only upon simple strengthening effects of individual reinforcements. Control by both types of local contingencies decreased with increases in the intertrial interval, although some control remained with intertrial intervals as long as 30 s. In Experiment 2, the local contingencies always favored win-shift and lose-shift response patterns but were asymmetrical for the two responses, causing the molar reinforcement rates for the two responses to differ. Some learning of the alternation pattern occurred with short intertrial intervals, although win-stay behavior occurred for some subjects. The local reinforcement contingencies were discriminated poorly with longer intertrial intervals. In the absence of control by the local contingencies, choice proportion was determined by the molar contingencies, as indicated by high exponent values for the generalized matching law with long intertrial intervals, and lower values with short intertrial intervals. The results show that when molar contingencies of reinforcement and local contingencies are in opposition, both may have independent roles. Control by molar contingencies cannot generally be explained by local contingencies.     

Subjective probability and delay.

Human subjects indicated their preference between a hypothetical $1,000 reward available with various probabilities or delays and a certain reward of variable amount available immediately. The function relating the amount of the certain-immediate reward subjectively equivalent to the delayed $1,000 reward had the same general shape (hyperbolic) as the function found by Mazur (1987) to describe pigeons' delay discounting. The function relating the certain-immediate amount of money subjectively equivalent to the probabilistic $1,000 reward was also hyperbolic, provided that the stated probability was transformed to odds against winning. In a second experiment, when human subjects chose between a delayed $1,000 reward and a probabilistic $1,000 reward, delay was proportional to the same odds-against transformation of the probability to which it was subjectively equivalent.     

Choice, changeover, and travel: A quantitative model

Six pigeons were trained on concurrent variable-interval schedules in which responding on fixed-interval schedules was required to give access to the alternate schedule. Responding on the concurrent schedules was not allowed, after changing over had commenced, until the changeover schedule had been completed. In Parts 1 to 3 of the experiment, the changeover fixed-interval schedules were equal and were 0 s, 10 s, and 20 s, respectively. In each part, the relative frequency of reinforcement obtained on the concurrent schedules was varied over at least five conditions. In Part 4, the concurrent schedules were equal, and one changeover fixed-interval schedule was twice the other. Under these conditions, the absolute sizes of the changeover schedules were varied. Increasing the changeover requirement from 0 s to 10 s (Parts 1 and 2) resulted in increases in the sensitivity of behavior allocation to reinforcers obtained, but no further increase was obtained when the changeover schedules were increased to 20 s (Part 3). In Part 4, performance was biased towards the concurrent schedule that took less time to enter. These results are consistent with a subtractive punishment model of travel in which the degree of punishment is measured by the number of reinforcers apparently lost from a schedule when the subject changes to that schedule. Absolute times spent on the main keys could be accurately described by a previous model of changeover performance.     

A stochastic multidimensional scaling procedure for the empirical determination of convex indifference curves for preference/choice analysis

The vast majority of existing multidimensional scaling (MDS) procedures devised for the analysis of paired comparison preference/choice judgments are typically based on either scalar product (i.e., vector) or unfolding (i.e., ideal-point) models. Such methods tend to ignore many of the essential components of microeconomic theory including convex indifference curves, constrained utility maximization, demand functions, et cetera. This paper presents a new stochastic MDS procedure called MICROSCALE that attempts to operationalize many of these traditional microeconomic concepts. First, we briefly review several existing MDS models that operate on paired comparisons data, noting the particular nature of the utility functions implied by each class of models. These utility assumptions are then directly contrasted to those of microeconomic theory. The new maximum likelihood based procedure, MICROSCALE, is presented, as well as the technical details of the estimation procedure. The results of a Monte Carlo analysis investigating the performance of the algorithm as a number of model, data, and error factors are experimentally manipulated are provided. Finally, an illustration in consumer psychology concerning a convenience sample of thirty consumers providing paired comparisons judgments for some fourteen brands of over-the-counter analgesics is discussed.