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91.
神经管缺陷(NTDS)是一种常见的先天性中枢神经系统畸形,其发生率占据我国出生缺陷的前列。本文从其发病原因、产前诊断及预防措施进行系统分析,希望能找出一条降低其发生率的有效途径,从而进一步提高我国的人口素质。 相似文献
92.
Burgos JE 《Journal of the experimental analysis of behavior》2007,88(1):115-130
This article presents an interpretation of autoshaping, and positive and negative automaintenance, based on a neural-network model. The model makes no distinction between operant and respondent learning mechanisms, and takes into account knowledge of hippocampal and dopaminergic systems. Four simulations were run, each one using an A-B-A design and four instances of feedfoward architectures. In A, networks received a positive contingency between inputs that simulated a conditioned stimulus (CS) and an input that simulated an unconditioned stimulus (US). Responding was simulated as an output activation that was neither elicited by nor required for the US. B was an omission-training procedure. Response directedness was defined as sensory feedback from responding, simulated as a dependence of other inputs on responding. In Simulation 1, the phenomena were simulated with a fully connected architecture and maximally intense response feedback. The other simulations used a partially connected architecture without competition between CS and response feedback. In Simulation 2, a maximally intense feedback resulted in substantial autoshaping and automaintenance. In Simulation 3, eliminating response feedback interfered substantially with autoshaping and automaintenance. In Simulation 4, intermediate autoshaping and automaintenance resulted from an intermediate response feedback. Implications for the operant-respondent distinction and the behavior-neuroscience relation are discussed. 相似文献
93.
94.
后悔的认知机制和神经基础 总被引:3,自引:0,他引:3
后悔是基于对不利或相对不利行为结果的反事实思维诱发的一种复杂的负性社会情绪,对我们日常生活的决策和身心健康具有重大的影响。与失望情绪相比,后悔在现象学、产生条件以及评价方式等方面具有明显的差异。后悔不仅会受到个体的行为方式、人格特征、归因等因素的影响,而且还会受到结果信息属性的影响。后悔的预期和体验涉及的功能性脑区主要包括:眶额皮层、扣带前回、海马、杏仁核。研究后悔的实验方法和技术手段有待于进一步拓展,后悔的认知机制和神经基础还有待于进一步探讨和完善 相似文献
95.
G. Gangadhar D. Joseph A.V. Srinivasan D. Subramanian R.G. Shivakeshavan N. Shobana V.S. Chakravarthy 《Human movement science》2009,28(5):602
Parkinsonian handwriting is typically characterized by micrographia, jagged line contour, and unusual fluctuations in pen velocity. In this paper we present a computational model of handwriting generation that highlights the role of the basal ganglia, particularly the indirect pathway. Whereas reduced dopamine levels resulted in reduced letter size, transition of STN–GPe dynamics from desynchronized (normal) to synchronized (PD) condition resulted in increased fluctuations in velocity in the model. We also present handwriting data from PD patients (n = 34) who are at various stages of disease and had taken medication various lengths of time before the handwriting sessions. The patient data are compared with those of age-matched controls. PD handwriting statistically exhibited smaller size and larger velocity fluctuation compared to normal handwriting. 相似文献
96.
Events have beginnings, ends, and often overlap in time. A major question is how perceivers come to parse a stream of multimodal information into meaningful units and how different event boundaries may vary event processing. This work investigates the roles of these three types of event boundaries in constructing event temporal relations. Predictions were made based on how people would err according to the beginning state, end state, and overlap heuristic hypotheses. Participants viewed animated events that include all the logical possibilities of event temporal relations, and then made temporal relation judgments. The results showed that people make use of the overlap between events and take into account the ends and beginnings, but they weight ends more than beginnings. Neural network simulations showed a self-organized distinction when learning temporal relations between events with overlap versus those without. 相似文献
97.
98.
视觉意识及其神经机制 总被引:1,自引:0,他引:1
视觉意识的神经机制是当前认知神经科学研究的热点问题之一。过去普遍认为视觉信息加工主要有两条通路:腹侧通路和背侧通路;而新近的研究表明还存在不经过初级视觉皮层(V1区)的第三条通路。高级视觉皮层、V1区和皮层下结构都对意识觉知的产生起到了相应的作用。已有的实验证据表明,意识的产生过程异常复杂,仍有很多问题值得继续深入讨论和研究。 相似文献
99.
Kristjánsson A 《Scandinavian journal of psychology》2007,48(2):97-113
This paper presents a review and summary of experimental findings on the role of attention in the preparation of saccadic eye movements. The focus is on experiments where performance of prosaccades (saccades towards a suddenly appearing item) and antisaccades (saccades of equal amplitude in the direction opposite to where the target moved) is compared. Evidence suggests that these two opposite responses to the same stimulus event entail competition between neural pathways that generate reflexive movements to the target and neural mechanisms involved in inhibiting the reflex and generating a voluntary gaze shift in the opposite direction to the target appearance. Evidence for such a competition account is discussed in light of a large amount of experimental findings and the overall picture clearly indicates that this competition account has great explanatory power when data on saccadic reaction times and error rates are compared for the two types of saccade. The role of attention is also discussed in particular in light of the finding that the withdrawal of attention by a secondary task 200 to 500 ms before the saccade target appears, leads to speeded antisaccades (without a similar increase in error rates), showing that the results do not simply reflect a speed-accuracy trade-off. This result indicates that the tendency for "reflexive" prosaccades is diminished when attention is engaged in a different task. Furthermore, experiments are discussed that show that as the tendency for a reflexive prosaccade is weakened, antisaccades are speeded up, further supporting the competition account of pro- and antisaccade generation. In the light of evidence from neurophysiology of monkeys and humans, a tentative model of pro- and antisaccade generation is proposed. 相似文献
100.
Ellis, Ansorge and Lavidor (2007) [Ellis, A.W., Ansorge, L., & Lavidor, M. (2007). Words, hemispheres, and dissociable subsystems: The effects of exposure duration, case alternation, priming and continuity of form on word recognition in the left and right visual fields. Brain and Language, 103, 292–303.] presented three experiments investigating the effects of exposure duration and format (normal vs mixed or alternating case) on the recognition of words presented in the left and right visual fields. The experiments were conducted within the framework of ‘dissociable neural subsystems theory’ developed by Marsolek and colleagues. Marsolek and Deason (2007) [Marsolek, C.J. & Deason, R.G. (2007). Hemispheric asymmetries in visual word-form processing: Progress, conflict, and evaluating theories. Brain and Language, 103, 304–307.] offer some reflections on our paper, including alternative interpretations of some of our findings. We respond to those reflections in this reply. 相似文献