Genetic Counseling for Fragile X Syndrome: Recommendations of the National Society of Genetic Counselors

The National Society of Genetic Counselors' (NSGC) recommendations for fragile X syndrome (FXS) genetic counseling are intended to assist health care professionals who provide genetic counseling for individuals and families in whom the diagnosis of FXS is strongly suspected or has been made. The recommendations are the opinions of genetic counselors with expertise in FXS counseling and are based on clinical experience, a review of pertinent English language medical articles, and reports of expert committees. These recommendations should not be construed as dictating an exclusive course of management, nor does use of such recommendations guarantee a particular outcome. These recommendations do not displace a health care provider's professional judgment based on the clinical circumstances of a particular client.     

多特征决策策略的信息搜索模式分析

决策策略的使用是不可见的内在过程 ,有效识别出决策者在信息整合时使用的策略对研究策略学习与转换、决策辅助与训练有重要意义。本文介绍了用过程追踪技术获取的信息搜索模式识别多特征决策策略的方法 ,即单步与多步跳转分析 ,并比较了两种方法的应用效果 ,讨论了跳转分析法的优点和局限。     

Fourier‐Motzkin elimination method in MOLP problems

This paper introduces a method for finding the non‐dominated set in criterion space of an MOLP problem based on Fourier–Motzkin Elimination. The method incorporates a procedure that eliminates decision variables from constraints and transforms a feasible region from decision space to criterion space. While avoiding characterization of the efficient set in decision space, it finds the non‐dominated set in criterion space. After the decision maker's most preferred criterion vector has been identified, the corresponding efficient solutions can be found by backward substitution. The method was implemented in MATLAB using a tabular form and computational experiments were conducted. The results indicate that although the method performs well for relatively small problems, it can be computationally intensive for larger problems. Nonetheless, the method is intuitively appealing and it provides useful insights into the geometry and theory of MOLP. As such it makes it a valuable educational tool for students of multi‐criteria decision analysis. Copyright © 2003 John Wiley & Sons, Ltd.     

In the Search for a Post-Communist Syndrome: A Theoretical Framework and Empirical Assessment

A pattern of attitudes and behaviours in the recently freed, post-communist countries is hypothesized as a post-communist syndrome. This study describes the syndrome and its aetiology. The syndrome is viewed as a direct result of long-lasting, oppressive rule and suggests a host of individual and social disorders: learned helplessness, specific manifestations of immorality/incivility, lack of civic culture and civic virtues. Using Q-factor analysis of ‘civic culture’ in a sample of Czech, Hungarian and American students it was found that contrary to the hypothesis, the Czech respondents exhibited a robust civic culture. (© 1997 by John Wiley & Sons, Ltd.)     

论开展亲属活体供肾移植的风险与对策

肾脏移植是救治终末期肾功能衰竭的最佳手段。亲属活体捐献肾脏是扩大供肾来源的有效手段。当前国内开展亲属肾移植存在伦理、法律和健康风险,主要来自供体和医疗两方面。为防范风险,医务人员应严格审查供受者的血缘关系,签署完整规范的法律文书,进行全面细致的术前评估,制定完善的手术方案。     

Establishing the feasibility of direct observation in the assessment of tics in children with chronic tic disorders

Behavior analysis has been at the forefront in establishing effective treatments for children and adults with chronic tic disorders. As is customary in behavior analysis, the efficacy of these treatments has been established using direct-observation assessment methods. Although behavior-analytic treatments have enjoyed acceptance and integration into mainstream health care practices for tic disorders (e.g., psychiatry and neurology), the use of direct observation as a primary assessment tool has been neglected in favor of less objective methods. Hesitation to use direct observation appears to stem largely from concerns about the generalizability of clinic observations to other settings (e.g., home) and a lack of consensus regarding the most appropriate and feasible techniques for conducting and scoring direct observation. The purpose of the current study was to evaluate and establish a reliable, valid, and feasible direct-observation protocol capable of being transported to research and clinical settings. A total of 43 children with tic disorders, collected from two outpatient specialty clinics, were assessed using direct (videotape samples) and indirect (Yale Global Tic Severity Scale; YGTSS) methods. Videotaped observation samples were collected across 3 consecutive weeks and two different settings (clinic and home), were scored using both exact frequency counts and partial-interval coding, and were compared to data from a common indirect measure of tic severity (the YGTSS). In addition, various lengths of videotaped segments were scored to determine the optimal observation length. Results show that (a) clinic-based observations correspond well to home-based observations, (b) brief direct-observation segments scored with time-sampling methods reliably quantified tics, and (c) indirect methods did not consistently correspond with the direct methods.     

A multiple-criteria decision-making approach for the evaluation of retail location

This study proposes an ANP-based evaluation of retail locations. Authors acted as decision analysts and interacted with professionals in Turkish apparel retailing sector for acquiring their knowledge and expertise. As a result, evaluation criteria of the study were identified. These criteria are clustered into five groups: store, other retailers, shopping centre/business district, accessibility, and environmental. The relationship among criteria were assessed and a network was formed. ANP approach was then utilized in order to evaluate possible retail locations for the apparel stores. Besides global preferences of these alternatives, relative importance of the criteria was also revealed. Copyright © 2007 John Wiley & Sons, Ltd.     

“人体器官移植工作体系”框架的初步构想及其伦理使命

借鉴国内外相关成功经验,结合我国实际情况,对“人体器官移植工作体系”的构成以及各系统职能进行初步探讨。研究了该体系在阻止人体器官商业化、提高人体移植器官分配的公平高效性等方面发挥的作用。     

Developing stimulus control of young children's requests to teachers: classwide applications of multiple schedules

Children may recruit their teachers' attention at undesirably high rates or at inconvenient times. Tiger and Hanley (2004) described a multiple-schedule procedure to reduce ill-timed requests, which involved providing children with two distinct continuous signals that were correlated with periods in which teacher attention was either available or unavailable. The current study extended the application of multiple schedules by evaluating the effectiveness of the procedure when implemented by private-school teachers in 3 elementary classrooms. Following the introduction of the multiple schedules, student approaches toward their teacher were maintained during desirable periods but were minimized during undesirable periods.