The Primary and Secondary Factors That Promote Destructive Personalities

The ability of behavioral scientists to assist society deal competently with destructive behavior relies upon a recognition of its causes. Despite the pervasiveness of violence in American society, the roots of destructiveness are still poorly understood. Five primary and five secondary factors found in the developmental histories of people who have become involved in serious destruction are identified and discussed. The confluence of these factors in the steps toward destructive acts are traced.     

Reasoning from transitive premises: An EEG study

Neuroimaging studies have contributed to a major advance in understanding the neural and cognitive mechanisms underpinning deductive reasoning. However, the dynamics of cognitive events associated with inference making have been largely neglected. Using electroencephalography, the present study aims at describing the rapid sequence of processes involved in performing transitive inference (A B; B C therefore “A C”; with AB meaning “A is to the left of B”). The results indicate that when the second premise can be integrated into the first one (e.g. A B; B C) its processing elicits a P3b component. In contrast, when the second premise cannot be integrated into the first premise (e.g. A B; D C), a P600-like components is elicited. These ERP components are discussed with respect to cognitive expectations.     

P300 as an index of attention to self-relevant stimuli

Past work suggests that information related to the self receives ‘preferential access’ to the limited pool of attentional resources. However, these studies have been limited by their reliance on response-time measures, which require overt responding and represent the combined effects of multiple stages of information processing. One aim of the present study was to extend past work by obtaining a response-independent index of attention allocation sensitive to changes in discrete stages of information processing. An additional goal was to explore the potential time course of differential sensitivity to self-relevant cues. We assessed the P300, an ERP component that provides an index of attentional resources, evoked by autobiographical self-relevant stimuli (e.g., one’s own name). As expected, P300 was augmented for self-relevant stimuli relative to control stimuli. In addition, analyses of P300 latency indicate that the effects of self-relevance are present during higher-order stages of cognitive processing related to selective attention. These results complement and extend previous work on the role of self-relevance in the selection of material for further processing.     

系统论视野下的心力衰竭与限钠利尿

综述心力衰竭时的神经、内分泌激活与血钠浓度的关系,血钠浓度在心力衰竭时的神经、内分泌的影响,并且运用系统论的观点重新认识心力衰竭与限钠利尿的关系,以便更好地处理这个治疗矛盾,打断心力衰竭发生发展的恶性循环,促使疾病向好的方向发展.同时,也为心力衰竭研究提出一种新思路和新的方法.     

ERP evidence of early cross-modal links between auditory selective attention and visuo-spatial memory

Previous dual-task research pairing complex visual tasks involving non-spatial cognitive processes during dichotic listening have shown effects on the late component (Ndl) of the negative difference selective attention waveform but no effects on the early (Nde) response suggesting that the Ndl, but not the Nde, is affected by non-spatial processing in a dual-task. Thus to further explore the nature of this dissociation and whether the Nd waveform is affected by spatial processing; fourteen adult participants performed auditory dichotic listening in conjunction with visuo-spatial memory in a cross-modal dual-task paradigm. The results showed that the visuo-spatial memory task decreased both the Nde and Ndl waveforms, and also attenuated P300 and increased its latency. This pattern of results suggests that: (1) the Nde reflects a memory trace that is shared with vision when the information is spatial in nature, and (2) P300 latency appears to be influenced by the discriminability of stimuli underlying the Nde and Ndl memory trace.     

Trait BIS predicts alpha asymmetry and P300 in a Go/No‐Go task

Inspired by the revised Behavioural Inhibition System (BIS) theory the present study probed the association between individual differences in Trait BIS and electroencephalogram indicators of conflict processing/inhibition. Sixty‐nine male participants either high or low in Trait BIS completed a Go/No‐Go task while the electroencephalogram was recorded. As expected, Trait BIS was associated with the No‐Go‐anteriorisation of the P300 event‐related potential (i.e. an index of response inhibition presumably generated in the dorsal anterior cingulate—an area implicated in conflict processing) and with No‐ Go‐related changes towards left frontal alpha activity (i.e. presumably more activity in right prefrontal cortex—an area implicated in response inhibition). These findings support the role of conflict processing attributed to BIS functioning in the revised theory. Copyright © 2009 John Wiley & Sons, Ltd.     

从社会认知神经科学角度谈自尊研究

文章从社会认知神经科学的角度对自尊研究的发展进行简要述评。影像学的证据表明,自尊与海马的体积相关;电生理学的证据表明,自尊与P300成分的激活有关。文章最后提出,对自尊神经机制的研究要尊重自尊概念的复杂性,同时要达到提高个体自尊水平的最终目的。     

结果的接近性对正性结果评价影响的电生理证据

结果的接近性是指对已发生事件的实际结果与在心理上的理想结果或期待结果之间差距的接近程度。实验采用事件相关电位技术和类老虎机赌博任务探讨了结果的接近性对正性结果评价的影响。(1)行为评定结果表明, 结果的接近性不同水平诱发了不同的情绪体验, “差一点输”的赢钱使被试更多感到庆幸, “最理想”的赢钱使被试感到高兴; 结果的接近性也影响了随后trial的反应时, 与“一般”的赢钱和“最理想”的赢钱相比, “差一点输的”赢钱后的下一个trial中被试的反应时明显变长。(2)脑电结果表明, 结果的接近性不同水平诱发了不同的FRN和P300, 与“一般”的赢钱和“最理想”的赢钱相比, “差一点输”的赢钱诱发了波幅更大的FRN和波幅更大潜伏期更长的P300。这说明结果的接近性明显地影响了正性结果的认知评价加工。     

P300和CNV在GKT的延时反应范式中测谎效果的分离

在杀人游戏情境中,设置无反馈和有反馈两个实验组,采用GKT（guilt knowledge test）的延时反应范式,考察P300和CNV两种ERP成分的测谎效果。结果发现：刺激呈现后大约450ms诱发了一个正性ERP成分（P300）,大约800ms诱发了一个负性ERP成分（CNV）。在有、无反馈两种实验范式下,P300和CNV两种测谎指标的变化情况发生了分离——有无反馈不影响P300峰值大小;而在有反馈条件下,“杀手”对于犯罪细节词语（探测刺激）的CNV明显增大。使用Bootstrap波幅差异分析法,分别计算P300和CNV在有、无反馈情况下的检出率,结果发现：两个指标的检出率在有、无反馈两种实验范式下的变化情况也发生了分离。这些结果表明：P300和CNV两个指标具有不同的测谎功能,这可能和它们所反映的不同欺骗心理过程有关。     

The clinical utility of the auditory P300 latency subcomponent event-related potential in preclinical diagnosis of patients with mild cognitive impairment and Alzheimer’s disease

The present meta-analysis investigated the clinical utility of the auditory P300 latency event-related potential in differentiating patients with Alzheimer’s disease (AD), patients with mild cognitive impairment (MCI), and unaffected controls. Effect size estimates were computed from mean P300 latency measurements at midline electrodes between patients and unaffected controls using the random effects restricted maximum likelihood model. The effects of clinical and ERP/EEG methological variables were assessed in a moderator analysis. P300 latency was found to be significantly prolonged in patients with AD (and MCI) compared to unaffected controls. Shortened P300 latencies were observed when comparing patients with MCI to patients with AD. Clinically relevant differences in P300 latency effect sizes were associated with mean age, interstimulus interval, stimulus difference, target frequency, reference electrode, and sampling rate. The meta-analytic findings provide robust statistical evidence for the use of the auditory P300 latency subcomponent as a biological marker of prodromal AD.