Treatment Adherence in Children with Sickle Cell Disease: Disease-Related Risk and Psychosocial Resistance Factors

To identify disease-related risk factors and psychosocial resistance factors that impact adherence to prescribed treatment in the context of admission to a Hematology Acute Care Unit (HACU) designed to provide acute care for children with sickle cell disease (SCD) presenting with pain or fever. A total of 73 primary caregivers and 24 children (if age 8 or older) completed standardized forms during the HACU admission. Treatment adherence variables (medical staff rating, SCD-related care activities, percentage of agreement between treatment recommendations made and care activities, and attendance at hematology clinic) indicated moderate-to-high adherence. Based on regression analyses, the risk variable of disease-related stress and the resistance variables of family flexibility and less reliance on passive coping accounted for significant portions of the variance in treatment adherence. Empirical evaluation of interventions designed to improve communication regarding expectations for the care of children with SCD and to support active family problem solving during times of SCD-related stress must be ongoing.     

Treatment, Age, and Time-Related Predictors of Behavioral Outcome in Pediatric Brain Tumor Survivors

The research has shown that children surviving cancer are at risk for long-term emotional and behavioral problems secondary to the cumulative effects of cranial irradiation and chemotherapy. The purpose of this study was to investigate the emotional and behavioral outcome of children diagnosed with brain tumor and treated with cranial irradiation and chemotherapy by looking at the association between treatment, time, age, and cognitive-related variables on externalizing and internalizing behaviors at 3 years posttreatment. Fifty-four brain tumor survivors were administered a neuropsychological test battery, whereas the parents filled out the CBCL and Conners' Parent Rating Scale. The results indicate that chemotherapy treatment with vincristine, cytoxan, cisplantinum, and/or VP16 was related to poorer internalizing and externalizing behavioral outcome, especially attention, social withdrawal, and anxious–depressive symptomatology. Age at time of diagnosis or treatment, time since discontinuation of treatment, type and/or total dose of radiation therapy was not significantly correlated with any of the behavioral outcome scales. Verbal memory and learning deficits accounted for a significant portion of the variance in social withdrawal, whereas lower scores in overall intellectual functioning and verbal fluency was related to disturbances in attention, inhibition, and social functioning. The findings suggest that children treated with 1 or a combination of any of the aforementioned chemotherapy agents who exhibit declines in intellectual functioning and memory are at increased risk for long-term behavioral problems 3 years after treatment cessation. These findings support the importance for early psychotherapeutic and supportive intervention services immediately after treatment cessation, with the goal of circumventing these potentially debilitating emotional problems.     

Psychoeducational Interventions with Pediatric Cancer Patients: Part II. Effects of Information and Skills Training on Health-Related Outcomes

In Part I of this paper, we described a model that was used as a framework for reviewing studies of psychoeducational interventions intended to influence illness- and treatment-related behaviors and attitudes in pediatric cancer patients. In Part II, we distinguish between interventions that attempt to influence patients' behaviors just by providing information and interventions that specifically teach skills related to the behaviors they are trying to change. Many types of psychoeducational interventions appear to be effective and those that are training-based generally appear more effective than those that are information-based. Training-based interventions may face a barrier to wide adoption because they are resource-costly, but the development of digital-based training interventions may potentially overcome this barrier.     

道德哲学建基在错误之上吗？

责任或义务是伦理学中最基本的概念。它是客观的、绝对自明的,因而是不可定义的、无需推理的。人们既不能从别的非伦理的事实或非伦理的属性中推出义务,也不能把它归约为任何其它伦理属性。以往的各种伦理理论的错误在于用一些其它伦理属性来规定责任,从而使其丧失了绝对客观的和自明的意义,其结果是使伦理学长期陷入困境之中。     

不同加工与记忆编码关系的ERP研究

通过事件相关电位(ERPs)记录,探讨了深、浅2种加工与记忆编码的相互关系。研究结果表明,（1）在深、浅两种加工条件下,首次使用汉字材料,获得了ERP相继记忆效应（Dm),随后再认正确的ERPs比随后再认不正确的ERPs有更大的晚正成分。（2）深加工的Dm效应始于N2波的前支（230－280ms)和N2波之后（395－800ms);而浅加工的Dm效应发生在345－490ms之间。深、浅加工的Dm效 涉及不同的脑区,这一结果支持深、浅两种加工的Dm效应可能是分离的结论。     

家庭游戏中的母亲控制策略与儿童顺从行为

以42个3岁儿童及其母亲为被试,考察在家庭自由游戏中母亲的控制策略和儿童的顺从行为之间的关系。结果表明：（1）在亲子交往中,母亲使用直接命令的频次最多,间接命令次之,否定控制最少。（2）3岁儿童对母亲控制的顺从率为56．1％;在儿童的不顺从行为中,无技巧不顺从占优势,其中消极不顺从的频次最多。（3）母亲的弱控制策略与儿童的顺从行为相关最高;强控制策略与儿童的无技巧不顺从相关最高。（4）在儿童不顺从时,母亲的弱控制策略容易导致儿童的顺从行为,强控制策略则容易导致儿童的情境性顺从行为。     

The value of stress-management interventions in life-threatening medical conditions

Emotional stress has been associated with the development and progression of several chronic medical conditions. Recently, researchers have assessed the impact of stress-management interventions on patients' psychological functioning, quality of life, and various disease outcomes, including survival. This review summarizes the value of stress-management techniques in the treatment of two important, life-threatening conditions: coronary heart disease and cancer. Results from randomized clinical trials indicate that psychological interventions can improve patients' psychological functioning and quality of life. However, there is limited evidence to suggest that these interventions significantly reduce morbidity and mortality.     

异体造血干细胞移植问题、发展与思考

异体造血干细胞移植(Allo-HSCT)已成为治疗恶性血液病及其他各种疾病的有效方法之一。在Allo-HSCT中由于供体和受体免疫屏障的存在。从而一开始就是一个供受体矛盾的对立统一的过程。对其中矛盾的研究和解决充满了辩证唯物的哲学思想。也促使Allo-HSCT技术不断发展。新的方法和理念不断出现。使Allo-HSCT治疗白血病的疗效不断提高。     

浅析心电波形唯一性假说

通过对海量心电图资料的分析，发现每个人的心电图波形绝然不同，均有其自身特点，也即具有唯一性，而同一人的心电波形在出生后至18岁成年前如人的容貌、身高、体重一样变化较大，成年后则相对稳定、基本不变，我们认为心电波形如同其他生物特征一样具有生物特征的显著特点，由此提出心电图心电波形具有唯一性的假说。     

把言情绪、共话健康——全国第五届情绪与健康心理学学术研讨会综述

<正>2019年4月26～28日,全国第五届情绪与健康心理学学术研讨会在信阳师范学院隆重召开。本次会议由中国心理学会情绪与健康心理学专业委员会主办,信阳师范学院、河南省心理学会、深圳市心理学会承办。中国心理学会前理事长、中科院心理所所长傅小兰,中国心理学会副理事长、中国心理学会情绪与健康心理学专业委员会主任李红,河南省心理学会理事长、河南师范大学党委书记赵国祥,中国心理学会秘书长、首都师范大学教授罗劲,深圳大学教授罗跃嘉,华东师范大学教授周永