Exposure to Repetitive Tasks Induces Motor Changes Related to Skill Acquisition and Inflammation in Rats

The authors elucidate exposure-response relationships between repetitive tasks, inflammation, and motor changes with work-related musculoskeletal disorders. Using a rat model of reaching and handle pulling, they examined effects of performing a high-repetition, low-force (HRLF); low-repetition, high-force (LRHF); or high-repetition, high-force (HRHF) task (2 hr/day, 3 days/week, 12 weeks) on reach rate and force, percentage of successful reaches, duration of participation, and grip strength. Reach rate and reach force improved with HRLF, and percentage success increased in all groups in Week 9, and in HRLF and HRHF in Week 12, indicative of skill acquisition. Duration and grip strength showed force-dependent declines with task performance. A subset of HRHF rats received ibuprofen in Weeks 5–12. Ibuprofen significantly improved reach rate, reach force, and duration in treated rats, indicative of an inflammatory influence on reach performance. Ibuprofen improved percentage of successful reaches in Week 9, although this increase was not sustained. However, declines in grip strength, a nocifensive behavior, were not prevented by ibuprofen. Examination of cervical spinal cords of untreated and ibuprofen treated HRHF rats showed increased IL-1beta, an inflammatory cytokine, in neurons. These findings suggest that only a preventive intervention could have addressed all motor declines.     

False Memories in Individuals at Risk for Developing an Eating Disorder

In the present study, the authors used the Roediger and McDermott paradigm (H. L. Roediger & K. B. McDermott, 1995) to examine the creation of false memories in individuals at risk for developing an eating disorder. Thirty-three controls and 34 individuals at risk for eating disorders studied 6 word lists taken from the paradigm. Three lists were food related (bread, fruit, sweet), and 3 were not food related (king, doctor, black). Both groups produced false memories (i.e., recalled or recollected words that were not presented in the lists), and controls actually produced more false memories than the at-risk individuals produced in the recall of the food-related items. Groups did not differ in their recall of items not related to food.     

Occupational Therapy Intervention in the Treatment of Alcoholics

The first section of this article will provide the rationale for all occupational therapists to learn extensively about the isease of alcoholism regardless of area of practice or type of agency where employed. It will offer su estions on how this learning can take place. The second section will take an historic look at occupational therapy literature documenting the use of occupational therapy in alcoholism rehabilitation from 1941 to the present. It will describe modalities currently being used by occupational therapists in alcoholism rehabilitation and discuss expansion of occupational therapy in this practice area.     

Critical Issues in Causation and Treatment of Autism: Why Fads Continue to Flourish

The increasing incidence of autism and the lack of specific answers regarding causation have given rise to unproven educational interventions and medical treatments. Parents of a newly diagnosed child can easily fall prey to interventions that promise cures. These interventions may be harmful and, thus, pose one of the critical issues in special education today. This article will discuss some of the suspect interventions that have been popularized through the media (i.e., celebrities, journalists, and professional organizations). The authors argue that using the scientific method is clearly the antidote for pseudoscience; the need for accurate research-based decision making is apparent.     

Processing of musical structure by high-functioning adolescents with autism spectrum disorders

Enhanced pitch perception and memory have been cited as evidence of a local processing bias in autism spectrum disorders (ASD). This bias is argued to account for enhanced perceptual functioning (Mottron &; Burack, 2001 Mottron, L. and Burack, J. A. 2001. “Enhanced perceptual functioning in the development of autism”. In The development of autism: Perspectives from theory to research, Edited by: Burack, J. A., Charman, T., Yirmiya, N. and Zelazo, P. R. 131–147. Mahwah, NJ: Lawrence Erlbaum.  [Google Scholar]; Mottron, Dawson, Soulières, Hubert, &; Burack, 2006 Mottron, L., Dawson, M., Soulières, I., Hubert, B. and Burack, J. 2006. Enhanced perceptual functioning in autism: An update, and eight principles of autistic perception. Journal of Autism and Developmental Disorders, 36(1): 27–43. doi:10.1007/s10803-005-0040-7[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) and central coherence theories of ASD (Frith, 1989 Frith, U. 1989. Autism: Explaining the enigma, Oxford: United Kingdom: Blackwell.  [Google Scholar]; Happé &; Frith, 2006 Happé, F. and Frith, U. 2006. The weak coherence account: Detail-focused cognitive style in autism spectrum disorders. Journal of Autism and Developmental Disorders, 36(1): 5–25. doi:10.1007/s10803-005-0039-0[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]). A local processing bias confers a different cognitive style to individuals with ASD (Happé, 1999 Happé, F. 1999. Autism: Cognitive deficit or cognitive style?. Trends in Cognitive Sciences, 3(6): 216–222. doi:10.1016/S1364-6613(99)01318-2[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]), which accounts in part for their good visuospatial and visuoconstructive skills. Here, we present analogues in the auditory domain, audiotemporal or audioconstructive processing, which we assess using a novel experimental task: a musical puzzle. This task evaluates the ability of individuals with ASD to process temporal sequences of musical events as well as various elements of musical structure and thus indexes their ability to employ a global processing style. Musical structures created and replicated by children and adolescents with ASD (10–19 years old) and typically developing children and adolescents (7–17 years old) were found to be similar in global coherence. Presenting a musical template for reference increased accuracy equally for both groups, with performance associated to performance IQ and short-term auditory memory. The overall pattern of performance was similar for both groups; some puzzles were easier than others and this was the case for both groups. Task performance was further found to be correlated with the ability to perceive musical emotions, more so for typically developing participants. Findings are discussed in light of the empathizing-systemizing theory of ASD (Baron-Cohen, 2009 Baron-Cohen, S. 2009. Autism: The Empathizing-Systemizing (E-S) Theory. Annals of the New York Academy of Sciences, 1156: 68–80. doi:10.1111/j.1749-6632.2009.04467.x[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) and the importance of describing the strengths of individuals with ASD (Happé, 1999 Happé, F. 1999. Autism: Cognitive deficit or cognitive style?. Trends in Cognitive Sciences, 3(6): 216–222. doi:10.1016/S1364-6613(99)01318-2[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]; Heaton, 2009 Heaton, P. 2009. Assessing musical skills in autistic children who are not savants. Philosophical Transactions of the Royal Society Biological Sciences, 364: 1443–1447. doi:10.1098/rstb.2008.0327[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]).     

Deeper attentional masking by lateral objects in children with autism

Autism spectrum disorder (ASD) is often associated with a detail-oriented perception and overselective attention in visual tasks, such as visual search and crowding. These results were obtained manipulating exclusively the spatial properties of the stimuli: few is known about the spatio-temporal dynamics of visual processing in ASD. In this study we employed an attentional masking (AM) paradigm comparing children with ASD and IQ-matched typically developing (TD) controls. The AM effect refers to an impaired identification of a target followed by a competitive masking object at different proximities in space and time. We found that ASD and TD groups did not differ in the AM effect provoked by the competitive object displayed in the same position of the target. In contrast, children with ASD showed a deeper and prolonged interference than the TD group when the masking object was displayed in the lateral position. These psychophysical results suggest that the inefficient attentional selection in ASD depends on the spatio-temporal interaction between competitive visual objects. These evidence are discussed in the light of the ASD altered neural connectivity hypothesis and the reentrant theory of perception.     

Psychometric evaluation of the eating disorder inventory (edi) in a clinical group

Abstract

This study examined the psychometric properties of the Eating Disorder Inventory (EDI) with a clinical sample of 79 female clients seen at an outpatient eating disorder program. The means and standard deviations for the bulimia nervosa subgroup in this study (n = 48) compared favorably with the bulimia group in the EDI Manual Supplement (1986) on all eight subscales, except Drive for Thinness. The present non-student sample had significantly lower scores on this particular subscale than did the norm group (mostly students). Another difference was that the local bulimic subgroup had significantly higher present and minimum weights (as a percentage of the expected average weight according to height). The EDI subscales also displayed respectable internal consistency reliability with this sample. In contrast to previous research, however, only five factors were found in a factor analysis rather than eight corresponding to the original subscales for the EDI. Differences between bulimic and a not-otherwise-specified (NOS) diagnostic groups were also found on both the EDI Ineffectiveness and Bulimia subscales (NOS had lower scores). The results of this study are discussed in terms of the importance of undertaking local standardization of tests in clinical settings.     

Psychosocial consequences of recurrent vertigo

Abstract

Chronic vertigo is known to be associated with anxiety and depression in a significant proportion of patients, but there have been no systematic investigations into beliefs and behaviour related to recurrent vertigo. Twenty-three individuals with vertigo of various types were interviewed, generating over two thousand statements about vertigo and its psychosocial consequences. By means of progressive categorisation these were condensed into four tables of summary statements representing prevalent reactions to and effects of vertigo. Vertigo is viewed as intrinsically frightening and potentially stigmatising. In an attempt to avoid provoking attacks, particularly in public, subjects tended to impose restrictions on their activities and lifestyle which generated further feelings of helplessness and frustration. The statements obtained in this study provide an empirical basis for the development of a model that may be used to formulate predictions about the relationship between vertigo, handicap and distress, and the benefits of intervention.     

A comparison of working memory profiles in school-aged children with Specific Language Impairment,Attention Deficit/Hyperactivity Disorder,Comorbid SLI and ADHD and their typically developing peers

The association between specific language impairment (SLI), attention deficit/hyperactivity disorder (ADHD), and working memory (WM) was examined. WM has been implicated in language acquisition and models of ADHD; however, evidence for WM deficits in SLI and ADHD has been inconsistent. The components of Baddeley's WM model were investigated in 18 children with SLI, 16 children with ADHD, 11 children with comorbid SLI+ADHD, and 24 typically developing (TD) children. The presence of SLI resulted in deficits in more components of WM than the presence of ADHD indicating that children with SLI are more vulnerable to WM deficits than those with ADHD.