流式细胞术在骨髓增生异常综合征及再生障碍性贫血诊断中的应用

为探讨骨髓增生异常综合征患者与再生障碍性贫血患者骨髓髓系细胞的免疫表型变化,用流式细胞术检测骨髓增生异常综合征、再生障碍性贫血及正常对照髓系细胞的表面抗原。结果显示骨髓增生异常综合征组髓系细胞较正常对照组及再生障碍性贫血组表面抗原表达明显不同。因此,流式细胞术有助于二者的诊断及鉴别诊断。     

The Psychometric Properties of Dispositional Flow Scale-2 in Internet Gaming

This study examined the psychometric properties of the Dispositional Flow Scale-2 (DFS-2; Jackson and Eklund in Journal of Sports and Exercise Psychology, 24:133-150, 2002). One thousand five hundred and seventy-eight secondary school students (One thousand and seventy four males, four hundred and eleven females, ninety-three missing) from six schools in Singapore completed the questionnaires. Confirmatory factor analysis (CFA) was used to evaluate the factorial structure of the DFS-2. A nine-first-order factor model was compared to a higher order model with a global flow factor. Support was found for the higher order factor. Multigroup analysis demonstrated invariance of the factor forms, factor loadings, factor variances, and factor covariances across age and sex. The DFS-2 subscales were found to have acceptable reliability estimates, and convergent validity. We conclude that DFS-2 is a valid instrument for assessing global flow experience in Internet gaming.     

双侧前额皮层的语言功能--用近红外技术研究语言功能的初步实验

本文报告一个用近红外技术进行的语言认知脑成像实验.实验通过脑f血流的变化情况考察了双侧前额皮层对由不同通道输入的,不同语言的各个层次的认知反应.实验结果表明,双侧前额皮层对高层语义加工,包括对篇章的归纳与抽象,具有特殊的功能,这种功能的神经学分布是对称的,这种功能及其对称性不随语言和输入通道的变化而变化.相比之下,前额皮层对读、听语言材料以及听音乐却显得不敏感.局部血流的变化只显示其对上述任务的一般性的注意力控制.     

Cerebral blood flow differences between long-term meditators and non-meditators

We have studied a number of long-term meditators in previous studies. The purpose of this study was to determine if there are differences in baseline brain function of experienced meditators compared to non-meditators. All subjects were recruited as part of an ongoing study of different meditation practices. We evaluated 12 advanced meditators and 14 non-meditators with cerebral blood flow (CBF) SPECT imaging at rest. Images were analyzed with both region of interest and statistical parametric mapping. The CBF of long-term meditators was significantly higher (p < .05) compared to non-meditators in the prefrontal cortex, parietal cortex, thalamus, putamen, caudate, and midbrain. There was also a significant difference in the thalamic laterality with long-term meditators having greater asymmetry. The observed changes associated with long-term meditation appear in structures that underlie the attention network and also those that relate to emotion and autonomic function.     

临床外伤性视神经病变过度医疗的探讨

外伤性视神经病变是一类严重损害视功能的疾病,临床治疗上普遍存在着过度治疗的问题。原因是多样的,治疗标准不统一是主要原因。依据循证医学的成果,对临床外伤性视神经病变现阶段存在的过度医疗进行分析探讨,并提出了医者针对外伤性视神经病变过度医疗应采取的措施,获得最优化的诊疗方案。     

Advanced age brings a greater reliance on visual feedback to maintain balance during walking

We implemented a virtual reality system to quantify differences in the use of visual feedback to maintain balance during walking between healthy young (n = 12, mean age: 24 years) and healthy old (n = 11, 71 years) adults. Subjects walked on a treadmill while watching a speed-matched, virtual hallway with and without mediolateral visual perturbations. A motion capture system tracked center of mass (CoM) motion and foot kinematics. Spectral analysis, detrended fluctuation analysis, and local divergence exponents quantified old and young adults’ dynamic response to visual perturbations. Old and young adults walked normally with comparable CoM spectral characteristics, lateral step placement temporal persistence, and local divergence exponents. Perturbed visual flow induced significantly larger changes in mediolateral CoM motion in old vs. young adults. Moreover, visual perturbations disrupted the control of lateral step placement and compromised local dynamic stability more significantly in old than young adults. Advanced age induces a greater reliance on visual feedback to maintain balance during waking, an effect that may compensate for degradations in somatosensation. Our findings are relevant to the early diagnosis of sensory-induced balance impairments and also point to the potential use of virtual reality to evaluate sensory rehabilitation and balance training programs for old adults.     

The Conceptualization of Team Flow

Despite the noted potential for team flow to enhance a team's effectiveness, productivity, performance, and capabilities, studies on the construct in the workplace context are scarce. Most research on flow at the group level has been focused on performance in athletics or the arts, and looks at the collective experience. But, the context of work has different parameters, which necessitate a look at individual and team level experiences. In this review, we extend current theories and essay a testable, multilevel model of team flow in the workplace that includes its likely prerequisites, characteristics, and benefits.     

实验诊断临床思维程序的必要性及其内容

为提高临床实验诊断的效率和准确性,提出编写“实验诊断临床思维程序”的观点。从实验诊断学的特性及发展趋势方面论述了该程序的必要性,并初步拟定了包括项目选择、结果判断和结果应用三个部分的实验诊断临床思维程序。     

Prior expectation and the interpretation of natural language quantifiers

Abstract

The interpretation of natural language quantifiers depends, in part, on one's prior expectations about what the proportion being described might be. This hypothesis is tested empirically, by comparing the interpretation of 10 different quantifier expressions in three contexts which contained proportions about which subjects' expectations were reliably different (Experiment 1). It is further argued that quantifiers perform many functions which cannot be observed by considering only the proportion(s) denoted by a quantifier. The experimental evidence presented shows that quantifiers can provide information about what the user of the quantifier had expected before “knowing the facts” (Experiment 2). It is also clear that when writers produce a quantifier, they can reveal their assumptions about the prior expectations held by their readers (Experiment 2).