全文获取类型
收费全文 | 281篇 |
免费 | 28篇 |
国内免费 | 7篇 |
专业分类
316篇 |
出版年
2024年 | 1篇 |
2023年 | 3篇 |
2022年 | 2篇 |
2021年 | 6篇 |
2020年 | 5篇 |
2019年 | 9篇 |
2018年 | 11篇 |
2017年 | 10篇 |
2016年 | 6篇 |
2015年 | 7篇 |
2014年 | 11篇 |
2013年 | 46篇 |
2012年 | 9篇 |
2011年 | 2篇 |
2010年 | 3篇 |
2009年 | 12篇 |
2008年 | 14篇 |
2007年 | 23篇 |
2006年 | 19篇 |
2005年 | 14篇 |
2004年 | 10篇 |
2003年 | 6篇 |
2002年 | 6篇 |
2001年 | 18篇 |
2000年 | 9篇 |
1999年 | 7篇 |
1998年 | 3篇 |
1997年 | 8篇 |
1995年 | 3篇 |
1994年 | 2篇 |
1993年 | 6篇 |
1992年 | 8篇 |
1991年 | 1篇 |
1989年 | 4篇 |
1988年 | 2篇 |
1987年 | 2篇 |
1986年 | 1篇 |
1984年 | 2篇 |
1982年 | 1篇 |
1981年 | 1篇 |
1979年 | 1篇 |
1976年 | 2篇 |
排序方式: 共有316条查询结果,搜索用时 0 毫秒
121.
122.
行为遗传学:从宏观到微观的生命研究 总被引:6,自引:2,他引:6
行为遗传学是在多门学科发展的基础上形成的一门交叉学科。从19世纪末期到现在,行为遗传学已跨入第三个世纪。从孟德尔单基因遗传定律到多基因系统与环境交互作用影响复杂的人类行为,从传统的计量遗传学研究到连锁、关联研究再到功能基因组学技术的应用,无论在思想体系还是研究方法上,行为遗传学都取得了突破性进展。尽管行为遗传学在阐明基因究竟怎样影响行为的道路上仍处于起步阶段,但毋庸置疑,这一学科的进步将有助于人类了解自身行为,减轻人类病痛,并最终推动整个社会健康发展。 相似文献
123.
124.
Dehryl A. Mason Paul J. Frick 《Journal of psychopathology and behavioral assessment》1994,16(4):301-323
In this paper, we describe a quantitative summary of 12 twin (n=3795 twin pairs and 3 adoption studies=338 adoptees) published since 1975 which provided 21 estimates of the heritability of antisocial behavior. Medium to large effect sizes were found for genetic influences across studies, with approximately 50% of the variance in measures of antisocial behavior attributable to genetic effects. Although effect sizes did not vary across different definitions of antisocial behavior (criminality, aggression, or antisocial personality), significantly larger estimates of genetic effect were found for severe manifestations of antisocial behavior. The importance of severity was further underscored by the significantly larger effects obtained in studies using clinic-referred samples compared to the effects obtained in studies using volunteer samples. Demographic characteristics of the samples did not influence effect sizes, although studies using more stringent methodology tended to find larger effects. These results must be interpreted in light of the small literature that was suitable for the meta-analysis due to numerous methodological limitations in existing studies. 相似文献
125.
Fifty-six of 80 (70%) full members of the National Society of Genetic Counselors with interest in cancer genetics responded to a 1994 survey regarding their cancer risk counseling practices. This study was undertaken to describe cancer risk counselors and the services they provide and to identify possible differences from general genetic counseling that warrant further study. Of 56 respondents, 41 (75%) were providing CRC. The components of CRC programs are described. Our results found significant differences between CRC and general genetic counseling in terms of training and experience of genetic counselors providing CRC and length and number of counseling sessions per consultand. 51% of respondents had 1–2 years of working in CRC, compared to 17% with 1–2 years experience in genetic counseling (p<0.05). Over one-third had 10 or more years genetic counseling experience. Counselors were more likely to see individuals at risk for cancer for longer counseling sessions (p<0.05) and for additional sessions (p<0.05). 相似文献
126.
The field of clinical genetics has undergone substantial commercialization, including the development of genetics diagnostics companies. Numerous for-profit corporations now offer genetic diagnostic services; until recently, these clinical services were provided almost exclusively through academic, not-for-profit medical centers. Some of these for-profit corporations have business and/or research relationships with academia. An evaluation of the interconnections between academia and the clinical genetics industry is an important first step in analyzing the risks and benefits of commercialization. We analyzed the personnel and business affiliations of 19 major U.S. for-profit clinical genetics diagnostics companies with universities, academic medical centers, and the scientific and medical genetics communities in a 2-year period, 1991–1992. We noted extensive connections between the for-profit sector and academia. At least 17% of high-ranking personnel and 85% of consultants for the companies had one or more academic ties. At least 68% of the companies had one or more business agreements with at least one university or academic medical center. These results raise many issues regarding the delivery of genetic medicine and the structure and function of academic medical genetics centers. 相似文献
127.
This paper explores usage of the concept ofabnormality in medical genetics and proposesdirectives for more careful usage of this concept.The conceptual difficulties are first explored, thena model is developed to assess actual usage, followedby analysis of a sample of genetic textbooks andgenetics literature. It appears that fact andvaluation are often intermingled, that referencestandards used to define 'genetic abnormalities' areoften not clear and that the concept of abnormality isoften used independent of the degree of certainty withwhich the altered genetype develops into a (seriously)harmful phenotype. On the basis of these findings itis argued that more restraint and more careful use ofthe concept of genetic abnormality of medical geneticsis appropriate as well as more agreement on the use ofreference standards. 相似文献
128.
神经心理学的检测手段包括神经心理学测验和仪器检查。行为遗传学是一门在多学科基础上发展形成的的交叉学科。近年来,应用神经心理学手段进行行为遗传学研究,已经取得了一些可喜的进展。 相似文献
129.
研究解偶联蛋白-2基因启动子常见-866G/A基因多态性(UCP2—866G/A)与2型糖尿病发病相关性。用多聚酶链反应-限制内切酶长度多态性技术检测了76例非糖尿病对照(NDM)和115例糖尿病患者(DM)的UCP2—866G/A基因型分布,并分析各基因型与胰岛功能、代谢参数的差异性。结果DM的AA基因型分布显著高于NDM(32.2%vs15.8%,χ^2=6.526,P〈0.038)。在NDM组GG型携带者空腹C肽(FCP)水平高于AA和GG组(两两比较分别为t=2.99,P=0.005和t=2.229,P=0.03);在DM各基因型之间FCP和餐后2小时C肽(2hCP)情况与NDM对照相似,各基因型混和餐刺激后2hCP差异更加明显。结论为UCP2—866G/A基因多态性与大连地区2型糖尿病发病相关,该基因多态性主要影响胰岛β细胞分泌功能。 相似文献
130.
Crisp R 《Science and engineering ethics》1995,1(2):101-110
This paper was presented as part of the 1993 Waynflete Lecture Series onGenes: Science, Law and Ethics, Magdalen College, Oxford University. 相似文献