Do eating disorder voice characteristics predict treatment outcomes in anorexia nervosa? A pilot study

Individuals with anorexia nervosa often describe experiencing an internal “voice” of their disorder, which previous research has associated with multiple dimensions of eating pathology. This pilot study examined whether eating disorder measures use invoice characteristics at the outset of outpatient therapy predicted changes in disordered eating over the course of treatment. Participants were 14 individuals meeting ICD-10 criteria for anorexia nervosa. Participants completed measures relating to the severity of disordered eating and voice-related characteristics (perceived voice power and metacognitive appraisals about its nature) at the start and end of therapy. Results indicated that the perceived power of the eating disorder was reduced over the course of outpatient therapy, although its other characteristics remained stable. Greater levels of voice power, omnipotence and benevolence at the outset of therapy were related to greater improvements in eating attitudes. No voice-related characteristics were associated with changes in weight. These findings suggest that voice-related appraisals do not obstruct the effectiveness of outpatient therapies for anorexia nervosa. Further studies are needed to ratify these preliminary findings.     

认知和情绪冲突的监控与解决：来自轻度认知损伤的证据

轻度认知损伤(mild cognitive impairment, MCI)是介于正常老化和痴呆之间的过渡阶段。近年来, 执行控制的损伤被认为是MCI的核心特征之一。当前, 在MCI执行控制的领域内, 对冲突监控与解决的特征及其神经机制的研究较少。本研究拟通过认知及情绪冲突实验范式, 结合脑成像技术, 探讨遗忘型MCI (amnestic MCI, aMCI)认知和情绪冲突的监控与解决的特征及相应的脑激活模式; 通过对比aMCI和正常老年人在认知和情绪冲突任务中激活的神经环路, 考察aMCI是否在执行加工的神经网络上存在激活异常。在上述研究基础上, 研究者拟探讨aMCI在执行控制的冲突监控与解决上是否存在一般性的损伤机制, 同时试图寻找aMCI在执行控制的冲突监控与解决方面的认知及神经生物学标记。这对深入理解痴呆的发病进程并有针对性的开展痴呆的早期识别与干预具有重要的理论意义和实践意义。     

Effects of Friendship Circles on the Social Interactions of Elementary Age Students with Mild Disabilities

This study assessed the effects of Friendship Circles on the social interactions between students with mild disabilities and their nondisabled peers. A multiple probe design was used to analyze the social interactions during lunch. Data also were collected in the form of sociograms and anecdotal records. In addition, generalization was assessed during recess observations. Results indicated that the Friendship Circle intervention produced increases in appropriate interactions at lunch for all three students and for two there were increases in friendly play at recess. Anecdotal data suggested improved social interactions for two of the students throughout the day and improved social behaviors in the general education classroom such as cooperation during group activities. Implications for future research are discussed.     

轻度智力落后学生心理健康问题的研究

本研究使用心理健康诊断测验(MHT)手册对10-16岁(四至九年级)的轻度智力落后学生与智力正常学生间的心理健康水平进行比较研究,结果发现：轻度智力落后学生有不同程度的心理健康问题,随班就读轻度智力落后学生的心理健康问题尤为突出．有待相应有效的教育支持。     

轻度认知损伤重复效应脑电研究：范式及应用

“语义一致性加重复”范式（congruity-plus-repetition paradigm）在早前重复范式的基础上增加了早期语义情境用以控制重复效应的前期成份N400和后期成份P600之间的相互干扰。作者回顾了这种范式在轻度认知损伤（mild cognitive impairment,MCI）的事件相关电位研究领域的应用,并分析了该范式在MCI的识别及预测其向痴呆转归方面的优越性。提示效应的组合更能标记正常认知老化向痴呆的动态过渡;能产生两个或多个效应组合的实验范式将是该领域未来研究方向之一。     

TEACHING SEVERELY MULTIHANDICAPPED STUDENTS TO PUT ON THEIR OWN HEARING AIDS

Two experiments were conducted with six severely multihandicapped students with hearing impairments to: (a) train the six students to put on their own hearing aids independently, and (b) provide an empirical evaluation of a comprehensive instructional program for putting on a hearing aid by assessing acquisition, maintenance, and generalization of that skill across environments. All six students acquired the skill rapidly, with two students requiring remedial training on one step of the program. Because for two of the original three students the newly learned skill failed initially to generalize to other environments, a second experiment was initiated to assess generalization across environments as well as to replicate the efficiency of the acquisition program. When a variation of the multiple-probe baseline technique was used, the behavior of three additional students generalized to other settings without direct training in those settings.     

Are the inhibitory and faciliatory effects during retrieval of semantically related items present in amnestic mild cognitive impairment?

Prefrontal functions subserve inhibition control for retrieval of semantically related items inducing forgetting 19 a-MCI patients and 29 controls underwent neuropsychological evaluation and retrieval-practice paradigm (RPP) to estimate baseline remember (BR), retrieval-induced facilitation (FAC) and retrieval-induced forgetting (RIF). A-MCI patients underwent also 3 T-MRI to assess relationship between regional grey matter (rGM) volumes and RPP indexes Behaviourally, RIF and FAC were both observed controls, while RIF only was observed in a-MCI patients. In patients but not in controls, RIF was associated with cognitive efficiency and FAC with memory performance. Patients showed also associations between BR and rGM volumes in the precuneus, no association was found between rGM volumes and RIF and FAC. A-MCI patients did not benefit from repeated practice during retrieval of studied items, which is likely due to their memory disorder. In contrast, patient cognitive efficiency would drive retrieval suppression of interfering stimuli.     

Use of a self-regulated strategy intervention to improve word problem-solving skills of students with mild disabilities

We investigated the effects of self-regulated strategy instruction on the ability of four elementary-school students with mild handicaps (2 with learning disabilities [LD] and 2 with mild mental retardation [MMR]) to perform 4 types of addition and subtraction word problems. We used a multiple baseline design and a self-instructional strategy to address story problem solving. Results indicated that the strategy was effective in increasing the number of correctly solved word problems. Gains were maintained across a 6 and 8 week follow-up check. The study supports previous research indicating that cognitive strategies are effective for students with LD and suggests that cognitive strategies are appropriate for students with MMR.     

Reliability of the Chronic Mild Stress paradigm: Implications for research and animal welfare

The Chronic Mild Stress (CMS) model for depression has become central to the empirical literature on depression. There are however inconsistencies in the literature concerning the robustness of the phenomenon of anhedonia following CMS procedures. We report that not only did our procedures (modeled on the original reports) fail to induce an anhedonia, but in fact led to increased sucrose consumption. Furthermore, corticosterone levels following CMS procedures were lower than following control procedures. Given that this is not the first report of such findings, it is important to evaluate whether and which aspects of the experimental methodology are necessary or sufficient to induce the state of anhedonia.     

听觉丧失对听障学生时间知觉的影响

本研究采用同时判断任务和时距二分任务,探讨了听觉丧失对听障学生视觉通道的时间知觉的影响及其机制。两个系列实验结果表明,听觉丧失损伤了听障学生视觉通道的时序知觉准确性、敏感性以及时距知觉的敏感性,支持了普遍缺陷假设;但是,听障学生视觉通道的时距知觉的准确性却未受到听觉丧失的显著影响,支持了知觉补偿假设。因此,听觉丧失对听障学生视觉通道的时间知觉的影响可能是基于选择性的机制,这主要取决于不同的时间任务以及知觉属性等因素。