BDNF基因与抑郁

抑郁的发生发展具有重要的遗传基础。随着细胞分子生物学实验方法以及分子遗传技术的进步, 与神经可塑性有关的BDNF基因作为抑郁遗传学研究的候选基因日益受到关注。概观而言, 已有相关研究主要探查了BDNF基因与抑郁的直接关联, BDNF基因与其他基因对抑郁的交互作用, 以及环境因素对BDNF基因与抑郁关系的调节作用。然而, 研究结论尚存在分歧甚至相互矛盾。其原因包括研究设计、环境测量指标、抑郁测量方法与研究对象种族背景等方面的差异。未来研究可通过采用多基因–环境设计, 考察被试种族、性别和年龄的调节作用, 以及探究潜在的作用机制等进一步推进和深化有关BDNF基因与抑郁关系的研究。     

Personality and sexuality in older adults

Objective: This study explored cross-time associations between personality and multiple components of sexual functioning and behaviour in a large cohort of older adults (n = 5745).

Design: Participants (M_age = 65.57 ± 8.28 years) completed questionnaires in 2010 and 2012.

Main outcome measures: Outcomes explored included sexual attitudes, sexual activity, sexual satisfaction, lifetime sexual partners, sexual orientation and sexual dysfunction.

Results: We found that higher levels of openness and lower levels of agreeableness were related to more liberal attitudes toward sex, a greater number of sexual partners, a higher sex drive, more frequent sexual activity, lower levels of sexual dysfunction and (for women) a greater tendency towards homosexuality. Higher levels of conscientiousness were also related to more conservative attitudes towards sex, lower levels of sexual dysfunction and a greater tendency towards heterosexuality. For sexually active older adults, higher levels of extraversion and lower levels of neuroticism were related to greater sexual satisfaction. Higher levels of extraversion and lower levels of conscientiousness were also related to a greater number of sexual partners in men but not women.

Conclusion: These findings provide evidence that personality is an important correlate of sexual functioning and behaviour in older adults.     

The Cohen–Hoberman inventory of physical symptoms: Factor structure,and preliminary tests of reliability and validity in the general population

Objective: The present study aimed to investigate the factor structure and psychometric properties of the Cohen–Hoberman inventory of physical symptoms (CHIPS). Construct and discriminant validity were examined by assessing associations between factors and subjective health complaints (SHC) inventory subscales in addition to measures of pain sensitivity, perceived stress and psychological distress.

Design: A cross-sectional online survey was conducted with 535 healthy individuals from the general population (80.6% female, mean age = 29.80).

Main outcome measures: Participants completed CHIPS, SHC, perceived stress scale, pain sensitivity questionnaire, and hospital anxiety and depression scale.

Results: Principal components analysis demonstrated that CHIPS comprised 8 ‘symptoms’ factors as follows; ‘sympathetic/cardiac’ (7 items; α = .827), ‘muscular’ (6 items; α = .752), ‘metabolic’ (5 items; α = .736), ‘gastrointestinal’ (5 items; α = .714), ‘vasovagal’ (4 items; α = .743), ‘cold/flu’ (2 items; α = .837), ‘headache’ (2 items; α = .690) and ‘minor haemorrhagic’ (2 items; α = .309). Significant correlations were observed between factors and SHC subscales (moderate-high), pain sensitivity (negligible-low) and levels of perceived stress and anxiety (low-moderate) indicating good construct, and discriminant validity, respectively.

Conclusions: CHIPS is a multidimensional and internally consistent measurement of physical symptoms. The postulated factor structure may be used for research purposes particularly in health psychology, to consistently differentiate between clusters of self-reported symptoms.     

焦虑障碍的认知偏向矫正：应用与争议

认知偏向是焦虑障碍患者的重要认知特征, 是指患者或高焦虑个体对负性或威胁性信息存在认知加工方面的偏向。目前该领域的研究聚焦于注意偏向和解释偏向。近年来, 研究者致力于将认知偏向的矫正应用于焦虑障碍患者的临床治疗, 得到了不一致的结果。本文总结了将认知偏向矫正应用于临床实践的不同方式, 并从主观报告的疗效证据、行为及生理指标的疗效证据, 以及未发现疗效证据的研究三方面回顾了近年来的研究成果。对于结果的高度不一致, 本文从期望效应、干预对象、因变量和其它参数等方面探讨了可能的原因, 并讨论了未来可能的研究方向。     

Exploring the factor structure of the Francis Psychological Type Scales among a sample of Anglican clergy in England

ABSTRACT

The Francis Psychological Type Scales (FPTS) were designed to provide a fresh conceptualisation and operationalisation of psychological type theory suitable for application within self-report quantitative studies in the individual differences tradition. The present study tests the factor structure of this instrument among a sample of 722 Anglican clergy. The Varimax Rotated Solution with Kaiser Normalisation recovered the hypothesised location of 74 of the 80 items across four factors with factor weightings of or above .38. The FPTS are commended for use.     

Construct validation of the Zimbardo Time Perspectives Inventory

The aim of the present study was to validate the factorial structure and psychometric properties of the Zimbardo Time Perspectives Inventory (ZTPI) in a South African student sample. A total of 200 students completed the ZTPI. The sample comprised 58 0.8% female students. Of these, 61.1% were black students and 38.9% were white students. The average age for the sample was 21.59 years. Exploratory and confirmatory factor analyses were used to examine the construct and discriminant validity of the ZTPI. The data suggest ZTPI to comprise four factors of Present-Fatalistic (PF), Present-Hedonistic (PH), Past-Negative (PN), and Past-Positive (PP). Many of the factors cross-loaded onto one or two others, suggesting poor differentiation in the study sample. Scores from the ZTPI were of acceptable reliability. The study results suggest the ZTPI is usable for research purposes in South Africa.     

Are we certain about which measure of intolerance of uncertainty to use yet?

Intolerance of Uncertainty (IU) has been understood as a dispositional tendency to view the presence of negative events as unacceptable and threatening, regardless of the likelihood of those events occurring. The preference over the 12-item vs. 27-item of the IUS has been central to debate. The goals of the present study were to evaluate two competing models of measuring IU with model-fitting analyses and explore model invariance of gender (e.g. men vs. women). A sample of 980 individuals completed an online IUS survey. Results indicated that the two-factor short-form model provided better fit to the data compared to the full-length two-factor model proposed by. Results also indicated that the short-form IUS is gender invariant, suggesting acceptable use among men and women. These findings provide further support of a two-factor structure and suggest that the IUS is appropriate for men and women.     

双语者语言切换代价的影响因素

抑制控制、语言熟练度、任务相关因素和工作记忆容量是双语者语言切换代价的重要影响因素。其中,抑制控制抑或语言熟练程度何者主要调节着双语者的语言切换代价成为抑制控制模型和语言特异性选择模型争论的焦点。为此,未来研究需要在二语习得年龄与语言使用情景等因素是否影响双语者的控制机制、语言切换代价与任务转换代价的本质是否相同、语言切换代价和工作记忆之间的关系及其认知可塑性等领域予以进一步探索。     

The General Factor of Personality and Character: A Reanalysis

Using data from the Texas Twin Project, it was recently reported that 7 measures of character covaried to the extent that they formed a general factor of character (Tucker-Drob, Briley, Engelhardt, Mann, &; Harden, 2016 Tucker-Drob, E. M., Briley, D. A., Engelhardt, L. E., Mann, F. D., &; Harden, K. P. (2016). Genetically-mediated associations between measures of childhood character and academic achievement. Journal of Personality and Social Psychology, 111, 790–815. doi:10.1037/pspp0000098.[Crossref] , [Google Scholar]). In turn the relationship between the general factor of character and the Big Five personality traits were examined. It was found that personality was associated with the general factor of character primarily through the traits of conscientiousness and openness. For several reasons we propose that a more accurate interpretation of the data is that a Big Five personality traits form a general factor of personality, and that the relationship between the general character factor and personality is primarily through the general factor of personality. The results lend some support to this contention and are discussed in relation to the growing interest in covariation among multiple personality traits.     

Equivalent Dynamic Models

Equivalences of two classes of dynamic models for weakly stationary multivariate time series are discussed: dynamic factor models and autoregressive models. It is shown that exploratory dynamic factor models can be rotated, yielding an infinite set of equivalent solutions for any observed series. It also is shown that dynamic factor models with lagged factor loadings are not equivalent to the currently popular state-space models, and that restriction of attention to the latter type of models may yield invalid results. The known equivalent vector autoregressive model types, standard and structural, are given a new interpretation in which they are conceived of as the extremes of an innovating type of hybrid vector autoregressive models. It is shown that consideration of hybrid models solves many problems, in particular with Granger causality testing.