Brain activity patterns of phonemic representations are atypical in beginning readers with family risk for dyslexia

There is an ongoing debate whether phonological deficits in dyslexics should be attributed to (a) less specified representations of speech sounds, like suggested by studies in young children with a familial risk for dyslexia, or (b) to an impaired access to these phonemic representations, as suggested by studies in adults with dyslexia. These conflicting findings are rooted in between study differences in sample characteristics and/or testing techniques. The current study uses the same multivariate functional MRI (fMRI) approach as previously used in adults with dyslexia to investigate phonemic representations in 30 beginning readers with a familial risk and 24 beginning readers without a familial risk of dyslexia, of whom 20 were later retrospectively classified as dyslexic. Based on fMRI response patterns evoked by listening to different utterances of /bA/ and /dA/ sounds, multivoxel analyses indicate that the underlying activation patterns of the two phonemes were distinct in children with a low family risk but not in children with high family risk. However, no group differences were observed between children that were later classified as typical versus dyslexic readers, regardless of their family risk status, indicating that poor phonemic representations constitute a risk for dyslexia but are not sufficient to result in reading problems. We hypothesize that poor phonemic representations are trait (family risk) and not state (dyslexia) dependent, and that representational deficits only lead to reading difficulties when they are present in conjunction with other neuroanatomical or—functional deficits.     

Adjusting for information inflation due to local dependency in moderately large item clusters

When multiple items are clustered around a reading passage, the local independence assumption in item response theory is often violated. The amount of information contained in an item cluster is usually overestimated if violation of local independence is ignored and items are treated as locally independent when in fact they are not. In this article we provide a general method that adjusts for the inflation of information associated with a test containing item clusters. A computational scheme was presented for the evaluation of the factor of adjustment for clusters in the restrictive case of two items per cluster, and the general case of more than two items per cluster. The methodology was motivated by a study of the NAEP Reading Assessment. We present a simulated study along with an analysis of a NAEP data set.The research was supported under the National Assessment of Educational Progress (Grant No. R999G30002) as administered by the Office of Educational Research and Improvement, U.S. Department of Education. This work was started when the author was at the Division of Statistics and Psychometrics at the Educational Testing Service. The author thanks Juliet Shaffer, Bob Mislevy, Eric Bradlow, three reviewers and an associate editor for their helpful comments on the paper.     

An analysis and synthesis of multiple correspondence analysis,optimal scaling,dual scaling,homogeneity analysis and other methods for quantifying categorical multivariate data

We discuss a variety of methods for quantifying categorical multivariate data. These methods have been proposed in many different countries, by many different authors, under many different names. In the first major section of the paper we analyze the many different methods and show that they all lead to the same equations for analyzing the same data. In the second major section of the paper we introduce the notion of a duality diagram, and use this diagram to synthesize the many superficially different methods into a single method.The ideas in this paper were worked out by the first author, with some suggestions provided by the second. The current version of this paper has evolved from three previous versions, the first two written by the first author.     

Conformity of two sociometric relations

The problem of comparing two sociometric relations or measurements (A andB) recorded in distinct sociomatrices was originally discussed by Katz and Powell in the early 1950's and Hubert and Baker in the late 1970's. The problem is considered again using a probabilistic model designed specifically for discrete-valued network measurements. The model allows for the presence of various structural tendencies, such as reciprocity and differential popularity. A parameter that isolates the tendency for actors to choose other actors on both relations simultaneously is introduced, and estimated conditional on the presence of other parameters that reflect additional important network properties. The parameter is presented as a symmetric index but is also generalized to the predictive (A onB orB onA) situation. This approach to the problem is illustrated with the same data used by the earlier solutions, and the unique nature of the two relations in the data set (A = received choices,B = perceived choices), as it affects the modeling, is discussed. Significance tests for the parameter and related parameters are described, as well as an extension to more than two relations.Research support provided by National Science Grant #SES84-08626 to the University of Illinois at Urbana-Champaign. I am grateful to Dawn Iacobucci and Sheila Weaver for assistance with the research reported here, and to Carolyn Anderson, James Green, David Holtgrave, and four anonymous referees for comments on the paper.     

Describing the elephant: Structure and function in multivariate data

There is a unity underlying the diversity of models for the analysis of multivariate data. Essentially, they constitute a family models, most generally nonlinear, for structural/functional relations between variables drawn from a behavior domain.     

Fitting multivariage normal finite mixtures subject to structural equation modeling

This paper is about fitting multivariate normal mixture distributions subject to structural equation modeling. The general model comprises common factor and structural regression models. The introduction of covariance and mean structure models reduces the number of parameters to be estimated in fitting the mixture and enables one to investigate a variety of substantive hypotheses concerning the differences between the components in the mixture. Within the general model, individual parameters can be subjected to equality, nonlinear and simple bounds constraints. Confidence intervals are based on the inverse of the Hessian and on the likelihood profile. Several illustrations are given and results of a simulation study concerning the confidence intervals are reported.     

Multivariate normal integrals and contingency tables with ordered categories

Ak-dimensional multivariate normal distribution is made discrete by partitioning thek-dimensional Euclidean space with rectangular grids. The collection of probability integrals over the partitioned cubes is ak-dimensional contingency table with ordered categories. It is shown that loglinear model with main effects plus two-way interactions provides an accurate approximation for thek-dimensional table. The complete multivariate normal integral table is computed via the iterative proportional fitting algorithm from bivariate normal integral tables. This approach imposes no restriction on the correlation matrix. Comparisons with other numerical integration algorithms are reported. The approximation suggests association models for discretized multivariate normal distributions and contingency tables with ordered categories.The contingency-table approach occurred to me while I was collaborating with Paul Holland of the Educational Testing Service in 1985 on bivariate dependence functions. Holland maintains a belief that the continuous can learn from the discrete. This work is a reassertion of his claim.This research was sponsored by the National Science Council, Republic of China.     

Tool use by chimpanzees (Pan troglodytes) of the Arnhem Zoo community

Abstract: Chimpanzees have a large repertoire of tool-use behaviors. This study reports on the variety and the extent of tool use exhibited by the chimpanzees of the Arnhem Zoo community in The Netherlands, living in an enriched captive setting since 1971. The use of tools by 29 chimpanzees aged from 0 to 37 years was observed. We identified 13 types of tool use comparable to those found in the wild. Some of these types of tool use seem to be specific to this community, and can be explained by the ecological characteristics of this captive setting. Chimpanzees started to use tools from the age of 2 years. Young chimpanzees, from 5 to 9 years old, showed a greater repertoire of tool use than infants and adults. All types of tool use in the community have appeared by the age of 10, the age of puberty for chimpanzees. Multivariate analysis was applied for the 29 individuals by 13 types of tool use in a one-zero matrix. The results show two major categories of tool use, one in a practical or substantial context and the other in a nonpractical or play context. The subjects clustered into groups reflecting developmental stages, although there are great individual differences. In conclusion, this captive community provides a unique opportunity to clarify the details of tool use by chimpanzees.     

Univariate repeated measures techniques applied to multivariate data

Repeated measures designs in psychology have traditionally been analyzed by the univariate mixed model approach, in which the repeated measures effect is tested against an error term based on the subject by treatment interaction. This paper considers the extension of this analysis to designs in which the individual repeated measures are multivariate. Sufficient conditions for a valid multivariate mixed model analysis are given, and a test is described to determine whether or not given data satisfy these conditions.