MORPHINE TOLERANCE AS A FUNCTION OF RATIO SCHEDULE: RESPONSE REQUIREMENT OR UNIT PRICE?

Key pecking by 3 pigeons was maintained by a multiple fixed-ratio 10, fixed-ratio 30, fixed-ratio 90 schedule of food presentation. Components differed with respect to amount of reinforcement, such that the unit price was 10 responses per 1-s access to food. Acute administration of morphine, l-methadone, and cocaine dose-dependently decreased overall response rates in each of the components. When a rate decreasing dose of morphine was administered daily, tolerance, as measured by an increase in the dose that reduced response rates to 50% of control (i.e., the ED50 value), developed in each of the components; however, the degree of tolerance was smallest in the fixed-ratio 90 component (i.e., the ED50 value increased the least). When the l-methadone dose-effect curve was redetermined during the chronic morphine phase, the degree of cross-tolerance conferred to l-methadone was similar across components, suggesting that behavioral variables may not influence the degree of cross-tolerance between opioids. During the chronic phase, the cocaine dose-effect curve shifted to the right for 2 pigeons and to the left for 1 pigeon, which is consistent with predictions based on the lack of pharmacological similarity between morphine and cocaine. When the morphine, l-methadone, and cocaine dose-effect curves were redetermined after chronic morphine administration ended, the morphine and l-methadone ED50s replicated those obtained prior to chronic morphine administration. The morphine data suggest that the fixed-ratio value (i.e., the absolute output) determines the degree of tolerance and not the unit price.     

Maternal and paternal infant representations: A comparison between parents of term and preterm infants

Objective

Research on parental attachment representations after preterm birth is limited and inconclusive. The present study is the first in which maternal and paternal attachment representations after term, moderately and very preterm birth are compared. In addition, special attention was directed toward disrupted attachment representations.

Method

Mothers and fathers of term infants (≥37 weeks of gestational age, n = 71), moderately preterm infants (≥32–37 weeks of gestational age, n = 62) and very preterm infants (<32 weeks of gestational age, n = 56) participated in the present study. Attachment representations (balanced, disengaged, distorted) about their infants were evaluated with the Working Model of the Child Interview (WMCI). To asses disrupted representations the coding of the WMCI was extended with the disrupted scale (WMCI-D).

Results

The three main classifications of attachment representations were not affected by preterm birth. In addition, there were no gender differences in the rate of balanced representations. In case of non-balanced representations however, maternal representations were more often distorted, whereas fathers showed more often disengaged representations. Results further revealed that maternal disrupted attachment representations were marked by role/boundary confusion or disorientation, whereas paternal disrupted attachment representations were characterized by withdrawal.

Conclusion

Given the gender differences it is essential to tailor interventions according to the attachment representations of the parent, in order to be able to alter their non-balanced and/or disrupted attachment representations.     

A categorical approach to infants’ individual differences during the Still-Face paradigm

Cluster analysis was used to create patterns of individual differences reflecting infant behaviors during the initial interaction episode of the Face-to-Face Still-Face (FFSF) paradigm. The clusters were used as the basic unit of analysis for studying infant and maternal behavior and dyadic coordination (i.e., matching and reparation) across FFSF. Seventy-five 4-month-old infants participated with their mothers. Cluster analysis identified three patterns: a Socially Engaged cluster (33%) exhibited high levels of social engagement with their mothers; a Disengaged cluster (60%) showed a tendency to be low in social interaction and a Negatively Engaged cluster (7%) showed high negative emotionality. During the Still-Face episode, the Socially Engaged cluster reacted by reducing focus on their mother and shifting their attention elsewhere, while infants in the Disengaged cluster reduced focus on the environment. Although both the Socially Engaged and Disengaged clusters increased in negative emotionality during the Still-Face, the Socially Engaged group largely recovered during the Reunion, whereas the Disengaged group displayed more negative emotion. The Negatively Engaged cluster demonstrated high levels of negative affect throughout the entire procedure. Mothers of Negatively Engaged infants showed less positive engagement and more social monitoring than mothers in other clusters during all episodes. Dyadic interaction differed between groups, with greater levels of matching and reparations in the engaged group, less in the Disengaged group, and very little coordination in the Negatively Engaged cluster. Findings highlight the role of distinctive patterns of infants’ individual differences in determining early dyadic functioning.     

ICU护士第二受害者经历与支持影响因素分析

采用一般资料调查表、不良事特征调查表、组织支持感量表、心理弹性量表和第二受害者经历与支持量表对大连市11所医院428名ICU护士进行调查。结果显示,ICU护士作为第二受害者经历与支持总分为（82.84±13.58）分;岭回归结果显示,是否经历了护理部层面的分析讨论或汇报、情感性支持、工具性支持、自强型是ICU护士第二受害者经历与支持水平的影响因素（β=−3.177～0.587,P＜0.05）,共同解释23.3%的变化。ICU护士发生不良事件后的心理体验情况不容乐观,医院管理者需重视ICU护士的负性情绪,可通过增加组织支持感和提升心理弹性水平以减轻第二受害者的痛苦体验。

     

ICU患者出院后重返工作岗位相关研究进展

通过查阅国内外文献,从综合ICU患者出院后重返工作岗位相关概念及现状、影响因素（包括人口统计学因素,社会心理学因素,院前、院内、院外相关因素）及干预措施（包括早期康复活动、ICU患者出院后随访、社会支持）四个方面进行综述,同时提出了促进ICU出院后患者重返工作岗位的建议及未来展望,旨在为学者开展ICU出院后患者重返工作岗位相关研究提供参考、为临床工作人员促进ICU患者康复提供护理干预建议,也为社会工作者提供就业指导。

     

Children of divorce in a Scandinavian welfare state: Are they less affected than US children?

A fairly common view holds that children's risks of negative outcomes associated with family dissolution are generally small or even nonexistent in Scandinavia, and clearly smaller than what is usually found in the United States. This view was empirically examined in a recent large-scale study of 4,127 12–15-year-old children in Norway, of whom 623 had experienced parental divorce and lived in a single-mother family. The somewhat paradoxical pattern of findings was as follows: (a) The negative associations between parental divorce and various outcomes were found to be generally very similar in Norway and the United States in spite of the great differences in family policy and welfare benefits for single mothers (at the macro level); and (b) Mediational effects of family economic resources were in both countries most marked for the academic achievement area, and the predictive power of such variables was quite similar, again in spite of the great differences in absolute level of the economic resources available to single-mother families in the two countries. The results cast some doubt on the value of the absolute economic deprivation perspective in explaining the results, and the many Norwegian welfare benefits do not seem to mitigate the association between divorce and negative outcomes for the children involved. Also policy implications derived from the economic deprivation perspective are questioned. Alternative interpretations of the findings involving relative deprivation and economic resources as a partial proxy for other non-economic factors are briefly discussed.     

新生儿重症监护病房患儿家属心理状况分析

探讨新生儿重症监护病房（NICU）住院患儿家属的心理状况及影响因素。采用焦虑自评量表（SAS）及自行设计的调查问卷对190名NICU住院患儿家属进行调查。结果显示患儿家属表现出不同程度的焦虑,与全国常模（29．78±0．46）相比,其焦虑情绪标准分49．54±1．07,高于常模组（P〈O．05）。影响因素主要包括文化水平、家庭人均收入及患儿病情严重程度等。患儿父母关注的主要问题包括：病情严重程度、预后、医护人员解释病情满意度及病房探视制度。笔者认为医护人员应加强与患儿家属的有效沟通,满足其心理需求,提高医疗护理质量,促进医患关系和谐。     

Order of Attainment of the Mental Structures for Five of Piaget's Logical,Infralogical, and Formal Tasks

This study explored the relationship between illegitimate birth and cognitive development among 513 boys on probation. Prior research has shown that being part of a single-parent household leads to diminished verbal capacities and often puts a child in greater danger of abuse and neglect. Frequent abuse is thought to lead to the enhancement of visual and spatial skills relative to verbal skills through a process of “frozen watchfulness”. I hypothesized that illegitimate boys from one-parent homes would have greater verbal-performance discrepancy scores than would boys from other combinations of birth status and family structure. These boys had the lowest verbal IQ and highest performance IQ scores and, hence, the largest discrepancy. These boys also suffered the highest degree of abuse and neglect of all four birth status/family structure combinations studied.