Why do we move our eyes while trying to remember? The relationship between non-visual gaze patterns and memory

Non-visual gaze patterns (NVGPs) involve saccades and fixations that spontaneously occur in cognitive activities that are not ostensibly visual. While reasons for their appearance remain obscure, convergent empirical evidence suggests that NVGPs change according to processing requirements of tasks. We examined NVPGs in tasks with long-term memory (LTM) and working memory (WM) requirements. Experiment 1 yielded significantly higher eye movement rate (EMR) in tasks requiring LTM search than in a WM task requiring maintenance of information. Experiment 2 manipulated accessibility of items in study-test episodic tasks using the levels of processing paradigm. EMR was high in episodic recall irrespective of item accessibility. Experiment 3 examined functional significance of saccades in LTM tasks. Voluntary saccadic suppression produced no evidence that saccades contribute to task performance. We discuss the apparent epiphenomenal nature of spontaneous saccades from an evolutionary perspective and outline a neuroanatomical model of the link between the saccadic and memory system.     

鼻咽癌治疗方法的比较

鼻咽癌是我国南方省市最常见的头颈恶性肿瘤,放疗为其首选治疗方案,但患者五年生存率仍然不高。本文阅读国内外对鼻咽癌多种治疗方案的报道,结合湘雅医院、湘雅二医院对鼻咽癌某些治疗方案,通过分析对比不同治疗方案的疗效、患者生存质量及费用,讨论该病的最佳治疗方案,以期能在目前条件下提高鼻咽癌患者的治疗效果及生存质量。     

变长CD-CAT中的曝光控制与终止规则

本研究借鉴传统计算机化自适应测验的思想, 并结合认知诊断的特点, 在认知诊断框架下提出了4种变长CD-CAT的终止规则, 分别是属性标准误法(SEA)、邻近后验概率之差法(DAPP)、二等分法(HA)以及混合法(HM)。在未控制曝光和采用不同曝光控制条件下, 与HSU法及KL法进行了比较。研究结果表明：(1) 终止条件越严格, 平均测验长度越长, 按测验长度最大值终止的测验百分比越大, 模式判准率越高。(2) 当未加入曝光控制时, 4种新的终止规则均有较好表现, 与HSU法十分接近。随着最大后验概率预设值的增加或e的减小, 模式判准率呈上升趋势, 平均测验长度逐渐增加, 但在题库使用率方面均较差。(3) 当加入项目曝光控制时, 6种变长终止规则下的题库使用率有了极大的提升, 仍能保持较高的模式判准率, 并且不同的曝光控制方法对终止规则的影响是不同的。其中, 相对标准终止规则极易受到曝光控制方法的影响。(4) 综合来看, SEA、HM以及HA法在各项指标上的表现与HSU法基本一致, 其次为KL法和DAPP法。     

记忆搜索速度对短时记忆一生发展的影响研究

以横断研究方法探讨一生发展中搜索速度对短时记忆容量的影响。以记忆广度任务和斯腾伯格任务分别测量6~70岁被试短时记忆容量与记忆搜索速度。结果发现:记忆广度在16岁达到最高峰,以后开始下降;一生的不同阶段,斯腾伯格任务中成功搜索的加工过程基本一致,但搜索速度一直在发展;搜索速度可能是贯穿短时记忆发展一生的影响因素。     

Effects of nutritive and non-nutritive sucking on infant heart rate variability during the first 6 months of life

The effects of eating on heart rate variability (HRV) differ between adults and newborns. This may reflect the impact of suckling on the overall psychophysiological and autonomic nervous system maturation. The purpose of the present study was to explore whether the reactions of HRV during feeding change towards the adult pattern during the first 6 months of life. In addition, the effects of non-nutritive and nutritive sucking on heart rate (HR) and HRV were compared. The participants were 23 infants on whom recordings were performed as newborns and at 6, 12 and 24 weeks old. Nutritive sucking caused an increase in HR and a decline in HRV. The results were consistent with previous reports of a decrease in high frequency components of HRV during feeding in newborns, reflecting a decrease in parasympathetic activity. This response was apparent in all four ages studied, and remained similar throughout the 6-month period. However, age as an independent factor seemed to influence both HR and HRV. Pacifier sucking had no significant effects on HRV at any age. The results demonstrate the physical strain that sucking imposes on the baby, with a specific autonomic nervous system response involved. We consider this response an essential part of the overall psychophysiological maturation of infants.     

Frequency, determinants, and consequences of different drivers’ emotions: An on-the-road study using self-reports, (observed) behaviour, and physiology

In the present study, the frequency, determinants and consequences of three relevant emotions in traffic were investigated. Based on appraisal theory, it was predicted that the combination of three appraisal components (goal congruence, blame and threat) affects the occurrence of anger, anxiety and happiness. Participants (n = 44) filled in a questionnaire containing background and personality variables, and performed a test drive in an instrumented car. During the drive, speed and heart rate were registered and the traffic environment was recorded on video. Participants verbally reported scores for emotions and perceived risk. The most frequently occurring emotion was anxiety, followed by anger and happiness. Emotions while driving were related to emotional traits. Emotions while driving were also related to traffic events: anger and anxiety were both associated with goal incongruent events, and happiness with goal congruent events. Anger was mostly associated with other-blame and anxiety with situation-blame. Anger was mostly associated with events affecting impeded progress, and anxiety with events affecting safety. Anxiety, but not anger or happiness, was associated with increased perceived risk and with increased heart rate. Participants who reported anger drove faster and exceeded the speed limit more often on a 100 km/road section than participants who did not report anger. These and other results are discussed in terms of appraisal theory and state-trait differences in emotion.     

AGGRESSION AS POSITIVE REINFORCEMENT IN MICE UNDER VARIOUS RATIO‐ AND TIME‐BASED REINFORCEMENT SCHEDULES

There is evidence suggesting aggression may be a positive reinforcer in many species. However, only a few studies have examined the characteristics of aggression as a positive reinforcer in mice. Four types of reinforcement schedules were examined in the current experiment using male Swiss CFW albino mice in a resident—intruder model of aggression as a positive reinforcer. A nose poke response on an operant conditioning panel was reinforced under fixed‐ratio (FR 8), fixed‐interval (FI 5‐min), progressive ratio (PR 2), or differential reinforcement of low rate behavior reinforcement schedules (DRL 40‐s and DRL 80‐s). In the FR conditions, nose pokes were maintained by aggression and extinguished when the aggression contingency was removed. There were long postreinforcement pauses followed by bursts of responses with short interresponse times (IRTs). In the FI conditions, nose pokes were maintained by aggression, occurred more frequently as the interval elapsed, and extinguished when the contingency was removed. In the PR conditions, nose pokes were maintained by aggression, postreinforcement pauses increased as the ratio requirement increased, and responding was extinguished when the aggression contingency was removed. In the DRL conditions, the nose poke rate decreased, while the proportional distributions of IRTs and postreinforcement pauses shifted toward longer durations as the DRL interval increased. However, most responses occurred before the minimum IRT interval elapsed, suggesting weak temporal control of behavior. Overall, the findings suggest aggression can be a positive reinforcer for nose poke responses in mice on ratio‐ and time‐based reinforcement schedules.     

THE EFFECT OF CHANGES IN CRITERION VALUE ON DIFFERENTIAL REINFORCEMENT OF LOW RATE SCHEDULE PERFORMANCE

The differential reinforcement of low rate (DRL) schedule is commonly used to assess impulsivity, hyperactivity, and the cognitive effects of pharmacological treatments on performance. A DRL schedule requires subjects to wait a certain minimum amount of time between successive responses to receive reinforcement. The DRL criterion value, which specifies the minimum wait time between responses, is often shifted towards increasingly longer values over the course of training. However, the process invoked by shifting DRL values is poorly understood. Experiment 1 compared performance on a DRL 30‐s schedule versus a DRL 15‐s schedule that was later shifted to a DRL 30‐s schedule. Dependent measures assessing interresponse time (IRT) production and reward‐earning efficiency showed significant detrimental effects following a DRL schedule transition in comparison with the performance on a maintained DRL 30‐s schedule. Experiments 2a and 2b assessed the effects of small incremental changes vs. a sudden large shift in the DRL criterion on performance. The incremental changes produced little to no disruption in performance compared to a sudden large shift. The results indicate that the common practice of incrementing the DRL criterion over sessions may be an inefficient means of training stable DRL performance.     

When head is tempered by heart: Heart rate variability modulates perception of other-blame reducing anger

This study examined the relationship between heart rate variability (HRV), as an index of individual differences in emotion regulation, and perception of other-blame, as a mechanism of anger induction. The physiological responses were recorded while subjects read a story from a computer screen. The story narrated a negative event in self-referred way -dismissal from a job as the result of a colleague’s action- under conditions of intentionality versus non-intentionality. Cognitive and emotional variables were assessed by questionnaire immediately after the physiological test. The resulting structural model supports the conclusion that HRV exerts its regulatory influence directly on perception of other-blame rather than on emotion. In situations of intentionality, individuals with higher HRV make less extreme evaluation of the offender’s blame, versus those with lower HRV, thus leading to a reduction in anger reaction. These results suggest that HRV is a direct index of cognitive rather than emotional regulation.     

奖惩线索条件下内外倾个体的自主唤醒和行为反应

将停止信号任务和金钱激励延迟任务相结合,使用16导生理记录仪记录被试的生理指标,探讨内外倾者在动机凸显情景下的生理唤醒特点以及反应调节能力。结果发现,隐含奖励和惩罚线索呈现之后,内外倾者的心率增快,内倾者的皮肤电活动显著增强。在停止信号任务中的优势反应阶段,内外倾者表现为对奖励凸显线索刺激的反应时缩短;而在非优势反应阶段,和外倾者相比较,内倾者的抑制反应错误率增高。表明内外倾者在奖惩线索条件下表现出不同的生理唤醒特点和行为反应。